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Murcko scaffold

2-Pyrrolidinone, 3-phenyl- scaffold

52 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
52
With full pages
4
Scaffold SMILES

O=C1NCCC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Pyrrolidinone, 3-phenyl- page
Murcko scaffold O=C1NCCC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

1-Methyl-3-phenylpyrrolidin-2-one chemical structure, C11H13NO, CAS 54520-82-0
1-Methyl-3-phenylpyrrolidin-2-one
CAS 54520-82-0C11H13NO
3-(4-Methoxyphenyl)-1-methyl-2-pyrrolidinone chemical structure, C12H15NO2, CAS 107770-12-7
3-(4-Methoxyphenyl)-1-methyl-2-pyrrolidinone
CAS 107770-12-7C12H15NO2
2-Pyrrolidinone, 3-phenyl- chemical structure, C10H11NO, CAS 6836-97-1
2-Pyrrolidinone, 3-phenyl-
CAS 6836-97-1C10H11NO
2-Pyrrolidinecarboxylic acid, 5-oxo-3-pentyl-4-phenyl- chemical structure, C16H21NO3, CAS 69727-32-8
2-Pyrrolidinecarboxylic acid, 5-oxo-3-pentyl-4-phenyl-
CAS 69727-32-8C16H21NO3
3-[2-(Dimethylamino)ethyl]-1-methyl-3-phenylpyrrolidin-2-one chemical structure, C15H22N2O, CAS 20538-18-5
3-[2-(Dimethylamino)ethyl]-1-methyl-3-phenylpyrrolidin-2-one
CAS 20538-18-5C15H22N2O
1-Amino-3-(4-chlorophenyl)pyrrolidin-2-one chemical structure, C10H11ClN2O, CAS 63885-94-9
1-Amino-3-(4-chlorophenyl)pyrrolidin-2-one
CAS 63885-94-9C10H11ClN2O
2-Pyrrolidinone, 3-ethyl-3-phenyl- chemical structure, C12H15NO, CAS 77236-50-1
2-Pyrrolidinone, 3-ethyl-3-phenyl-
CAS 77236-50-1C12H15NO
2-Oxo-3-phenylpyrrolidine-3-carboxylic acid chemical structure, C11H11NO3, CAS 167398-74-5
2-Oxo-3-phenylpyrrolidine-3-carboxylic acid
CAS 167398-74-5C11H11NO3
(R)-3-Phenylpyrrolidin-2-one chemical structure, C10H11NO, CAS 221247-82-1
(R)-3-Phenylpyrrolidin-2-one
CAS 221247-82-1C10H11NO
(S)-3-Phenylpyrrolidin-2-one chemical structure, C10H11NO, CAS 221247-75-2
(S)-3-Phenylpyrrolidin-2-one
CAS 221247-75-2C10H11NO
1,3-Dimethyl-3-phenylpyrrolidin-2-one chemical structure, C12H15NO, CAS 64097-67-2
1,3-Dimethyl-3-phenylpyrrolidin-2-one
CAS 64097-67-2C12H15NO
3-(3-(Trifluoromethyl)phenyl)pyrrolidin-2-one chemical structure, C11H10F3NO, CAS 94559-28-1
3-(3-(Trifluoromethyl)phenyl)pyrrolidin-2-one
CAS 94559-28-1C11H10F3NO
5-(Hydroxymethyl)-3-phenylpyrrolidin-2-one chemical structure, C11H13NO2, CAS 133390-84-8
5-(Hydroxymethyl)-3-phenylpyrrolidin-2-one
CAS 133390-84-8C11H13NO2
3-(2-Diethylaminoethyl)-1-ethyl-3-phenylpyrrolidin-2-one hydrochloride chemical structure, C18H29ClN2O, CAS 7512-13-2
3-(2-Diethylaminoethyl)-1-ethyl-3-phenylpyrrolidin-2-one hydrochloride
CAS 7512-13-2C18H29ClN2O
3-(3,4-Dimethoxyphenyl)-1-methylpyrrolidin-2-one chemical structure, C13H17NO3, CAS 88741-39-3
3-(3,4-Dimethoxyphenyl)-1-methylpyrrolidin-2-one
CAS 88741-39-3C13H17NO3
Neoselaginellic acid chemical structure, C18H24N2O3, CAS 1158820-19-9
Neoselaginellic acid
CAS 1158820-19-9C18H24N2O3
2-(2-Oxo-3-phenylpyrrolidin-1-yl)acetamide chemical structure, C12H14N2O2, CAS 88981-88-8
2-(2-Oxo-3-phenylpyrrolidin-1-yl)acetamide
CAS 88981-88-8C12H14N2O2
3-(4-Chlorophenyl)pyrrolidin-2-one chemical structure, C10H10ClNO, CAS 120418-69-1
3-(4-Chlorophenyl)pyrrolidin-2-one
CAS 120418-69-1C10H10ClNO
3-(3-Bromophenyl)pyrrolidin-2-one chemical structure, C10H10BrNO, CAS 1004294-74-9
3-(3-Bromophenyl)pyrrolidin-2-one
CAS 1004294-74-9C10H10BrNO
3-(4-Fluorophenyl)pyrrolidin-2-one chemical structure, C10H10FNO, CAS 1219626-26-2
3-(4-Fluorophenyl)pyrrolidin-2-one
CAS 1219626-26-2C10H10FNO
1-Pyrrolidineacetic acid, 2-oxo-3-phenyl-, ethyl ester chemical structure, C14H17NO3, CAS 88981-96-8
1-Pyrrolidineacetic acid, 2-oxo-3-phenyl-, ethyl ester
CAS 88981-96-8C14H17NO3
3-(2-Acetamidophenyl)-1-methyl-2-oxopyrrolidin-3-yl acetate chemical structure, C15H18N2O4, CAS 62209-21-6
3-(2-Acetamidophenyl)-1-methyl-2-oxopyrrolidin-3-yl acetate
CAS 62209-21-6C15H18N2O4
N-(2-(3-Hydroxy-1-methyl-2-oxopyrrolidin-3-yl)phenyl)acetamide chemical structure, C13H16N2O3, CAS 62209-20-5
N-(2-(3-Hydroxy-1-methyl-2-oxopyrrolidin-3-yl)phenyl)acetamide
CAS 62209-20-5C13H16N2O3
3-(3,4-Dimethoxyphenyl)pyrrolidin-2-one chemical structure, C12H15NO3, CAS 52413-27-1
3-(3,4-Dimethoxyphenyl)pyrrolidin-2-one
CAS 52413-27-1C12H15NO3