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Murcko scaffold

Cyclopropyl(pyrrolidin-1-yl)methanone scaffold

57 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
57
With full pages
2
Scaffold SMILES

O=C(C1CC1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Cyclopropyl(pyrrolidin-1-yl)methanone page
Murcko scaffold O=C(C1CC1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 57 chemicals

Cyclopropyl(pyrrolidin-1-yl)methanone chemical structure, C8H13NO, CAS 540802-37-7
Cyclopropyl(pyrrolidin-1-yl)methanone
CAS 540802-37-7C8H13NO
(S)-1-(Cyclopropanecarbonyl)pyrrolidine-2-carboxylic acid chemical structure, C9H13NO3, CAS 148706-15-4
(S)-1-(Cyclopropanecarbonyl)pyrrolidine-2-carboxylic acid
CAS 148706-15-4C9H13NO3
1-(Pyrrolidine-1-carbonyl)cyclopropanecarbonitrile chemical structure, C9H12N2O, CAS 602303-01-5
1-(Pyrrolidine-1-carbonyl)cyclopropanecarbonitrile
CAS 602303-01-5C9H12N2O
1-Cyclopropanecarbonylpyrrolidine-2-carboxylic acid chemical structure, C9H13NO3, CAS 1344953-31-6
1-Cyclopropanecarbonylpyrrolidine-2-carboxylic acid
CAS 1344953-31-6C9H13NO3
1-(Pyrrolidine-1-carbonyl)cyclopropane-1-carboxamide chemical structure, C9H14N2O2, CAS 1001345-82-9
1-(Pyrrolidine-1-carbonyl)cyclopropane-1-carboxamide
CAS 1001345-82-9C9H14N2O2
2,2-Dimethyl-3-(pyrrolidin-1-ylcarbonyl)-cyclopropanecarboxylic acid chemical structure, C11H17NO3, CAS 1142214-97-8
2,2-Dimethyl-3-(pyrrolidin-1-ylcarbonyl)-cyclopropanecarboxylic acid
CAS 1142214-97-8C11H17NO3
[(2S)-1-Cyclopropanecarbonylpyrrolidin-2-yl]methanol chemical structure, C9H15NO2, CAS 1177999-84-6
[(2S)-1-Cyclopropanecarbonylpyrrolidin-2-yl]methanol
CAS 1177999-84-6C9H15NO2
(R)-1-(Cyclopropanecarbonyl)pyrrolidine-2-carboxylic acid chemical structure, C9H13NO3
(R)-1-(Cyclopropanecarbonyl)pyrrolidine-2-carboxylic acid
C9H13NO3
((1R,2R)-2-Methylcyclopropyl)(pyrrolidin-1-yl)methanone chemical structure, C9H15NO, CAS 90985-55-0
((1R,2R)-2-Methylcyclopropyl)(pyrrolidin-1-yl)methanone
CAS 90985-55-0C9H15NO
(2S)-1-(Cyclopropanecarbonyl)pyrrolidine-2-carboxamide chemical structure, C9H14N2O2, CAS 66158-60-9
(2S)-1-(Cyclopropanecarbonyl)pyrrolidine-2-carboxamide
CAS 66158-60-9C9H14N2O2
(S)-tert-Butyl 1-(cyclopropanecarbonyl)pyrrolidin-3-ylcarbamate chemical structure, C13H22N2O3, CAS 1286209-11-7
(S)-tert-Butyl 1-(cyclopropanecarbonyl)pyrrolidin-3-ylcarbamate
CAS 1286209-11-7C13H22N2O3
(S)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone hydrochloride chemical structure, C8H15ClN2O, CAS 1286207-03-1
(S)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone hydrochloride
CAS 1286207-03-1C8H15ClN2O
(S)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone chemical structure, C8H14N2O, CAS 1286317-23-4
(S)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone
CAS 1286317-23-4C8H14N2O
(R)-tert-Butyl 1-(cyclopropanecarbonyl)pyrrolidin-3-ylcarbamate chemical structure, C13H22N2O3, CAS 1286207-02-0
(R)-tert-Butyl 1-(cyclopropanecarbonyl)pyrrolidin-3-ylcarbamate
CAS 1286207-02-0C13H22N2O3
(R)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone hydrochloride chemical structure, C8H15ClN2O, CAS 1286207-68-8
(R)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone hydrochloride
CAS 1286207-68-8C8H15ClN2O
(R)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone chemical structure, C8H14N2O, CAS 1286317-39-2
(R)-(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone
CAS 1286317-39-2C8H14N2O
1-Cyclopropanecarbonylpyrrolidine-2-carbaldehyde chemical structure, C9H13NO2, CAS 1082383-02-5
1-Cyclopropanecarbonylpyrrolidine-2-carbaldehyde
CAS 1082383-02-5C9H13NO2
(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone chemical structure, C8H14N2O, CAS 1249265-80-2
(3-Aminopyrrolidin-1-yl)(cyclopropyl)methanone
CAS 1249265-80-2C8H14N2O
1-(Pyrrolidine-1-carbonyl)cyclopropane-1-carboxylic acid chemical structure, C9H13NO3, CAS 1229623-58-8
1-(Pyrrolidine-1-carbonyl)cyclopropane-1-carboxylic acid
CAS 1229623-58-8C9H13NO3
(1-Cyclopropanecarbonylpyrrolidin-3-yl)methanol chemical structure, C9H15NO2, CAS 1248053-71-5
(1-Cyclopropanecarbonylpyrrolidin-3-yl)methanol
CAS 1248053-71-5C9H15NO2
1-(Pyrrolidine-1-carbonyl)cyclopropan-1-amine chemical structure, C8H14N2O, CAS 1467755-73-2
1-(Pyrrolidine-1-carbonyl)cyclopropan-1-amine
CAS 1467755-73-2C8H14N2O
1-(Pyrrolidine-1-carbonyl)-cyclopropanecarboxylic acid methyl ester chemical structure, C10H15NO3, CAS 1174666-13-7
1-(Pyrrolidine-1-carbonyl)-cyclopropanecarboxylic acid methyl ester
CAS 1174666-13-7C10H15NO3
Cyclopropyl(3-(methylsulfonyl)pyrrolidin-1-yl)methanone chemical structure, C9H15NO3S, CAS 1448034-10-3
Cyclopropyl(3-(methylsulfonyl)pyrrolidin-1-yl)methanone
CAS 1448034-10-3C9H15NO3S
Cyclopropyl(3-(methylthio)pyrrolidin-1-yl)methanone chemical structure, C9H15NOS, CAS 1797278-33-1
Cyclopropyl(3-(methylthio)pyrrolidin-1-yl)methanone
CAS 1797278-33-1C9H15NOS