Murcko scaffold
Ring system with 2 rings and 9 atoms
151 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 151
- With full pages
- 6
Scaffold SMILES
c1csc(CC2CC2)n1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 151 chemicals
Cyclopropyl(1,3-thiazol-2-yl)methanol
CAS 1211507-79-7C7H9NOS
![1-[(1,3-Thiazol-2-yl)methyl]cyclopropan-1-ol chemical structure, C7H9NOS, CAS 174183-99-4](/s/YKRGQIQPFJUPLP-UHFFFAOYSA-N.svg)
1-[(1,3-Thiazol-2-yl)methyl]cyclopropan-1-ol
CAS 174183-99-4C7H9NOS
Cyclopropyl(dimethyl-1,3-thiazol-2-yl)methanol
CAS 1211504-42-5C9H13NOS
Cyclopropyl(1,3-thiazol-2-yl)methanamine
CAS 1211514-70-3C7H10N2S
Cyclopropyl(4-methyl-1,3-thiazol-2-yl)methanol
CAS 1047663-31-9C8H11NOS
Cyclopropyl(4-methyl-1,3-thiazol-2-yl)methanamine
CAS 1211511-32-8C8H12N2S
Cyclopropyl(5-methyl-1,3-thiazol-2-yl)methanamine
CAS 1211508-04-1C8H12N2S
2-(Cyclopropylmethyl)-4-methyl-1,3-thiazole-5-carboxylic acid
CAS 1529418-76-5C9H11NO2S
Ethyl 2-(cyclopropylmethyl)-4-methyl-1,3-thiazole-5-carboxylate
CAS 1803599-92-9C11H15NO2S
![1-[(1,3-Thiazol-2-yl)methyl]cyclopropane-1-carboxylic acid chemical structure, C8H9NO2S, CAS 1529313-62-9](/s/AVUHTNYAZOPEOK-UHFFFAOYSA-N.svg)
1-[(1,3-Thiazol-2-yl)methyl]cyclopropane-1-carboxylic acid
CAS 1529313-62-9C8H9NO2S
![2-{[1-(Chloromethyl)cyclopropyl]methyl}-4-methyl-1,3-thiazole chemical structure, C9H12ClNS, CAS 1499031-86-5](/s/WPFMMBANVBTJEW-UHFFFAOYSA-N.svg)
2-{[1-(Chloromethyl)cyclopropyl]methyl}-4-methyl-1,3-thiazole
CAS 1499031-86-5C9H12ClNS
![2-{[1-(Chloromethyl)cyclopropyl]methyl}-1,3-thiazole chemical structure, C8H10ClNS, CAS 1503153-40-9](/s/OQLLMEKWCPOBEP-UHFFFAOYSA-N.svg)
2-{[1-(Chloromethyl)cyclopropyl]methyl}-1,3-thiazole
CAS 1503153-40-9C8H10ClNS
![2-{[1-(Bromomethyl)cyclopropyl]methyl}-4-methyl-1,3-thiazole chemical structure, C9H12BrNS, CAS 1509368-00-6](/s/ONLRLJGJHDPRRF-UHFFFAOYSA-N.svg)
2-{[1-(Bromomethyl)cyclopropyl]methyl}-4-methyl-1,3-thiazole
CAS 1509368-00-6C9H12BrNS
![2-{[1-(Bromomethyl)cyclopropyl]methyl}-1,3-thiazole chemical structure, C8H10BrNS, CAS 1511798-42-7](/s/WCLWHUDIXSUZMI-UHFFFAOYSA-N.svg)
2-{[1-(Bromomethyl)cyclopropyl]methyl}-1,3-thiazole
CAS 1511798-42-7C8H10BrNS
![{1-[(1,3-Thiazol-2-yl)methyl]cyclopropyl}methanol chemical structure, C8H11NOS, CAS 1508775-27-6](/s/CXZVUWIMFVODAH-UHFFFAOYSA-N.svg)
{1-[(1,3-Thiazol-2-yl)methyl]cyclopropyl}methanol
CAS 1508775-27-6C8H11NOS
![1-[(1,3-Thiazol-2-yl)methyl]cyclopropan-1-amine chemical structure, C7H10N2S, CAS 1525480-87-8](/s/LJYVQTUVOBKINC-UHFFFAOYSA-N.svg)
1-[(1,3-Thiazol-2-yl)methyl]cyclopropan-1-amine
CAS 1525480-87-8C7H10N2S
![1-{1-[(1,3-Thiazol-2-yl)methyl]cyclopropyl}methanamine chemical structure, C8H12N2S, CAS 1522330-00-2](/s/OLJHCSDVTJNGOM-UHFFFAOYSA-N.svg)
1-{1-[(1,3-Thiazol-2-yl)methyl]cyclopropyl}methanamine
CAS 1522330-00-2C8H12N2S
2-Thiazolemethanamine, I+/--cyclopropyl-I+/--(methoxymethyl)-
CAS 1520510-35-3C9H14N2OS
2-(Cyclopropylmethyl)-1,3-thiazole-5-carboxylic acid
CAS 1526717-05-4C8H9NO2S
2-Cyclopropyl-2-(2-thiazolyl)acetic Acid
CAS 1780191-89-0C8H9NO2S
![N-[Cyclopropyl(5-methyl-1,3-thiazol-2-yl)methyl]prop-2-enamide chemical structure, C11H14N2OS, CAS 2094309-95-0](/s/UXCOXYSUYYKMEQ-UHFFFAOYSA-N.svg)
N-[Cyclopropyl(5-methyl-1,3-thiazol-2-yl)methyl]prop-2-enamide
CAS 2094309-95-0C11H14N2OS
