Murcko scaffold
Ring system with 2 rings and 9 atoms
51 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 51
- With full pages
- 3
Scaffold SMILES
C1COC(CC2CC2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 51 chemicals
![1-[(Oxolan-2-yl)methyl]cyclopropan-1-amine chemical structure, C8H15NO, CAS 1250985-62-6](/s/JHRKPEVURRCSEB-UHFFFAOYSA-N.svg)
1-[(Oxolan-2-yl)methyl]cyclopropan-1-amine
CAS 1250985-62-6C8H15NO
![1-[(Oxolan-2-yl)methyl]cyclopropan-1-ol chemical structure, C8H14O2, CAS 1487991-17-2](/s/IJWSGVHIDDZZJO-UHFFFAOYSA-N.svg)
1-[(Oxolan-2-yl)methyl]cyclopropan-1-ol
CAS 1487991-17-2C8H14O2
![1-{1-[(Oxolan-2-yl)methyl]cyclopropyl}methanamine chemical structure, C9H17NO, CAS 1479573-32-4](/s/YCWJGKGUHYHLFE-UHFFFAOYSA-N.svg)
1-{1-[(Oxolan-2-yl)methyl]cyclopropyl}methanamine
CAS 1479573-32-4C9H17NO
![1-[(Oxolan-2-yl)methyl]cyclopropane-1-carboxylic acid chemical structure, C9H14O3, CAS 1462956-79-1](/s/IKRIDQIJSVGPLV-UHFFFAOYSA-N.svg)
1-[(Oxolan-2-yl)methyl]cyclopropane-1-carboxylic acid
CAS 1462956-79-1C9H14O3
![{1-[(Oxolan-2-yl)methyl]cyclopropyl}methanol chemical structure, C9H16O2, CAS 1481113-58-9](/s/PJTKEZHETNCHPG-UHFFFAOYSA-N.svg)
{1-[(Oxolan-2-yl)methyl]cyclopropyl}methanol
CAS 1481113-58-9C9H16O2
![2-{[1-(Chloromethyl)cyclopropyl]methyl}oxolane chemical structure, C9H15ClO, CAS 1482882-85-8](/s/YUZQSRNMLRPLCU-UHFFFAOYSA-N.svg)
2-{[1-(Chloromethyl)cyclopropyl]methyl}oxolane
CAS 1482882-85-8C9H15ClO
![2-{[1-(Bromomethyl)cyclopropyl]methyl}oxolane chemical structure, C9H15BrO, CAS 1487126-76-0](/s/GAJVCXUQVXRADG-UHFFFAOYSA-N.svg)
2-{[1-(Bromomethyl)cyclopropyl]methyl}oxolane
CAS 1487126-76-0C9H15BrO
2-Cyclopropyl-2-(oxolan-2-yl)acetic acid
CAS 1781476-00-3C9H14O3
![n-Methyl-1-[(oxolan-2-yl)methyl]cyclopropan-1-amine chemical structure, C9H17NO, CAS 1784989-43-0](/s/OOJWIWDWEFOVHD-UHFFFAOYSA-N.svg)
n-Methyl-1-[(oxolan-2-yl)methyl]cyclopropan-1-amine
CAS 1784989-43-0C9H17NO
![2-{[1-(Chloromethyl)cyclopropyl]methyl}-5-methyloxolane chemical structure, C10H17ClO, CAS 1697862-86-4](/s/LFKVJRNOWFAVTJ-UHFFFAOYSA-N.svg)
2-{[1-(Chloromethyl)cyclopropyl]methyl}-5-methyloxolane
CAS 1697862-86-4C10H17ClO
![2-{[1-(Bromomethyl)cyclopropyl]methyl}-5-methyloxolane chemical structure, C10H17BrO, CAS 1692512-00-7](/s/UEMXSTAICLUKRP-UHFFFAOYSA-N.svg)
2-{[1-(Bromomethyl)cyclopropyl]methyl}-5-methyloxolane
CAS 1692512-00-7C10H17BrO
![{2-[Amino(cyclopropyl)methyl]oxolan-2-yl}methanol chemical structure, C9H17NO2, CAS 1820685-19-5](/s/QRVJLPJGOXCAQV-UHFFFAOYSA-N.svg)
