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Murcko scaffold

Ring system with 2 rings and 17 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
19
With full pages
2
Scaffold SMILES

O=C1CCC(C(=O)NCC(=O)N2CCCC2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(C(=O)NCC(=O)N2CCCC2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

Pyroglutamyl-glutamyl-proline amide chemical structure, C15H22N4O6, CAS 85541-78-2
Pyroglutamyl-glutamyl-proline amide
CAS 85541-78-2C15H22N4O6
Thyrotropin-releasing hormone, nVal(2)- chemical structure, C15H24N4O4, CAS 78058-02-3
Thyrotropin-releasing hormone, nVal(2)-
CAS 78058-02-3C15H24N4O4
5-Oxo-L-prolyl-L-leucyl-L-prolinamide chemical structure, C16H26N4O4, CAS 49760-92-1
5-Oxo-L-prolyl-L-leucyl-L-prolinamide
CAS 49760-92-1C16H26N4O4
[Val2]TRH chemical structure, C15H24N4O4, CAS 78058-07-8
[Val2]TRH
CAS 78058-07-8C15H24N4O4
L-Proline, 1-[N-(5-oxo-L-prolyl)-L-leucyl]- chemical structure, C16H25N3O5, CAS 85146-12-9
L-Proline, 1-[N-(5-oxo-L-prolyl)-L-leucyl]-
CAS 85146-12-9C16H25N3O5
L-Prolinamide, 5-oxo-L-prolyl-L-lysyl- chemical structure, C16H27N5O4, CAS 32467-84-8
L-Prolinamide, 5-oxo-L-prolyl-L-lysyl-
CAS 32467-84-8C16H27N5O4
L-Prolinamide, 5-oxo-L-prolyl-L-seryl- chemical structure, C13H20N4O5, CAS 63155-77-1
L-Prolinamide, 5-oxo-L-prolyl-L-seryl-
CAS 63155-77-1C13H20N4O5
5-Oxo-L-prolyl-D-leucyl-L-prolinamide chemical structure, C16H26N4O4, CAS 78058-30-7
5-Oxo-L-prolyl-D-leucyl-L-prolinamide
CAS 78058-30-7C16H26N4O4
5-Oxo-L-prolyl-L-leucyl-D-prolinamide chemical structure, C16H26N4O4, CAS 78664-40-1
5-Oxo-L-prolyl-L-leucyl-D-prolinamide
CAS 78664-40-1C16H26N4O4
5-Oxo-D-prolyl-L-leucyl-L-prolinamide chemical structure, C16H26N4O4, CAS 78664-76-3
5-Oxo-D-prolyl-L-leucyl-L-prolinamide
CAS 78664-76-3C16H26N4O4
5-Oxo-L-prolyl-L-leucyl-N-ethyl-L-prolinamide chemical structure, C18H30N4O4, CAS 78058-34-1
5-Oxo-L-prolyl-L-leucyl-N-ethyl-L-prolinamide
CAS 78058-34-1C18H30N4O4
5-Oxo-L-prolyl-L-leucyl-N-decyl-L-prolinamide chemical structure, C26H46N4O4, CAS 78058-37-4
5-Oxo-L-prolyl-L-leucyl-N-decyl-L-prolinamide
CAS 78058-37-4C26H46N4O4
5-Oxo-L-prolyl-L-leucyl-N-[2-(dimethylamino)ethyl]-L-prolinamide chemical structure, C20H35N5O4, CAS 78058-38-5
5-Oxo-L-prolyl-L-leucyl-N-[2-(dimethylamino)ethyl]-L-prolinamide
CAS 78058-38-5C20H35N5O4
5-Oxo-L-prolyl-L-isoleucyl-L-prolinamide chemical structure, C16H26N4O4, CAS 78058-11-4
5-Oxo-L-prolyl-L-isoleucyl-L-prolinamide
CAS 78058-11-4C16H26N4O4
5-Oxo-L-prolyl-L-threonyl-L-prolinamide chemical structure, C14H22N4O5, CAS 78058-24-9
5-Oxo-L-prolyl-L-threonyl-L-prolinamide
CAS 78058-24-9C14H22N4O5
5-Oxo-L-prolyl-L-methionyl-L-prolinamide chemical structure, C15H24N4O4S, CAS 35259-10-0
5-Oxo-L-prolyl-L-methionyl-L-prolinamide
CAS 35259-10-0C15H24N4O4S
5-Oxo-L-prolylglycyl-L-proline chemical structure, C12H17N3O5, CAS 47071-00-1
5-Oxo-L-prolylglycyl-L-proline
CAS 47071-00-1C12H17N3O5
5-Oxo-L-prolylglycyl-L-prolinamide chemical structure, C12H18N4O4, CAS 42294-01-9
5-Oxo-L-prolylglycyl-L-prolinamide
CAS 42294-01-9C12H18N4O4
5-Oxo-L-prolyl-L-isoleucyl-L-proline chemical structure, C16H25N3O5, CAS 85541-63-5
5-Oxo-L-prolyl-L-isoleucyl-L-proline
CAS 85541-63-5C16H25N3O5