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Murcko scaffold

Ring system with 2 rings and 15 atoms

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
15
With full pages
5
Scaffold SMILES

O=C(C=Cc1ccco1)Nc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccco1)Nc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

(E)-Ethyl 2-(3-(furan-2-yl)acrylamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C16H17NO4S, CAS 1164519-89-4
(E)-Ethyl 2-(3-(furan-2-yl)acrylamido)-4,5-dimethylthiophene-3-carboxylate
CAS 1164519-89-4C16H17NO4S
Methyl 2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-4,5-dimethylthiophene-3-carboxylate chemical structure, C15H15NO4S, CAS 419560-00-2
Methyl 2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-4,5-dimethylthiophene-3-carboxylate
CAS 419560-00-2C15H15NO4S
Methyl 4,5-dimethyl-2-[[(E)-3-(5-methyl-2-furyl)prop-2-enoyl]amino]thiophene-3-carboxylate chemical structure, C16H17NO4S, CAS 5704-37-0
Methyl 4,5-dimethyl-2-[[(E)-3-(5-methyl-2-furyl)prop-2-enoyl]amino]thiophene-3-carboxylate
CAS 5704-37-0C16H17NO4S
Dimethyl 5-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-3-methylthiophene-2,4-dicarboxylate chemical structure, C16H15NO6S, CAS 420094-65-1
Dimethyl 5-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-3-methylthiophene-2,4-dicarboxylate
CAS 420094-65-1C16H15NO6S
Ethyl 4,5-dimethyl-2-{[3-(5-methyl-2-furyl)acryloyl]amino}-3-thiophenecarboxylate chemical structure, C17H19NO4S, CAS 1164507-14-5
Ethyl 4,5-dimethyl-2-{[3-(5-methyl-2-furyl)acryloyl]amino}-3-thiophenecarboxylate
CAS 1164507-14-5C17H19NO4S
Isopropyl 4,5-dimethyl-2-{[3-(5-methyl-2-furyl)acryloyl]amino}-3-thiophenecarboxylate chemical structure, C18H21NO4S, CAS 1164479-38-2
Isopropyl 4,5-dimethyl-2-{[3-(5-methyl-2-furyl)acryloyl]amino}-3-thiophenecarboxylate
CAS 1164479-38-2C18H21NO4S
Isopropyl 2-{[3-(2-furyl)acryloyl]amino}-4,5-dimethyl-3-thiophenecarboxylate chemical structure, C17H19NO4S, CAS 1164533-70-3
Isopropyl 2-{[3-(2-furyl)acryloyl]amino}-4,5-dimethyl-3-thiophenecarboxylate
CAS 1164533-70-3C17H19NO4S
4-Ethyl-5-methyl-2-[3-(5-methylfuran-2-yl)prop-2-enoylamino]thiophene-3-carboxamide chemical structure, C16H18N2O3S, CAS 4437-48-3
4-Ethyl-5-methyl-2-[3-(5-methylfuran-2-yl)prop-2-enoylamino]thiophene-3-carboxamide
CAS 4437-48-3C16H18N2O3S
(E)-Methyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C16H14N2O4S, CAS 468749-10-2
(E)-Methyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4,5-dimethylthiophene-3-carboxylate
CAS 468749-10-2C16H14N2O4S
Isopropyl 5-[(diethylamino)carbonyl]-2-{[3-(2-furyl)acryloyl]amino}-4-methyl-3-thiophenecarboxylate chemical structure, C21H26N2O5S, CAS 543716-56-9
Isopropyl 5-[(diethylamino)carbonyl]-2-{[3-(2-furyl)acryloyl]amino}-4-methyl-3-thiophenecarboxylate
CAS 543716-56-9C21H26N2O5S
Ethyl 4-ethyl-2-[(3-{5-nitro-2-furyl}acryloyl)amino]-5-methyl-3-thiophenecarboxylate chemical structure, C17H18N2O6S, CAS 514842-54-7
Ethyl 4-ethyl-2-[(3-{5-nitro-2-furyl}acryloyl)amino]-5-methyl-3-thiophenecarboxylate
CAS 514842-54-7C17H18N2O6S
4-Ethyl 2-methyl 5-{[(2E)-3-(furan-2-yl)prop-2-enoyl]amino}-3-methylthiophene-2,4-dicarboxylate chemical structure, C17H17NO6S, CAS 433707-78-9
4-Ethyl 2-methyl 5-{[(2E)-3-(furan-2-yl)prop-2-enoyl]amino}-3-methylthiophene-2,4-dicarboxylate
CAS 433707-78-9C17H17NO6S
Propan-2-yl 4-carbamoyl-5-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-3-methylthiophene-2-carboxylate chemical structure, C17H18N2O5S, CAS 419558-82-0
Propan-2-yl 4-carbamoyl-5-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-3-methylthiophene-2-carboxylate
CAS 419558-82-0C17H18N2O5S
(E)-Diethyl 5-(3-(furan-2-yl)acrylamido)-3-methylthiophene-2,4-dicarboxylate chemical structure, C18H19NO6S, CAS 299953-33-6
(E)-Diethyl 5-(3-(furan-2-yl)acrylamido)-3-methylthiophene-2,4-dicarboxylate
CAS 299953-33-6C18H19NO6S
(E)-Methyl 2-(2-cyano-3-(5-methylfuran-2-yl)acrylamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C17H16N2O4S, CAS 468749-11-3
(E)-Methyl 2-(2-cyano-3-(5-methylfuran-2-yl)acrylamido)-4,5-dimethylthiophene-3-carboxylate
CAS 468749-11-3C17H16N2O4S