{2-[Amino(cyclopropyl)methyl]oxolan-2-yl}methanol
CAS 1820685-19-5C9H17NO2
![1-[(Oxolan-2-yl)methyl]cyclopropane-1-carbaldehyde chemical structure, C9H14O2, CAS 1936390-21-4](/s/DNCHJPDRHWDOIF-UHFFFAOYSA-N.svg)
1-[(Oxolan-2-yl)methyl]cyclopropane-1-carbaldehyde
CAS 1936390-21-4C9H14O2
methanol chemical structure, C9H17NO2, CAS 1863466-35-6](/s/UCXDECHTYWRSEC-UHFFFAOYSA-N.svg)
[1-(Aminomethyl)cyclopropyl](oxolan-2-yl)methanol
CAS 1863466-35-6C9H17NO2
methanol chemical structure, C10H19NO2, CAS 1862530-41-3](/s/LUUMGFKRRODHEG-UHFFFAOYSA-N.svg)
[1-(Aminomethyl)cyclopropyl](5-methyloxolan-2-yl)methanol
CAS 1862530-41-3C10H19NO2
![1-[(5-Methyloxolan-2-yl)methyl]cyclopropane-1-carbaldehyde chemical structure, C10H16O2, CAS 1934967-49-3](/s/PBRNVHYDQOJLFK-UHFFFAOYSA-N.svg)
1-[(5-Methyloxolan-2-yl)methyl]cyclopropane-1-carbaldehyde
CAS 1934967-49-3C10H16O2
2-(Cyclopropylmethyl)oxolane-2-carboxylic acid
CAS 1936366-29-8C9H14O3
![1-[(5,5-Dimethyloxolan-2-yl)methyl]cyclopropane-1-carbaldehyde chemical structure, C11H18O2, CAS 1936202-77-5](/s/DCTZIDUYTVWFMF-UHFFFAOYSA-N.svg)
1-[(5,5-Dimethyloxolan-2-yl)methyl]cyclopropane-1-carbaldehyde
CAS 1936202-77-5C11H18O2
![2-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}oxolane chemical structure, C10H17BrO, CAS 2137750-64-0](/s/QUTYJLPHRQXRFG-UHFFFAOYSA-N.svg)
2-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}oxolane
CAS 2137750-64-0C10H17BrO
![(2S)-2-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}oxolane chemical structure, C10H17BrO, CAS 2137280-21-6](/s/QUTYJLPHRQXRFG-KYHHOPLUSA-N.svg)
(2S)-2-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}oxolane
CAS 2137280-21-6C10H17BrO
![(2R)-2-{[1-(Chloromethyl)cyclopropyl]methyl}oxolane chemical structure, C9H15ClO, CAS 2137037-35-3](/s/YUZQSRNMLRPLCU-MRVPVSSYSA-N.svg)
(2R)-2-{[1-(Chloromethyl)cyclopropyl]methyl}oxolane
CAS 2137037-35-3C9H15ClO
![2-{[1-(Chloromethyl)-2-methylcyclopropyl]methyl}oxolane chemical structure, C10H17ClO, CAS 2138276-39-6](/s/GTJWVGXISSLIPW-UHFFFAOYSA-N.svg)
2-{[1-(Chloromethyl)-2-methylcyclopropyl]methyl}oxolane
CAS 2138276-39-6C10H17ClO
![(2S)-2-{[1-(Bromomethyl)cyclopropyl]methyl}oxolane chemical structure, C9H15BrO, CAS 2137025-81-9](/s/GAJVCXUQVXRADG-QMMMGPOBSA-N.svg)
(2S)-2-{[1-(Bromomethyl)cyclopropyl]methyl}oxolane
CAS 2137025-81-9C9H15BrO
![1-[(Oxolan-2-yl)methyl]cyclopropane-1-sulfonyl chloride chemical structure, C8H13ClO3S, CAS 2022479-86-1](/s/PFKFIHGOWAUJNH-UHFFFAOYSA-N.svg)
1-[(Oxolan-2-yl)methyl]cyclopropane-1-sulfonyl chloride
