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Murcko scaffold

Ring system with 3 rings and 18 atoms

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
39
With full pages
10
Scaffold SMILES

c1ccc(CSc2ncc3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2ncc3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

4-Methyl-2-[(4-nitrophenyl)methylsulfanyl]quinazoline chemical structure, C16H13N3O2S, CAS 351225-35-9
4-Methyl-2-[(4-nitrophenyl)methylsulfanyl]quinazoline
CAS 351225-35-9C16H13N3O2S
4,6-Dimethyl-2-[(4-nitrobenzyl)sulfanyl]quinazoline chemical structure, C17H15N3O2S, CAS 5874-42-0
4,6-Dimethyl-2-[(4-nitrobenzyl)sulfanyl]quinazoline
CAS 5874-42-0C17H15N3O2S
6-Methoxy-4-methyl-2-[(4-nitrobenzyl)sulfanyl]quinazoline chemical structure, C17H15N3O3S, CAS 351225-39-3
6-Methoxy-4-methyl-2-[(4-nitrobenzyl)sulfanyl]quinazoline
CAS 351225-39-3C17H15N3O3S
4-Chlorobenzyl 4-methyl-2-quinazolinyl sulfide chemical structure, C16H13ClN2S, CAS 352659-18-8
4-Chlorobenzyl 4-methyl-2-quinazolinyl sulfide
CAS 352659-18-8C16H13ClN2S
2-[(4-Chlorobenzyl)thio]-4,7-dimethylquinazoline chemical structure, C17H15ClN2S, CAS 355824-33-8
2-[(4-Chlorobenzyl)thio]-4,7-dimethylquinazoline
CAS 355824-33-8C17H15ClN2S
2-[(4-Chlorophenyl)methylsulfanyl]-4,6,7-trimethylquinazoline chemical structure, C18H17ClN2S, CAS 361179-34-2
2-[(4-Chlorophenyl)methylsulfanyl]-4,6,7-trimethylquinazoline
CAS 361179-34-2C18H17ClN2S
2-[(4-Chlorobenzyl)sulfanyl]-4,6-dimethylquinazoline chemical structure, C17H15ClN2S, CAS 361992-16-7
2-[(4-Chlorobenzyl)sulfanyl]-4,6-dimethylquinazoline
CAS 361992-16-7C17H15ClN2S
2-(Benzylsulfanyl)-4,6,7-trimethylquinazoline chemical structure, C18H18N2S, CAS 371957-17-4
2-(Benzylsulfanyl)-4,6,7-trimethylquinazoline
CAS 371957-17-4C18H18N2S
2-Benzylsulfanyl-4,7-dimethylquinazoline chemical structure, C17H16N2S, CAS 330828-12-1
2-Benzylsulfanyl-4,7-dimethylquinazoline
CAS 330828-12-1C17H16N2S
2-[(4-Chlorobenzyl)sulfanyl]-6-ethoxy-4-methylquinazoline chemical structure, C18H17ClN2OS, CAS 361999-11-3
2-[(4-Chlorobenzyl)sulfanyl]-6-ethoxy-4-methylquinazoline
CAS 361999-11-3C18H17ClN2OS
6-Methoxy-4-methyl-2-[(3-nitrophenyl)methylsulfanyl]quinazoline chemical structure, C17H15N3O3S, CAS 377063-62-2
6-Methoxy-4-methyl-2-[(3-nitrophenyl)methylsulfanyl]quinazoline
CAS 377063-62-2C17H15N3O3S
4,6-Dimethyl-2-[(3-nitrophenyl)methylsulfanyl]quinazoline chemical structure, C17H15N3O2S, CAS 377050-73-2
4,6-Dimethyl-2-[(3-nitrophenyl)methylsulfanyl]quinazoline
CAS 377050-73-2C17H15N3O2S
6-Methoxy-4-methyl-2-[(2-methylphenyl)methylthio]quinazoline chemical structure, C18H18N2OS, CAS 524056-36-8
6-Methoxy-4-methyl-2-[(2-methylphenyl)methylthio]quinazoline
CAS 524056-36-8C18H18N2OS
6-Methoxy-4-methyl-2-[(3-methylphenyl)methylsulfanyl]quinazoline chemical structure, C18H18N2OS, CAS 489413-19-6
6-Methoxy-4-methyl-2-[(3-methylphenyl)methylsulfanyl]quinazoline
CAS 489413-19-6C18H18N2OS
2-(Benzylthio)-6-methoxy-4-methylquinazoline chemical structure, C17H16N2OS, CAS 500272-00-4
2-(Benzylthio)-6-methoxy-4-methylquinazoline
CAS 500272-00-4C17H16N2OS
2-[(3-Chlorophenyl)methylsulfanyl]-4,6-dimethylquinazoline chemical structure, C17H15ClN2S, CAS 498536-90-6
2-[(3-Chlorophenyl)methylsulfanyl]-4,6-dimethylquinazoline
CAS 498536-90-6C17H15ClN2S
2-(Benzylsulfanyl)-4,6,8-trimethylquinazoline chemical structure, C18H18N2S, CAS 488716-75-2
2-(Benzylsulfanyl)-4,6,8-trimethylquinazoline
CAS 488716-75-2C18H18N2S
4,6,8-Trimethyl-2-[(4-nitrophenyl)methylsulfanyl]quinazoline chemical structure, C18H17N3O2S, CAS 488860-25-9
4,6,8-Trimethyl-2-[(4-nitrophenyl)methylsulfanyl]quinazoline
CAS 488860-25-9C18H17N3O2S
6-Ethoxy-4-methyl-2-[(3-methylbenzyl)sulfanyl]quinazoline chemical structure, C19H20N2OS, CAS 500146-25-8
6-Ethoxy-4-methyl-2-[(3-methylbenzyl)sulfanyl]quinazoline
CAS 500146-25-8C19H20N2OS
2-[(4-Chlorobenzyl)thio]-4,6,8-trimethylquinazoline chemical structure, C18H17ClN2S, CAS 488842-49-5
2-[(4-Chlorobenzyl)thio]-4,6,8-trimethylquinazoline
CAS 488842-49-5C18H17ClN2S
4,6,7-Trimethyl-2-[(4-methylbenzyl)sulfanyl]quinazoline chemical structure, C19H20N2S, CAS 497245-60-0
4,6,7-Trimethyl-2-[(4-methylbenzyl)sulfanyl]quinazoline
CAS 497245-60-0C19H20N2S
6-Ethoxy-2-({4-nitrobenzyl}sulfanyl)-4-methylquinazoline chemical structure, C18H17N3O3S, CAS 351225-40-6
6-Ethoxy-2-({4-nitrobenzyl}sulfanyl)-4-methylquinazoline
CAS 351225-40-6C18H17N3O3S
2-[(4-Bromobenzyl)sulfanyl]-4,6,7-trimethylquinazoline chemical structure, C18H17BrN2S, CAS 488088-37-5
2-[(4-Bromobenzyl)sulfanyl]-4,6,7-trimethylquinazoline
CAS 488088-37-5C18H17BrN2S
2-[(4-Bromobenzyl)sulfanyl]-6-methoxy-4-methylquinazoline chemical structure, C17H15BrN2OS, CAS 496772-93-1
2-[(4-Bromobenzyl)sulfanyl]-6-methoxy-4-methylquinazoline
CAS 496772-93-1C17H15BrN2OS