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Murcko scaffold

Ring system with 2 rings and 15 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
14
With full pages
6
Scaffold SMILES

O=C(CSc1nnc[nH]1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc[nH]1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-(4-Methyl-1,3-thiazol-2-yl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C9H11N5OS2, CAS 725706-82-1
N-(4-Methyl-1,3-thiazol-2-yl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 725706-82-1C9H11N5OS2
2-[(4,5-Dimethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide chemical structure, C9H11N5OS2, CAS 626226-78-6
2-[(4,5-Dimethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
CAS 626226-78-6C9H11N5OS2
Ethyl 4-methyl-2-({[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}amino)-1,3-thiazole-5-carboxylate chemical structure, C12H15N5O3S2, CAS 433316-10-0
Ethyl 4-methyl-2-({[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetyl}amino)-1,3-thiazole-5-carboxylate
CAS 433316-10-0C12H15N5O3S2
2-[(4-Ethyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)propanamide chemical structure, C11H15N5OS2, CAS 892670-31-4
2-[(4-Ethyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)propanamide
CAS 892670-31-4C11H15N5OS2
2-[(4,5-Diethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H17N5OS2, CAS 892670-99-4
2-[(4,5-Diethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 892670-99-4C12H17N5OS2
2-[(5-Ethyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)propanamide chemical structure, C11H15N5OS2, CAS 892670-73-4
2-[(5-Ethyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)propanamide
CAS 892670-73-4C11H15N5OS2
N,N,4-trimethyl-2-[[2-[(5-methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]-1,3-thiazole-5-carboxamide chemical structure, C15H20N6O2S2, CAS 900593-20-6
N,N,4-trimethyl-2-[[2-[(5-methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]-1,3-thiazole-5-carboxamide
CAS 900593-20-6C15H20N6O2S2
2-[(5-Methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H13N5OS2, CAS 899019-37-5
2-[(5-Methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
CAS 899019-37-5C11H13N5OS2
Methyl 2-[2-[[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]-1,3-thiazol-4-yl]acetate chemical structure, C11H13N5O3S2, CAS 874965-81-8
Methyl 2-[2-[[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]-1,3-thiazol-4-yl]acetate
CAS 874965-81-8C11H13N5O3S2
2-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)butanamide chemical structure, C10H13N5OS2, CAS 924973-78-4
2-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)butanamide
CAS 924973-78-4C10H13N5OS2
2-{[5-Ethyl-4-(2-methylpropyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide chemical structure, C13H19N5OS2, CAS 924978-83-6
2-{[5-Ethyl-4-(2-methylpropyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide
CAS 924978-83-6C13H19N5OS2
2-[(4,5-Dimethyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C10H13N5OS2, CAS 951995-30-5
2-[(4,5-Dimethyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 951995-30-5C10H13N5OS2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-[(4,5-dimethyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C13H19N5OS2, CAS 948153-45-5
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-[(4,5-dimethyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 948153-45-5C13H19N5OS2
2-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)propanamide chemical structure, C9H11N5OS2, CAS 1226806-57-0
2-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)propanamide
CAS 1226806-57-0C9H11N5OS2