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Murcko scaffold

1-(Furan-2-carbonyl)-N-phenylpiperidine-4-carboxamide scaffold

37 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
37
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)C1CCN(C(=O)c2ccco2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Furan-2-carbonyl)-N-phenylpiperidine-4-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)C1CCN(C(=O)c2ccco2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

1-(Furan-2-carbonyl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide chemical structure, C18H17F3N2O3, CAS 887679-81-4
1-(Furan-2-carbonyl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide
CAS 887679-81-4C18H17F3N2O3
N-(4-Ethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H22N2O3, CAS 887680-90-2
N-(4-Ethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887680-90-2C19H22N2O3
N-(3-Chloro-4-methylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C18H19ClN2O3, CAS 878442-16-1
N-(3-Chloro-4-methylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-16-1C18H19ClN2O3
1-(Furan-2-carbonyl)-N-(4-methoxyphenyl)piperidine-4-carboxamide chemical structure, C18H20N2O4, CAS 878442-11-6
1-(Furan-2-carbonyl)-N-(4-methoxyphenyl)piperidine-4-carboxamide
CAS 878442-11-6C18H20N2O4
N-(3,5-Dimethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H22N2O3, CAS 887679-65-4
N-(3,5-Dimethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887679-65-4C19H22N2O3
N-(3-Fluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H17FN2O3, CAS 887679-97-2
N-(3-Fluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887679-97-2C17H17FN2O3
N-(3-Bromophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H17BrN2O3, CAS 887680-36-6
N-(3-Bromophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887680-36-6C17H17BrN2O3
N-(2,5-Dimethoxyphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H22N2O5, CAS 878442-14-9
N-(2,5-Dimethoxyphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-14-9C19H22N2O5
N-(3,4-Dimethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H22N2O3, CAS 887680-00-4
N-(3,4-Dimethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887680-00-4C19H22N2O3
1-(Furan-2-carbonyl)-N-(4-iodophenyl)piperidine-4-carboxamide chemical structure, C17H17IN2O3, CAS 887680-31-1
1-(Furan-2-carbonyl)-N-(4-iodophenyl)piperidine-4-carboxamide
CAS 887680-31-1C17H17IN2O3
N-(5-Chloro-2-methoxyphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C18H19ClN2O4, CAS 887680-27-5
N-(5-Chloro-2-methoxyphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887680-27-5C18H19ClN2O4
N-(2-Chlorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H17ClN2O3, CAS 878442-15-0
N-(2-Chlorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-15-0C17H17ClN2O3
N-(2-Fluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H17FN2O3, CAS 878442-08-1
N-(2-Fluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-08-1C17H17FN2O3
N-(2,4-Dimethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H22N2O3, CAS 887681-05-2
N-(2,4-Dimethylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887681-05-2C19H22N2O3
N-(4-Bromo-2-fluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H16BrFN2O3, CAS 878442-12-7
N-(4-Bromo-2-fluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-12-7C17H16BrFN2O3
1-(Furan-2-carbonyl)-N-phenylpiperidine-4-carboxamide chemical structure, C17H18N2O3, CAS 887679-74-5
1-(Furan-2-carbonyl)-N-phenylpiperidine-4-carboxamide
CAS 887679-74-5C17H18N2O3
N-(3-Chloro-2-methylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C18H19ClN2O3, CAS 878442-13-8
N-(3-Chloro-2-methylphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-13-8C18H19ClN2O3
N-(4-Chloro-2,5-dimethoxyphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H21ClN2O5, CAS 878442-18-3
N-(4-Chloro-2,5-dimethoxyphenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 878442-18-3C19H21ClN2O5
1-(Furan-2-carbonyl)-N-(2-propan-2-ylphenyl)piperidine-4-carboxamide chemical structure, C20H24N2O3, CAS 887680-19-5
1-(Furan-2-carbonyl)-N-(2-propan-2-ylphenyl)piperidine-4-carboxamide
CAS 887680-19-5C20H24N2O3
N-(3-Acetamidophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C19H21N3O4, CAS 887680-68-4
N-(3-Acetamidophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887680-68-4C19H21N3O4
1-(Furan-2-carbonyl)-N-(4-methylphenyl)piperidine-4-carboxamide chemical structure, C18H20N2O3, CAS 887680-46-8
1-(Furan-2-carbonyl)-N-(4-methylphenyl)piperidine-4-carboxamide
CAS 887680-46-8C18H20N2O3
N-(4-Cyanophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C18H17N3O3, CAS 887681-30-3
N-(4-Cyanophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887681-30-3C18H17N3O3
N-(2,4-Difluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H16F2N2O3, CAS 887680-76-4
N-(2,4-Difluorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887680-76-4C17H16F2N2O3
N-(2,4-Dichlorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide chemical structure, C17H16Cl2N2O3, CAS 887681-15-4
N-(2,4-Dichlorophenyl)-1-(furan-2-carbonyl)piperidine-4-carboxamide
CAS 887681-15-4C17H16Cl2N2O3