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Murcko scaffold

N-Phenyl-4-isoxazolecarboxamide scaffold

160 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
160
With full pages
28
Scaffold SMILES

O=C(Nc1ccccc1)c1cnoc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-4-isoxazolecarboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1cnoc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 160 chemicals

Leflunomide chemical structure, C12H9F3N2O2, CAS 75706-12-6
Leflunomide
CAS 75706-12-6C12H9F3N2O2
3-Carboxy-5-methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide chemical structure, C13H9F3N2O4, CAS 134888-93-0
3-Carboxy-5-methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
CAS 134888-93-0C13H9F3N2O4
4-Isoxazolecarboxamide, 3-carboxy-5-methyl-N-(4-(trifluoromethoxy)phenyl)- chemical structure, C13H9F3N2O5, CAS 134889-32-0
4-Isoxazolecarboxamide, 3-carboxy-5-methyl-N-(4-(trifluoromethoxy)phenyl)-
CAS 134889-32-0C13H9F3N2O5
5-Amino-N-(3-chloro-4-fluorophenyl)-3-methylisoxazole-4-carboxamide chemical structure, C11H9ClFN3O2, CAS 695191-77-6
5-Amino-N-(3-chloro-4-fluorophenyl)-3-methylisoxazole-4-carboxamide
CAS 695191-77-6C11H9ClFN3O2
4-Isoxazolecarboxamide, 5-amino-N-[4-(chlorodifluoromethoxy)phenyl]-3-methyl- chemical structure, C12H10ClF2N3O3, CAS 524036-07-5
4-Isoxazolecarboxamide, 5-amino-N-[4-(chlorodifluoromethoxy)phenyl]-3-methyl-
CAS 524036-07-5C12H10ClF2N3O3
5-Amino-3-methyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxamide chemical structure, C12H10F3N3O3, CAS 524036-08-6
5-Amino-3-methyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxamide
CAS 524036-08-6C12H10F3N3O3
3,5-Dimethyl-N-phenyl-1,2-oxazole-4-carboxamide chemical structure, C12H12N2O2, CAS 260047-11-8
3,5-Dimethyl-N-phenyl-1,2-oxazole-4-carboxamide
CAS 260047-11-8C12H12N2O2
N-(4-Methoxyphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C13H14N2O3, CAS 260047-12-9
N-(4-Methoxyphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 260047-12-9C13H14N2O3
N-(4-Chlorophenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C12H11ClN2O2, CAS 260047-13-0
N-(4-Chlorophenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 260047-13-0C12H11ClN2O2
5-Amino-3-ethyl-N-(4-fluorophenyl)-1,2-oxazole-4-carboxamide chemical structure, C12H12FN3O2, CAS 632291-87-3
5-Amino-3-ethyl-N-(4-fluorophenyl)-1,2-oxazole-4-carboxamide
CAS 632291-87-3C12H12FN3O2
5-Amino-N-(3-chloro-4-methylphenyl)-3-ethyl-1,2-oxazole-4-carboxamide chemical structure, C13H14ClN3O2, CAS 632291-86-2
5-Amino-N-(3-chloro-4-methylphenyl)-3-ethyl-1,2-oxazole-4-carboxamide
CAS 632291-86-2C13H14ClN3O2
5-Amino-N-(3-chloro-4-fluorophenyl)-3-ethylisoxazole-4-carboxamide chemical structure, C12H11ClFN3O2, CAS 632291-66-8
5-Amino-N-(3-chloro-4-fluorophenyl)-3-ethylisoxazole-4-carboxamide
CAS 632291-66-8C12H11ClFN3O2
N-(3-Chloro-2-methylphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C13H13ClN2O2, CAS 289630-15-5
N-(3-Chloro-2-methylphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 289630-15-5C13H13ClN2O2
N-(4-Bromophenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C12H11BrN2O2, CAS 289630-22-4
N-(4-Bromophenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 289630-22-4C12H11BrN2O2
N-(2,4-Dimethylphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C14H16N2O2, CAS 289630-28-0
N-(2,4-Dimethylphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 289630-28-0C14H16N2O2
N-(3,4-Dimethylphenyl)-3,5-dimethyl-4-isoxazolecarboxamide chemical structure, C14H16N2O2, CAS 289630-30-4
N-(3,4-Dimethylphenyl)-3,5-dimethyl-4-isoxazolecarboxamide
CAS 289630-30-4C14H16N2O2
3,5-Dimethyl-N-(4-methylphenyl)-4-isoxazolecarboxamide chemical structure, C13H14N2O2, CAS 289630-31-5
3,5-Dimethyl-N-(4-methylphenyl)-4-isoxazolecarboxamide
CAS 289630-31-5C13H14N2O2
N-(2-Methoxyphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide chemical structure, C13H14N2O3, CAS 289630-34-8
N-(2-Methoxyphenyl)-3,5-dimethyl-1,2-oxazole-4-carboxamide
CAS 289630-34-8C13H14N2O3
4-Isoxazolecarboxamide, 5-methyl-N-phenyl- chemical structure, C11H10N2O2, CAS 134319-17-8
4-Isoxazolecarboxamide, 5-methyl-N-phenyl-
CAS 134319-17-8C11H10N2O2
5-Methyl-N-(4-methylphenyl)isoxazole-4-carboxamide chemical structure, C12H12N2O2, CAS 724429-16-7
5-Methyl-N-(4-methylphenyl)isoxazole-4-carboxamide
CAS 724429-16-7C12H12N2O2
N-(2-Methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C12H12N2O3, CAS 61643-29-6
N-(2-Methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 61643-29-6C12H12N2O3
N-(3-Methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C12H12N2O3, CAS 61643-30-9
N-(3-Methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 61643-30-9C12H12N2O3
Methyl 3-(5-methylisoxazole-4-carboxamido)benzoate chemical structure, C13H12N2O4, CAS 724430-95-9
Methyl 3-(5-methylisoxazole-4-carboxamido)benzoate
CAS 724430-95-9C13H12N2O4
N-(4-Chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C11H9ClN2O2, CAS 61643-17-2
N-(4-Chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
CAS 61643-17-2C11H9ClN2O2