Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Spiro[2H-1,3-benzoxazine-2,4'-piperidin]-4(3H)-one scaffold

26 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 26
With full pages: 2

Scaffold SMILES

O=C1NC2(CCNCC2)Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Spiro[2H-1,3-benzoxazine-2,4'-piperidin]-4(3H)-one page

Murcko scaffold O=C1NC2(CCNCC2)Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

Spiro[2H-1,3-benzoxazine-2,4'-piperidin]-4(3H)-one chemical structure, C12H14N2O2, CAS 54906-24-0

Spiro[2H-1,3-benzoxazine-2,4'-piperidin]-4(3H)-one

CAS 54906-24-0C₁₂H₁₄N₂O₂

1'-Methylspiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one chemical structure, C13H16N2O2, CAS 77773-95-6

1'-Methylspiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one

CAS 77773-95-6C₁₃H₁₆N₂O₂

1'-Ethylspiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one chemical structure, C14H18N2O2, CAS 883047-33-4

1'-Ethylspiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one

CAS 883047-33-4C₁₄H₁₈N₂O₂

tert-Butyl 6-bromo-4-oxo-3,4-dihydro-1'H-spiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxylate chemical structure, C17H21BrN2O4, CAS 690632-05-4

tert-Butyl 6-bromo-4-oxo-3,4-dihydro-1'H-spiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxylate

CAS 690632-05-4C₁₇H₂₁BrN₂O₄

6-Bromospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one 2,2,2-trifluoroacetate chemical structure, C14H14BrF3N2O4, CAS 691868-46-9

6-Bromospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one 2,2,2-trifluoroacetate

CAS 691868-46-9C₁₄H₁₄BrF₃N₂O₄

6-Bromospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one chemical structure, C12H13BrN2O2, CAS 691868-45-8

6-Bromospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one

CAS 691868-45-8C₁₂H₁₃BrN₂O₂

tert-Butyl 4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate chemical structure, C17H22N2O4, CAS 1086389-63-0

tert-Butyl 4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate

CAS 1086389-63-0C₁₇H₂₂N₂O₄

6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one chemical structure, C13H16N2O2, CAS 1204346-46-2

6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one

CAS 1204346-46-2C₁₃H₁₆N₂O₂

6-Methoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride chemical structure, C13H17ClN2O3, CAS 1204346-31-5

6-Methoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride

CAS 1204346-31-5C₁₃H₁₇ClN₂O₃

6-Methoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one chemical structure, C13H16N2O3, CAS 1204386-91-3

6-Methoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one

CAS 1204386-91-3C₁₃H₁₆N₂O₃

tert-Butyl 6-methyl-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate chemical structure, C18H24N2O4, CAS 1204345-63-0

tert-Butyl 6-methyl-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate

CAS 1204345-63-0C₁₈H₂₄N₂O₄

tert-Butyl 7-amino-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate chemical structure, C17H23N3O4, CAS 1192355-14-8

tert-Butyl 7-amino-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate

CAS 1192355-14-8C₁₇H₂₃N₃O₄

tert-Butyl 6-amino-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate chemical structure, C17H23N3O4, CAS 1260763-65-2

tert-Butyl 6-amino-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate

CAS 1260763-65-2C₁₇H₂₃N₃O₄

tert-Butyl (4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-6-yl)carbamate chemical structure, C17H23N3O4, CAS 1260897-81-1

tert-Butyl (4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-6-yl)carbamate

CAS 1260897-81-1C₁₇H₂₃N₃O₄

tert-Butyl (4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-7-yl)carbamate chemical structure, C17H23N3O4, CAS 1260883-15-5

tert-Butyl (4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-7-yl)carbamate

CAS 1260883-15-5C₁₇H₂₃N₃O₄

6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one 2,2,2-trifluoroacetate chemical structure, C15H17F3N2O4, CAS 1204346-47-3

6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one 2,2,2-trifluoroacetate

CAS 1204346-47-3C₁₅H₁₇F₃N₂O₄

5-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one chemical structure, C13H16N2O2, CAS 1241953-90-1

5-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one

CAS 1241953-90-1C₁₃H₁₆N₂O₂

Spiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one hydrochloride chemical structure, C12H15ClN2O2, CAS 54906-23-9

Spiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one hydrochloride

CAS 54906-23-9C₁₂H₁₅ClN₂O₂

6-Ethoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt chemical structure, C14H19ClN2O3, CAS 1823188-30-2

6-Ethoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt

CAS 1823188-30-2C₁₄H₁₉ClN₂O₃

6-Ethoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one chemical structure, C14H18N2O3, CAS 1823188-29-9

6-Ethoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one

CAS 1823188-29-9C₁₄H₁₈N₂O₃

6-Isopropoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt chemical structure, C15H21ClN2O3, CAS 1823184-45-7

6-Isopropoxyspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt

CAS 1823184-45-7C₁₅H₂₁ClN₂O₃

6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt chemical structure, C13H17ClN2O2, CAS 1451154-33-8

6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt

CAS 1451154-33-8C₁₃H₁₇ClN₂O₂

6-(Trifluoromethoxy)spiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt chemical structure, C13H14ClF3N2O3, CAS 1823184-48-0

6-(Trifluoromethoxy)spiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride salt

CAS 1823184-48-0C₁₃H₁₄ClF₃N₂O₃

6-(Trifluoromethoxy)spiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one chemical structure, C13H13F3N2O3, CAS 1823184-47-9

6-(Trifluoromethoxy)spiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one

CAS 1823184-47-9C₁₃H₁₃F₃N₂O₃