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Murcko scaffold

Ring system with 3 rings and 23 atoms

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
34
With full pages
13
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(S(=O)(=O)N2CCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(S(=O)(=O)N2CCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

N-(4-Fluorophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C17H17FN2O3S, CAS 315240-62-1
N-(4-Fluorophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 315240-62-1C17H17FN2O3S
N-(2-Fluorophenyl)-4-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C17H17FN2O3S, CAS 392251-76-2
N-(2-Fluorophenyl)-4-(pyrrolidine-1-sulfonyl)benzamide
CAS 392251-76-2C17H17FN2O3S
4-(Pyrrolidin-1-ylsulfonyl)-N-(m-tolyl)benzamide chemical structure, C18H20N2O3S, CAS 313254-16-9
4-(Pyrrolidin-1-ylsulfonyl)-N-(m-tolyl)benzamide
CAS 313254-16-9C18H20N2O3S
N-(2,3-Dimethyl-phenyl)-4-(pyrrolidine-1-sulfonyl)-benzamide chemical structure, C19H22N2O3S, CAS 392326-94-2
N-(2,3-Dimethyl-phenyl)-4-(pyrrolidine-1-sulfonyl)-benzamide
CAS 392326-94-2C19H22N2O3S
N-(2-Methoxyphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H20N2O4S, CAS 312755-78-5
N-(2-Methoxyphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 312755-78-5C18H20N2O4S
N-(3-Methoxy-phenyl)-4-(pyrrolidine-1-sulfonyl)-benzamide chemical structure, C18H20N2O4S, CAS 313528-66-4
N-(3-Methoxy-phenyl)-4-(pyrrolidine-1-sulfonyl)-benzamide
CAS 313528-66-4C18H20N2O4S
N-(4-Methoxyphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H20N2O4S, CAS 388623-00-5
N-(4-Methoxyphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 388623-00-5C18H20N2O4S
N-(4-Ethoxyphenyl)-4-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C19H22N2O4S, CAS 313549-74-5
N-(4-Ethoxyphenyl)-4-(pyrrolidine-1-sulfonyl)benzamide
CAS 313549-74-5C19H22N2O4S
Cambridge id 7149841 chemical structure, C19H22N2O4S, CAS 313646-32-1
Cambridge id 7149841
CAS 313646-32-1C19H22N2O4S
N-(3-Acetylphenyl)-4-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C19H20N2O4S, CAS 313404-05-6
N-(3-Acetylphenyl)-4-(pyrrolidine-1-sulfonyl)benzamide
CAS 313404-05-6C19H20N2O4S
N-(4-Iodophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C17H17IN2O3S, CAS 300826-60-2
N-(4-Iodophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 300826-60-2C17H17IN2O3S
4-(Pyrrolidin-1-ylsulfonyl)-N-(4-sulfamoylphenyl)benzamide chemical structure, C17H19N3O5S2, CAS 307327-12-4
4-(Pyrrolidin-1-ylsulfonyl)-N-(4-sulfamoylphenyl)benzamide
CAS 307327-12-4C17H19N3O5S2
N-{3-[(Difluoromethyl)sulfonyl]phenyl}-4-(1-pyrrolidinylsulfonyl)benzamide chemical structure, C18H18F2N2O5S2, CAS 690249-61-7
N-{3-[(Difluoromethyl)sulfonyl]phenyl}-4-(1-pyrrolidinylsulfonyl)benzamide
CAS 690249-61-7C18H18F2N2O5S2
N-(3,4-Dimethoxyphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H22N2O5S, CAS 750603-84-0
N-(3,4-Dimethoxyphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 750603-84-0C19H22N2O5S
N-(4-Bromophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C17H17BrN2O3S, CAS 313528-68-6
N-(4-Bromophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 313528-68-6C17H17BrN2O3S
N-(2,4-Difluorophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C17H16F2N2O3S, CAS 313528-79-9
N-(2,4-Difluorophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 313528-79-9C17H16F2N2O3S
N-(3,5-Dichlorophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C17H16Cl2N2O3S, CAS 313528-78-8
N-(3,5-Dichlorophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 313528-78-8C17H16Cl2N2O3S
N-(2-Chlorophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C17H17ClN2O3S, CAS 313403-51-9
N-(2-Chlorophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 313403-51-9C17H17ClN2O3S
N-(2-Methoxy-5-nitrophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C18H19N3O6S, CAS 325988-10-1
N-(2-Methoxy-5-nitrophenyl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 325988-10-1C18H19N3O6S
N-(2,5-Dichlorophenyl)-4-(1-pyrrolidinylsulfonyl)benzamide chemical structure, C17H16Cl2N2O3S, CAS 307338-81-4
N-(2,5-Dichlorophenyl)-4-(1-pyrrolidinylsulfonyl)benzamide
CAS 307338-81-4C17H16Cl2N2O3S
N-[2-(Difluoromethoxy)phenyl]-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C18H18F2N2O4S, CAS 848224-83-9
N-[2-(Difluoromethoxy)phenyl]-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 848224-83-9C18H18F2N2O4S
N-(3,5-Dimethylphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H22N2O3S, CAS 392251-71-7
N-(3,5-Dimethylphenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 392251-71-7C19H22N2O3S
N-(2-((2-Cyanoethyl)thio)phenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H21N3O3S2, CAS 397280-49-8
N-(2-((2-Cyanoethyl)thio)phenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 397280-49-8C20H21N3O3S2
N-(2-Cyanophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H17N3O3S, CAS 397280-27-2
N-(2-Cyanophenyl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 397280-27-2C18H17N3O3S