methanol chemical structure, C8H12N2OS, CAS 1855393-81-5](/s/XEJKCUKLHANIEE-UHFFFAOYSA-N.svg)
[1-(Aminomethyl)cyclopropyl](1,3-thiazol-2-yl)methanol
CAS 1855393-81-5C8H12N2OS
methanol chemical structure, C9H14N2OS, CAS 1876483-34-9](/s/MLLOLPQNMKQHEX-UHFFFAOYSA-N.svg)
[1-(Aminomethyl)cyclopropyl](4-methyl-1,3-thiazol-2-yl)methanol
CAS 1876483-34-9C9H14N2OS
methanol chemical structure, C8H11ClN2OS, CAS 1863665-23-9](/s/LGUGWMLBKQBVLZ-UHFFFAOYSA-N.svg)
[1-(Aminomethyl)cyclopropyl](5-chloro-1,3-thiazol-2-yl)methanol
CAS 1863665-23-9C8H11ClN2OS
- [1-(Aminomethyl)cyclopropyl](5-iodo-1,3-thiazol-2-yl)methanol1864642-65-8C8H11IN2OS
- 1-[(4,5-Dimethyl-1,3-thiazol-2-yl)methyl]cyclopropane-1-carbaldehyde1934703-72-6C10H13NOS
- 1-[(1,3-Thiazol-2-yl)methyl]cyclopropane-1-carbaldehyde1935125-58-8C8H9NOS
- 1-[(4-Methyl-1,3-thiazol-2-yl)methyl]cyclopropane-1-carbaldehyde1936390-26-9C9H11NOS
- [1-(Aminomethyl)cyclopropyl](5-methyl-1,3-thiazol-2-yl)methanol1857342-61-0C9H14N2OS
- N-[Cyclopropyl(1,3-thiazol-2-yl)methyl]prop-2-enamide2175581-25-4C10H12N2OS
- N-(1-Cyano-2-methoxy-1-methylethyl)-2-(cyclopropylmethyl)-4-methyl-1,3-thiazole-5-carboxamide2224386-69-8C14H19N3O2S
- N-({[Cyclopropyl(5-methyl-1,3-thiazol-2-yl)methyl]carbamoyl}methyl)-N-methylprop-2-enamide2198302-37-1C14H19N3O2S
- 2-Chloro-N-[cyclopropyl(4-methyl-1,3-thiazol-2-yl)methyl]acetamide2411300-25-7C10H13ClN2OS
- N-[Cyclopropyl(4-methyl-1,3-thiazol-2-yl)methyl]prop-2-enamide2411196-31-9C11H14N2OS
- (E)-N-[Cyclopropyl-(4-methyl-1,3-thiazol-2-yl)methyl]-4-(dimethylamino)but-2-enamide2411333-36-1C14H21N3OS
- 2-Chloro-N-[cyclopropyl(5-methyl-1,3-thiazol-2-yl)methyl]propanamide2411220-36-3C11H15ClN2OS
- 1-Cyclopropyl-1-(1,3-thiazol-2-yl)methanamine hydrochloride2708277-99-8C7H11ClN2S
- 5-Bromo-2-{[1-(chloromethyl)cyclopropyl]methyl}-1,3-thiazole2138164-70-0C8H9BrClNS
- 2-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}-1,3-thiazole2137727-09-2C9H12BrNS
- 2-[Bromo(1-methylcyclopropyl)methyl]-1,3-thiazole-5-carbaldehyde2167725-49-5C9H10BrNOS
- [1-(Aminomethyl)cyclopropyl](5-bromo-1,3-thiazol-2-yl)methanol2137841-19-9C8H11BrN2OS
- Methyl 2-[bromo(2-methylcyclopropyl)methyl]-1,3-thiazole-5-carboxylate2167206-87-1C10H12BrNO2S
- Methyl 2-[bromo(cyclopropyl)methyl]-4-methyl-1,3-thiazole-5-carboxylate2168620-67-3C10H12BrNO2S
- (4-Methyl-1,3-thiazol-2-yl)(1-methylcyclopropyl)methanol2171870-21-4C9H13NOS
- {4-[(Methylamino)methyl]-1,3-thiazol-2-yl}(1-methylcyclopropyl)methanol2169513-06-6C10H16N2OS
- {4-Methyl-5-[(methylamino)methyl]-1,3-thiazol-2-yl}(1-methylcyclopropyl)methanol2168936-37-4C11H18N2OS
- [5-(Aminomethyl)-4-methyl-1,3-thiazol-2-yl](2-methylcyclopropyl)methanol2168295-34-7C10H16N2OS
- 2-[Hydroxy(1-methylcyclopropyl)methyl]-4-methyl-1,3-thiazole-5-carbaldehyde2166897-22-7C10H13NO2S
Related scaffolds
Same ring framework with different atoms or bond orders
c1cnn(CC2CC2)c120 chemicals
C1CCN(CC2CC2)C18 chemicals
c1csc(NC2CC2)n17 chemicals
c1csc(CC2CC2)c15 chemicals
c1cn(CC2CC2)nn14 chemicals![Scaffold c1c[nH]c(CC2CC2)n1](/scaffold/ZNJQCGSNBJYOOX-UHFFFAOYSA-N/structure.svg)
c1c[nH]c(CC2CC2)n14 chemicals
c1cc(CC2CC2)no13 chemicals
C1CCC(CC2CC2)C13 chemicals
C1COC(CC2CC2)C13 chemicals
C1CCC(CC2CO2)C13 chemicals
O=C1CCCN1CC1CC13 chemicals
O=C(C1CC1)N1CCCC12 chemicals