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Murcko scaffold

1-(2-Oxo-2-pyrrolidin-1-ylethyl)-1H-indole scaffold

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
48
With full pages
4
Scaffold SMILES

O=C(Cn1ccc2ccccc21)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Oxo-2-pyrrolidin-1-ylethyl)-1H-indole page
Murcko scaffold O=C(Cn1ccc2ccccc21)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

Pyrrolidine, 1-((2-methyl-1H-indol-1-yl)acetyl)- chemical structure, C15H18N2O, CAS 163629-09-2
Pyrrolidine, 1-((2-methyl-1H-indol-1-yl)acetyl)-
CAS 163629-09-2C15H18N2O
1-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-1H-indole-3-carbaldehyde chemical structure, C15H16N2O2, CAS 347320-40-5
1-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-1H-indole-3-carbaldehyde
CAS 347320-40-5C15H16N2O2
5-Bromo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indole-3-carbaldehyde chemical structure, C15H15BrN2O2, CAS 434299-46-4
5-Bromo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indole-3-carbaldehyde
CAS 434299-46-4C15H15BrN2O2
1-(2-Oxo-2-pyrrolidin-1-ylethyl)indole-3-carbonitrile chemical structure, C15H15N3O, CAS 347321-96-4
1-(2-Oxo-2-pyrrolidin-1-ylethyl)indole-3-carbonitrile
CAS 347321-96-4C15H15N3O
2-Methyl-1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-1H-indole-3-carbaldehyde chemical structure, C16H18N2O2, CAS 431910-43-9
2-Methyl-1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-1H-indole-3-carbaldehyde
CAS 431910-43-9C16H18N2O2
7-Ethyl-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indole-3-carbaldehyde chemical structure, C17H20N2O2, CAS 593237-24-2
7-Ethyl-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indole-3-carbaldehyde
CAS 593237-24-2C17H20N2O2
2-(3-Acetylindol-1-yl)-1-pyrrolidin-1-ylethanone chemical structure, C16H18N2O2, CAS 799264-64-5
2-(3-Acetylindol-1-yl)-1-pyrrolidin-1-ylethanone
CAS 799264-64-5C16H18N2O2
N,N-Diethyl-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C20H25N3O3, CAS 831241-01-1
N,N-Diethyl-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 831241-01-1C20H25N3O3
N-Methyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C17H19N3O3, CAS 872848-85-6
N-Methyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-85-6C17H19N3O3
N-Ethyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C18H21N3O3, CAS 872848-86-7
N-Ethyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-86-7C18H21N3O3
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-propylacetamide chemical structure, C19H23N3O3, CAS 872848-87-8
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-propylacetamide
CAS 872848-87-8C19H23N3O3
N-Butyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C20H25N3O3, CAS 872848-88-9
N-Butyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-88-9C20H25N3O3
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-propan-2-ylacetamide chemical structure, C19H23N3O3, CAS 872848-89-0
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-propan-2-ylacetamide
CAS 872848-89-0C19H23N3O3
N-(2-Methylpropyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C20H25N3O3, CAS 872848-90-3
N-(2-Methylpropyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-90-3C20H25N3O3
N-Butan-2-yl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C20H25N3O3, CAS 872848-91-4
N-Butan-2-yl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-91-4C20H25N3O3
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-prop-2-enylacetamide chemical structure, C19H21N3O3, CAS 872848-93-6
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N-prop-2-enylacetamide
CAS 872848-93-6C19H21N3O3
N-(3-Methylbutyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C21H27N3O3, CAS 872848-94-7
N-(3-Methylbutyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-94-7C21H27N3O3
N-(3-Methoxypropyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C20H25N3O4, CAS 872848-96-9
N-(3-Methoxypropyl)-2-oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872848-96-9C20H25N3O4
1-(2-Oxo-2-pyrrolidin-1-ylethyl)-1H-indole chemical structure, C14H16N2O, CAS 676644-16-9
1-(2-Oxo-2-pyrrolidin-1-ylethyl)-1H-indole
CAS 676644-16-9C14H16N2O
2-Oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C16H17N3O3, CAS 872854-95-0
2-Oxo-2-{1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872854-95-0C16H17N3O3
N-Methyl-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]sulfonylacetamide chemical structure, C17H21N3O4S, CAS 878058-02-7
N-Methyl-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]sulfonylacetamide
CAS 878058-02-7C17H21N3O4S
N,N-Dimethyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C18H21N3O3, CAS 872848-77-6
N,N-Dimethyl-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide
CAS 872848-77-6C18H21N3O3
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N,N-di(propan-2-yl)acetamide chemical structure, C22H29N3O3, CAS 872848-78-7
2-Oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]-N,N-di(propan-2-yl)acetamide
CAS 872848-78-7C22H29N3O3
N-(3-(Dimethylamino)propyl)-2-oxo-2-(1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indol-3-yl)acetamide chemical structure, C21H28N4O3, CAS 893990-35-7
N-(3-(Dimethylamino)propyl)-2-oxo-2-(1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indol-3-yl)acetamide
CAS 893990-35-7C21H28N4O3