CAS 2022479-86-1C8H13ClO3S
- 1-[(4,4-Difluorooxolan-2-yl)methyl]cyclopropane-1-sulfonyl chloride2138104-17-1C8H11ClF2O3S
- 1-{[(2S)-Oxolan-2-yl]methyl}cyclopropane-1-sulfonyl chloride2135919-75-2C8H13ClO3S
- 1-{[(2R)-Oxolan-2-yl]methyl}cyclopropane-1-sulfonyl chloride2135919-84-3C8H13ClO3S
- 1-[(4,4-Dimethyloxolan-2-yl)methyl]cyclopropane-1-sulfonyl chloride2138564-65-3C10H17ClO3S
- rac-2-{[(1R,2S)-2-ethylcyclopropyl]methyl}oxolane-2-carbaldehyde2227987-94-0C11H18O2
- 1-{[(2S)-Oxolan-2-yl]methyl}cyclopropane-1-carbaldehyde2171246-93-6C9H14O2
- 1-{[(2R)-Oxolan-2-yl]methyl}cyclopropane-1-carbaldehyde2171245-69-3C9H14O2
- 1-[(4,4-Difluorooxolan-2-yl)methyl]cyclopropane-1-carbaldehyde2172472-71-6C9H12F2O2
- 2-[(2-Ethylcyclopropyl)methyl]oxolane-2-carbaldehyde2172171-66-1C11H18O2
- 2-[(2,2-Dimethylcyclopropyl)methyl]oxolane-2-carbaldehyde2172238-59-2C11H18O2
- 2-[(2,2-Difluorocyclopropyl)methyl]oxolane-2-carbaldehyde2172025-31-7C9H12F2O2
- 2,2-Dimethyl-1-{[(2R)-oxolan-2-yl]methyl}cyclopropane-1-carbaldehyde2136509-95-8C11H18O2
- 2-[(2-Methylcyclopropyl)methyl]oxolane-2-carbaldehyde2171846-68-5C10H16O2
- tert-Butyl N-{cyclopropyl[2-(hydroxymethyl)oxolan-2-yl]methyl}carbamate2408975-80-2C14H25NO4
- 1-[2-(Oxolan-2-yl)propan-2-yl]cyclopropan-1-amine2228154-79-6C10H19NO
- N-Methyl-1-{[(5R)-5-methyloxolan-2-yl]methyl}cyclopropan-1-amine2228000-97-1C10H19NO
- 2-(Cyclopropylmethyl)oxolane-2-carbaldehyde2172588-54-2C9H14O2
- 2,2-Dimethyl-1-{[(2S)-oxolan-2-yl]methyl}cyclopropane-1-carbaldehyde2155199-46-3C11H18O2
- 2,2-Dimethyl-1-[(oxolan-2-yl)methyl]cyclopropane-1-carbaldehyde2172062-39-2C11H18O2
- 1-[(4,4-Dimethyloxolan-2-yl)methyl]cyclopropane-1-carbaldehyde2139753-97-0C11H18O2
- (2R)-2-{[1-(Chloromethyl)-2-methylcyclopropyl]methyl}oxolane2137418-50-7C10H17ClO
- (2R)-2-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}oxolane2137418-40-5C10H17BrO
- 1-[(5,5-Dimethyloxolan-2-yl)methyl]cyclopropane-1-sulfonyl chloride2025710-01-2C10H17ClO3S
- (2R)-2-{[1-(Bromomethyl)cyclopropyl]methyl}oxolane2137136-28-6C9H15BrO
Related scaffolds
Same ring framework with different atoms or bond orders
c1cnn(CC2CC2)c120 chemicals
C1CCN(CC2CC2)C18 chemicals
c1csc(NC2CC2)n17 chemicals
c1csc(CC2CC2)n16 chemicals
c1csc(CC2CC2)c15 chemicals
c1cn(CC2CC2)nn14 chemicals![Scaffold c1c[nH]c(CC2CC2)n1](/scaffold/ZNJQCGSNBJYOOX-UHFFFAOYSA-N/structure.svg)
c1c[nH]c(CC2CC2)n14 chemicals
c1cc(CC2CC2)no13 chemicals
C1CCC(CC2CC2)C13 chemicals
C1CCC(CC2CO2)C13 chemicals
O=C1CCCN1CC1CC13 chemicals
O=C(C1CC1)N1CCCC12 chemicals