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Murcko scaffold

Ring system with 3 rings and 15 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
8
With full pages
2
Scaffold SMILES

C1=CC2(CCCCC2)Cc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC2(CCCCC2)Cc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1-Aminospiro[4H-naphthalene-3,1'-cyclohexane]-2-carbonitrile chemical structure, C16H18N2, CAS 5243-14-1
1-Aminospiro[4H-naphthalene-3,1'-cyclohexane]-2-carbonitrile
CAS 5243-14-1C16H18N2
2-Chloro-N-(3'-cyano-1'H-spiro[cyclohexane-1,2'-naphthalen]-4'-yl)acetamide chemical structure, C18H19ClN2O, CAS 135586-99-1
2-Chloro-N-(3'-cyano-1'H-spiro[cyclohexane-1,2'-naphthalen]-4'-yl)acetamide
CAS 135586-99-1C18H19ClN2O
Ethyl 1-(propanoylamino)spiro[4H-naphthalene-3,1'-cyclohexane]-2-carboxylate chemical structure, C21H27NO3, CAS 300705-48-0
Ethyl 1-(propanoylamino)spiro[4H-naphthalene-3,1'-cyclohexane]-2-carboxylate
CAS 300705-48-0C21H27NO3
Ethyl 1-aminospiro[4H-naphthalene-3,1'-cyclohexane]-2-carboxylate chemical structure, C18H23NO2, CAS 127025-64-3
Ethyl 1-aminospiro[4H-naphthalene-3,1'-cyclohexane]-2-carboxylate
CAS 127025-64-3C18H23NO2
N-(2-Cyanospiro[4H-naphthalene-3,1'-cyclohexane]-1-yl)propanamide chemical structure, C19H22N2O, CAS 135587-00-7
N-(2-Cyanospiro[4H-naphthalene-3,1'-cyclohexane]-1-yl)propanamide
CAS 135587-00-7C19H22N2O
Ethyl 4'-(N-acetylacetamido)-1'H-spiro[cyclohexane-1,2'-naphthalene]-3'-carboxylate chemical structure, C22H27NO4, CAS 331837-21-9
Ethyl 4'-(N-acetylacetamido)-1'H-spiro[cyclohexane-1,2'-naphthalene]-3'-carboxylate
CAS 331837-21-9C22H27NO4
Ethyl 1-(pentanoylamino)spiro[4H-naphthalene-3,1'-cyclohexane]-2-carboxylate chemical structure, C23H31NO3, CAS 380565-37-7
Ethyl 1-(pentanoylamino)spiro[4H-naphthalene-3,1'-cyclohexane]-2-carboxylate
CAS 380565-37-7C23H31NO3
4-Propionylamino-3-cyano-1,2-dihydrospiro(naphthalene-2,1'-cyclohexane) chemical structure, C19H22N2O, CAS 135586-95-7
4-Propionylamino-3-cyano-1,2-dihydrospiro(naphthalene-2,1'-cyclohexane)
CAS 135586-95-7C19H22N2O