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Murcko scaffold

Ring system with 3 rings and 21 atoms

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
48
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(Cn2cccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(Cn2cccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(2-fluorophenyl)benzamide chemical structure, C17H13ClFN3O, CAS 489451-21-0
4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(2-fluorophenyl)benzamide
CAS 489451-21-0C17H13ClFN3O
N-(3-Chlorophenyl)-4-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide chemical structure, C17H13Cl2N3O, CAS 489451-25-4
N-(3-Chlorophenyl)-4-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide
CAS 489451-25-4C17H13Cl2N3O
Benzamide, 4-[(4-chloro-1H-pyrazol-1-yl)methyl]-N-(2-methoxyphenyl)- chemical structure, C18H16ClN3O2, CAS 514800-71-6
Benzamide, 4-[(4-chloro-1H-pyrazol-1-yl)methyl]-N-(2-methoxyphenyl)-
CAS 514800-71-6C18H16ClN3O2
Dimethyl 5-({4-[(4-chloro-1H-pyrazol-1-yl)methyl]benzoyl}amino)isophthalate chemical structure, C21H18ClN3O5, CAS 957311-05-6
Dimethyl 5-({4-[(4-chloro-1H-pyrazol-1-yl)methyl]benzoyl}amino)isophthalate
CAS 957311-05-6C21H18ClN3O5
N-(4-Acetamidophenyl)-4-[(4-chloropyrazol-1-yl)methyl]benzamide chemical structure, C19H17ClN4O2, CAS 514801-04-8
N-(4-Acetamidophenyl)-4-[(4-chloropyrazol-1-yl)methyl]benzamide
CAS 514801-04-8C19H17ClN4O2
Propan-2-yl 4-[[4-[(4-chloro-3,5-dimethylpyrazol-1-yl)methyl]benzoyl]amino]benzoate chemical structure, C23H24ClN3O3, CAS 489450-75-1
Propan-2-yl 4-[[4-[(4-chloro-3,5-dimethylpyrazol-1-yl)methyl]benzoyl]amino]benzoate
CAS 489450-75-1C23H24ClN3O3
Benzamide, 4-[(4-bromo-1H-pyrazol-1-yl)methyl]-N-(2-fluorophenyl)- chemical structure, C17H13BrFN3O, CAS 514801-22-0
Benzamide, 4-[(4-bromo-1H-pyrazol-1-yl)methyl]-N-(2-fluorophenyl)-
CAS 514801-22-0C17H13BrFN3O
4-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-(3,5-dichlorophenyl)benzamide chemical structure, C17H12BrCl2N3O, CAS 489451-26-5
4-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-(3,5-dichlorophenyl)benzamide
CAS 489451-26-5C17H12BrCl2N3O
N-(4-Methoxy-2-methylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C19H18N4O4, CAS 515177-63-6
N-(4-Methoxy-2-methylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 515177-63-6C19H18N4O4
N-(3-Chloro-2-methylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C18H15ClN4O3, CAS 515175-42-5
N-(3-Chloro-2-methylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 515175-42-5C18H15ClN4O3
4-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(3-bromophenyl)benzamide chemical structure, C17H12Br2N4O3, CAS 491831-00-6
4-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(3-bromophenyl)benzamide
CAS 491831-00-6C17H12Br2N4O3
N-(2-Methylsulfanylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C18H16N4O3S, CAS 515150-23-9
N-(2-Methylsulfanylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 515150-23-9C18H16N4O3S
N-(3,4-Dichlorophenyl)-4-[(3,5-dimethyl-4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C19H16Cl2N4O3, CAS 957482-28-9
N-(3,4-Dichlorophenyl)-4-[(3,5-dimethyl-4-nitropyrazol-1-yl)methyl]benzamide
CAS 957482-28-9C19H16Cl2N4O3
4-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-[3-(trifluoromethyl)phenyl]benzamide chemical structure, C18H12BrF3N4O3, CAS 957399-75-6
4-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-[3-(trifluoromethyl)phenyl]benzamide
CAS 957399-75-6C18H12BrF3N4O3
4-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-(2-methoxyphenyl)benzamide chemical structure, C18H16BrN3O2, CAS 489450-08-0
4-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-(2-methoxyphenyl)benzamide
CAS 489450-08-0C18H16BrN3O2
4-[(4-Bromopyrazol-1-yl)methyl]-N-(3,4-dichlorophenyl)benzamide chemical structure, C17H12BrCl2N3O, CAS 489450-25-1
4-[(4-Bromopyrazol-1-yl)methyl]-N-(3,4-dichlorophenyl)benzamide
CAS 489450-25-1C17H12BrCl2N3O
N-(2-Acetyl-4,5-dimethoxyphenyl)-4-({4-nitro-1H-pyrazol-1-yl}methyl)benzamide chemical structure, C21H20N4O6, CAS 491829-37-9
N-(2-Acetyl-4,5-dimethoxyphenyl)-4-({4-nitro-1H-pyrazol-1-yl}methyl)benzamide
CAS 491829-37-9C21H20N4O6
N-(2,4-Dimethylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C19H18N4O3, CAS 514854-97-8
N-(2,4-Dimethylphenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 514854-97-8C19H18N4O3
N-(2,5-Dichlorophenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C17H12Cl2N4O3, CAS 515176-42-8
N-(2,5-Dichlorophenyl)-4-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 515176-42-8C17H12Cl2N4O3
4-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-(3,4-dimethoxyphenyl)benzamide chemical structure, C19H18BrN3O3, CAS 514799-47-4
4-[(4-Bromo-1H-pyrazol-1-yl)methyl]-N-(3,4-dimethoxyphenyl)benzamide
CAS 514799-47-4C19H18BrN3O3
4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(3,4-dichlorophenyl)benzamide chemical structure, C17H12Cl3N3O, CAS 489450-21-7
4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(3,4-dichlorophenyl)benzamide
CAS 489450-21-7C17H12Cl3N3O
4-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N-(2-fluorophenyl)benzamide chemical structure, C19H17ClFN3O, CAS 489450-15-9
4-[(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-N-(2-fluorophenyl)benzamide
CAS 489450-15-9C19H17ClFN3O
4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(3,4-dimethoxyphenyl)benzamide chemical structure, C19H18ClN3O3, CAS 489450-14-8
4-[(4-Chloro-1H-pyrazol-1-yl)methyl]-N-(3,4-dimethoxyphenyl)benzamide
CAS 489450-14-8C19H18ClN3O3
Isopropyl 4-({4-[(4-chloro-1H-pyrazol-1-yl)methyl]benzoyl}amino)benzoate chemical structure, C21H20ClN3O3, CAS 514817-08-4
Isopropyl 4-({4-[(4-chloro-1H-pyrazol-1-yl)methyl]benzoyl}amino)benzoate
CAS 514817-08-4C21H20ClN3O3