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Murcko scaffold

5,6,7,8-Tetrahydroisoquinolin-1(2H)-one scaffold

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
14
With full pages
0
Scaffold SMILES

O=c1[nH]ccc2c1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydroisoquinolin-1(2H)-one page
Murcko scaffold O=c1[nH]ccc2c1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Ctk1E2106 chemical structure, C12H14N2O2, CAS 56154-47-3
Ctk1E2106
CAS 56154-47-3C12H14N2O2
3,4-Dimethyl-5,6,7,8-tetrahydroisoquinolin-1(2H)-one chemical structure, C11H15NO, CAS 62614-93-1
3,4-Dimethyl-5,6,7,8-tetrahydroisoquinolin-1(2H)-one
CAS 62614-93-1C11H15NO
3-Amino-1-oxo-1,2,5,6,7,8-hexahydroisoquinoline-4-carboxamide chemical structure, C10H13N3O2, CAS 102873-02-9
3-Amino-1-oxo-1,2,5,6,7,8-hexahydroisoquinoline-4-carboxamide
CAS 102873-02-9C10H13N3O2
5,6,7,8-Tetrahydroisoquinolin-1(2H)-one chemical structure, C9H11NO, CAS 26345-15-3
5,6,7,8-Tetrahydroisoquinolin-1(2H)-one
CAS 26345-15-3C9H11NO
1(2H)-Isoquinolinone,5-ethyl-5,6,7,8-tetrahydro-5,6,7-trihydroxy- chemical structure, C11H15NO4, CAS 340268-67-9
1(2H)-Isoquinolinone,5-ethyl-5,6,7,8-tetrahydro-5,6,7-trihydroxy-
CAS 340268-67-9C11H15NO4
4-Bromo-3-methyl-5,6,7,8-tetrahydro-2H-isoquinolin-1-one chemical structure, C10H12BrNO, CAS 861136-82-5
4-Bromo-3-methyl-5,6,7,8-tetrahydro-2H-isoquinolin-1-one
CAS 861136-82-5C10H12BrNO
4-Bromo-1,2,5,6,7,8-hexahydroisoquinolin-1-one chemical structure, C9H10BrNO, CAS 860368-23-6
4-Bromo-1,2,5,6,7,8-hexahydroisoquinolin-1-one
CAS 860368-23-6C9H10BrNO
1-Oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile chemical structure, C10H10N2O, CAS 1357185-53-5
1-Oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
CAS 1357185-53-5C10H10N2O
1-Hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carboxylic acid chemical structure, C10H11NO3, CAS 1520396-20-6
1-Hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carboxylic acid
CAS 1520396-20-6C10H11NO3
2-Methyl-1-oxo-1,2,5,6,7,8-hexahydroisoquinoline-4-carboxylic acid chemical structure, C11H13NO3, CAS 1798775-82-2
2-Methyl-1-oxo-1,2,5,6,7,8-hexahydroisoquinoline-4-carboxylic acid
CAS 1798775-82-2C11H13NO3
4-Bromo-2-methyl-5,6,7,8-tetrahydroisoquinolin-1-one chemical structure, C10H12BrNO, CAS 1706750-72-2
4-Bromo-2-methyl-5,6,7,8-tetrahydroisoquinolin-1-one
CAS 1706750-72-2C10H12BrNO
4-Chloro-5,6,7,8-tetrahydroisoquinolin-1(2H)-one chemical structure, C9H10ClNO, CAS 2383997-71-3
4-Chloro-5,6,7,8-tetrahydroisoquinolin-1(2H)-one
CAS 2383997-71-3C9H10ClNO
Methyl 1-hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carboxylate chemical structure, C11H13NO3, CAS 2092431-08-6
Methyl 1-hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carboxylate
CAS 2092431-08-6C11H13NO3
3-Chloro-5,6,7,8-tetrahydro-1(2H)-isoquinolinone chemical structure, C9H10ClNO, CAS 25297-50-1
3-Chloro-5,6,7,8-tetrahydro-1(2H)-isoquinolinone
CAS 25297-50-1C9H10ClNO