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Murcko scaffold

4,5-Diphenyl-1,3-thiazole scaffold

53 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
53
With full pages
11
Scaffold SMILES

c1ccc(-c2ncsc2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,5-Diphenyl-1,3-thiazole page
Murcko scaffold c1ccc(-c2ncsc2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

Itazigrel chemical structure, C18H14F3NO2S, CAS 70529-35-0
Itazigrel
CAS 70529-35-0C18H14F3NO2S
2-Amino-4,5-diphenylthiazole chemical structure, C15H12N2S, CAS 6318-74-7
2-Amino-4,5-diphenylthiazole
CAS 6318-74-7C15H12N2S
2-Methyl-4,5-diphenylthiazole chemical structure, C16H13NS, CAS 3755-83-7
2-Methyl-4,5-diphenylthiazole
CAS 3755-83-7C16H13NS
Diphenyl-1,3-thiazol-2-amine hydrochloride chemical structure, C15H13ClN2S, CAS 36761-88-3
Diphenyl-1,3-thiazol-2-amine hydrochloride
CAS 36761-88-3C15H13ClN2S
2-Thiazolamine, 4-(4-methoxyphenyl)-5-phenyl- chemical structure, C16H14N2OS, CAS 91069-96-4
2-Thiazolamine, 4-(4-methoxyphenyl)-5-phenyl-
CAS 91069-96-4C16H14N2OS
4,5-Diphenyl-1,3-thiazole chemical structure, C15H11NS, CAS 1826-15-9
4,5-Diphenyl-1,3-thiazole
CAS 1826-15-9C15H11NS
N-(4,5-Bis(4-methoxyphenyl)-2-thiazolyl)acetamide chemical structure, C19H18N2O3S, CAS 24827-47-2
N-(4,5-Bis(4-methoxyphenyl)-2-thiazolyl)acetamide
CAS 24827-47-2C19H18N2O3S
4,5-Bis-(4-methoxy-phenyl)-thiazol-2-ylamine chemical structure, C17H16N2O2S, CAS 24827-38-1
4,5-Bis-(4-methoxy-phenyl)-thiazol-2-ylamine
CAS 24827-38-1C17H16N2O2S
5-Phenyl-4-(p-tolyl)thiazol-2-amine chemical structure, C16H14N2S, CAS 75745-30-1
5-Phenyl-4-(p-tolyl)thiazol-2-amine
CAS 75745-30-1C16H14N2S
N-(4,5-Diphenyl-1,3-thiazol-2-yl)propanamide chemical structure, C18H16N2OS, CAS 313660-07-0
N-(4,5-Diphenyl-1,3-thiazol-2-yl)propanamide
CAS 313660-07-0C18H16N2OS
(Z)-N-(4,5-Diphenylthiazol-2(3H)-ylidene)isobutyramide chemical structure, C19H18N2OS, CAS 313660-08-1
(Z)-N-(4,5-Diphenylthiazol-2(3H)-ylidene)isobutyramide
CAS 313660-08-1C19H18N2OS
Bis(2-chlorophenyl)-1,3-thiazol-2-amine chemical structure, C15H10Cl2N2S, CAS 89405-44-7
Bis(2-chlorophenyl)-1,3-thiazol-2-amine
CAS 89405-44-7C15H10Cl2N2S
4,5-Di-p-tolyl-thiazol-2-ylamine chemical structure, C17H16N2S, CAS 102026-45-9
4,5-Di-p-tolyl-thiazol-2-ylamine
CAS 102026-45-9C17H16N2S
N-[4,5-Bis-(2-chloro-phenyl)-thiazol-2-yl]-2-chloro-acetamide chemical structure, C17H11Cl3N2OS, CAS 748792-97-4
N-[4,5-Bis-(2-chloro-phenyl)-thiazol-2-yl]-2-chloro-acetamide
CAS 748792-97-4C17H11Cl3N2OS
N-[Bis(4-tert-butylphenyl)-1,3-thiazol-2-yl]-2-chloroacetamide chemical structure, C25H29ClN2OS, CAS 554404-35-2
N-[Bis(4-tert-butylphenyl)-1,3-thiazol-2-yl]-2-chloroacetamide
CAS 554404-35-2C25H29ClN2OS
Bis(4-tert-butylphenyl)-1,3-thiazol-2-amine chemical structure, C23H28N2S, CAS 554405-20-8
Bis(4-tert-butylphenyl)-1,3-thiazol-2-amine
CAS 554405-20-8C23H28N2S
4,5-Bis(4-methoxyphenyl)-N-methyl-1,3-thiazol-2-amine chemical structure, C18H18N2O2S, CAS 796115-98-5
4,5-Bis(4-methoxyphenyl)-N-methyl-1,3-thiazol-2-amine
CAS 796115-98-5C18H18N2O2S
3-Ethyl-2-methyl-4,5-diphenyl-1,3-thiazol-3-ium perchlorate chemical structure, C18H18ClNO4S
3-Ethyl-2-methyl-4,5-diphenyl-1,3-thiazol-3-ium perchlorate
C18H18ClNO4S
3-Ethyl-2-methyl-4,5-diphenyl-1,3-thiazol-3-ium chemical structure, C18H18NS+, CAS 119953-89-8
3-Ethyl-2-methyl-4,5-diphenyl-1,3-thiazol-3-ium
CAS 119953-89-8C18H18NS+
N-[4-(4-Methylphenyl)-5-phenyl-1,3-thiazol-2-yl]propanamide chemical structure, C19H18N2OS, CAS 313374-87-7
N-[4-(4-Methylphenyl)-5-phenyl-1,3-thiazol-2-yl]propanamide
CAS 313374-87-7C19H18N2OS
5-(4-Methoxyphenyl)-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H14N2OS, CAS 121244-35-7
5-(4-Methoxyphenyl)-4-phenyl-1,3-thiazol-2-amine
CAS 121244-35-7C16H14N2OS
N-[4,5-Bis(4-methylphenyl)-1,3-thiazol-2-yl]-2-chloroacetamide chemical structure, C19H17ClN2OS, CAS 726157-04-6
N-[4,5-Bis(4-methylphenyl)-1,3-thiazol-2-yl]-2-chloroacetamide
CAS 726157-04-6C19H17ClN2OS
N-(4,5-Diphenyl-1,3-thiazol-2-yl)butanamide chemical structure, C19H18N2OS, CAS 476285-62-8
N-(4,5-Diphenyl-1,3-thiazol-2-yl)butanamide
CAS 476285-62-8C19H18N2OS
N'-(4,5-Diphenyl-1,3-thiazol-2-yl)-N,N-dimethylmethanimidamide chemical structure, C18H17N3S
N'-(4,5-Diphenyl-1,3-thiazol-2-yl)-N,N-dimethylmethanimidamide
C18H17N3S