Murcko scaffold
Ring system with 2 rings and 16 atoms
69 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 69
- With full pages
- 5
Scaffold SMILES
O=C(NCC(=O)N1CCCC1)C1CCCN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 69 chemicals
Glycyl-prolyl-arginyl-proline
CAS 67869-62-9C18H31N7O5
Preprovasoactive intestinal peptide (111-122)
CAS 123025-94-5C53H87N13O21
Substance P (1-4)
CAS 69355-89-1C22H41N9O4
Enterostatin
CAS 117830-79-2C21H36N8O6
Pro-Thr-Pro-Ser amide
C17H29N5O6
Somatrem
CAS 82030-87-3C43H72N14O14
P15 peptide
CAS 134335-45-8C59H100N20O19
Prolyl-glycyl-proline
CAS 7561-51-5C12H19N3O4
VPGPR Enterostatin
CAS 144964-56-7C23H40N8O6
Valyl-prolyl-aspartyl-prolyl-arginine
CAS 117137-85-6C25H42N8O8
Lys-Val-Leu-Pro-Val-Pro-Gln
CAS 178913-61-6C37H65N9O9
H-Gly-Pro-Arg-Pro-NH2
CAS 126047-75-4C18H32N8O4
Substance P (1-6)
CAS 68232-52-0C32H56N12O9
L-Alaninamide, 1-acetyl-L-prolyl-L-alanyl-L-prolyl-
CAS 30802-34-7C18H29N5O5
H-Ala-Pro-Gly-Pro-Ser-Lys-Ser-OH
CAS 498565-49-4C27H46N8O10
Substance P(1-4)
CAS 57468-16-3C22H40N8O5
Pentapeptide-3
CAS 135679-88-8C21H37N9O5
L-Proline, L-prolyl-L-arginyl-
CAS 56610-49-2C16H28N6O4
H-Pvp-OH
CAS 178913-70-7C15H25N3O4
1-(Carboxymethyl)-L-prolyl-L-alanyl-L-proline
CAS 87297-12-9C15H23N3O6
1-(Carboxymethyl)-L-prolyl-D-alanyl-L-proline
CAS 87297-41-4C15H23N3O6
1-(2-Carboxyethyl)-L-prolyl-L-alanyl-L-proline
CAS 87297-27-6C16H25N3O6
1-(2-Carboxyethyl)-L-prolyl-D-alanyl-L-proline
CAS 87297-42-5C16H25N3O6
N~5~-(Diaminomethylidene)ornithylprolyllysylproline
C22H40N8O5
- Acetylprolylalanylproline41036-61-7C15H23N3O5
- P-T-P-S-NH2121269-85-0C17H29N5O6
- Glycyl-L-prolyl-L-isoleucyl-L-prolyl-L-asparagine863015-17-2C22H36N6O7
- N~5~-(Diaminomethylidene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-proline776334-69-1C22H40N10O5
- 39 suppliersAlkaline phosphatase9001-78-9C21H36N8O6
- L-Valyl-L-leucyl-L-prolyl-L-valyl-L-prolyl-L-glutamine178913-65-0C31H53N7O8
- L-Lysyl-L-valyl-L-leucyl-L-prolyl-L-valyl-L-proline178913-72-9C32H57N7O7
- L-Prolyl-L-seryl-L-proline849599-30-0C13H21N3O5
- H2N-Ktllptp-OH1192023-11-2C36H64N8O10
- Ac-Pro-Gly-Pro-OH292171-04-1C14H21N3O5
- H-Met-lys-arg-ser-arg-gly-pro-ser-pro-arg-arg-OH165174-60-7C53H98N24O14S
- L-Prolyl-L-leucyl-L-prolyl-L-valyl-L-threonyl-L-aspartic acid194658-64-5C29H48N6O10
- Glycyl-L-prolyl-L-isoleucyl-L-proline192520-55-1C18H30N4O5
- L-Valyl-L-seryl-L-lysyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-proline189457-06-5C36H66N14O9
- L-Alanyl-L-prolylglycyl-L-proline160489-02-1C15H24N4O5
- N~5~-(Diaminomethylidene)-L-ornithyl-L-prolyl-L-alanyl-L-prolylglycyl-L-serine157414-49-8C24H41N9O8
- Glycyl-L-prolyl-L-alanyl-L-prolyl-L-threonine195870-56-5C19H31N5O7
- L-Seryl-L-prolyl-L-isoleucyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithine187722-33-4C25H44N8O7
- H-Gly-Pro-Arg-Pro-Ser-NH2139362-41-7C21H37N9O6
- L-Prolyl-L-alanyl-L-prolyl-L-alanine210840-24-7C16H26N4O5
- N~5~-(Diaminomethylidene)-L-ornithyl-L-prolylglycyl-L-proline396080-59-4C18H31N7O5
- L-Lysyl-L-valyl-L-leucyl-L-prolyl-L-valyl-L-prolyl-L-glutaminyl-L-lysine325455-70-7C43H77N11O10
- L-Prolylglycyl-L-prolylglycylglycine407577-26-8C16H25N5O6
- D-Lysyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-proline674303-32-3C22H40N8O5
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nnc[nH]1)Nc1nccs1](/scaffold/COYLJWMIPKCUCN-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnc[nH]1)Nc1nccs16 chemicals
O=C(C=Cc1ccco1)Nc1cccs15 chemicals
O=C(NN=Cc1ccco1)c1ccsc15 chemicals![Scaffold O=C(NN=Cc1ccco1)c1cc[nH]n1](/scaffold/FSXZXXXMFAXQTH-UHFFFAOYSA-N/structure.svg)
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O=C(Cn1cccn1)NCC1CCCO14 chemicals
O=C(C=Cc1ccco1)Nc1nncs14 chemicals![Scaffold O=C(CSc1nnc[nH]1)NC1CCCC1](/scaffold/ULWZQPJKAQNAKP-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnc[nH]1)NC1CCCC14 chemicals
O=C(NN=Cc1cccs1)c1cccs13 chemicals
O=C(NN=Cc1cccs1)c1ccsc13 chemicals![Scaffold O=C(NN=Cc1cccs1)c1cc[nH]n1](/scaffold/GNPNMVVRCFZHEL-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1cccs1)c1cc[nH]n13 chemicals
O=C(C=Cc1cccs1)Nc1nccs13 chemicals
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