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Murcko scaffold

Ring system with 3 rings and 19 atoms

98 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
98
With full pages
44
Scaffold SMILES

O=C(Nc1ccc2c(c1)OCCO2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc2c(c1)OCCO2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 98 chemicals

N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methoxybenzamide chemical structure, C16H15NO4, CAS 331989-06-1
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methoxybenzamide
CAS 331989-06-1C16H15NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxy-3-nitrobenzamide chemical structure, C16H14N2O6, CAS 347319-72-6
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxy-3-nitrobenzamide
CAS 347319-72-6C16H14N2O6
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4,6-trimethylbenzamide chemical structure, C18H19NO3, CAS 301306-96-7
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4,6-trimethylbenzamide
CAS 301306-96-7C18H19NO3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzamide chemical structure, C16H15NO4, CAS 299955-83-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzamide
CAS 299955-83-2C16H15NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-fluorobenzamide chemical structure, C15H12FNO3, CAS 347335-57-3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-fluorobenzamide
CAS 347335-57-3C15H12FNO3
4-Chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide chemical structure, C15H12ClNO3, CAS 301306-91-2
4-Chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide
CAS 301306-91-2C15H12ClNO3
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide chemical structure, C15H12ClNO3, CAS 301306-92-3
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide
CAS 301306-92-3C15H12ClNO3
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide chemical structure, C15H12ClNO3, CAS 301306-93-4
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide
CAS 301306-93-4C15H12ClNO3
4-Bromo-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide chemical structure, C15H12BrNO3, CAS 301306-94-5
4-Bromo-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide
CAS 301306-94-5C15H12BrNO3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzamide chemical structure, C15H12N2O5, CAS 5681-10-7
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzamide
CAS 5681-10-7C15H12N2O5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methylbenzamide chemical structure, C16H15NO3, CAS 301306-97-8
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methylbenzamide
CAS 301306-97-8C16H15NO3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methylbenzamide chemical structure, C16H15NO3, CAS 301306-98-9
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-methylbenzamide
CAS 301306-98-9C16H15NO3
2,4-Dichloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide chemical structure, C15H11Cl2NO3, CAS 301306-99-0
2,4-Dichloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)benzamide
CAS 301306-99-0C15H11Cl2NO3
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzamide chemical structure, C15H11ClN2O5, CAS 289494-20-8
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-nitrobenzamide
CAS 289494-20-8C15H11ClN2O5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-ethoxybenzamide chemical structure, C17H17NO4, CAS 332922-64-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-ethoxybenzamide
CAS 332922-64-2C17H17NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,6-dimethoxybenzamide chemical structure, C17H17NO5, CAS 340219-91-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,6-dimethoxybenzamide
CAS 340219-91-2C17H17NO5
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzamide chemical structure, C16H14ClNO4, CAS 347319-67-9
3-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methoxybenzamide
CAS 347319-67-9C16H14ClNO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3,5-dimethoxybenzamide chemical structure, C17H17NO5, CAS 420824-70-0
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3,5-dimethoxybenzamide
CAS 420824-70-0C17H17NO5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methyl-4-nitrobenzamide chemical structure, C16H14N2O5, CAS 347337-49-9
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-methyl-4-nitrobenzamide
CAS 347337-49-9C16H14N2O5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-nitrobenzamide chemical structure, C15H12N2O5, CAS 403643-64-1
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-nitrobenzamide
CAS 403643-64-1C15H12N2O5
5-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methoxybenzamide chemical structure, C16H14ClNO4, CAS 321533-12-4
5-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methoxybenzamide
CAS 321533-12-4C16H14ClNO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-ethoxybenzamide chemical structure, C17H17NO4, CAS 346726-16-7
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-ethoxybenzamide
CAS 346726-16-7C17H17NO4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methylsulfanylbenzamide chemical structure, C16H15NO3S, CAS 341020-16-4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methylsulfanylbenzamide
CAS 341020-16-4C16H15NO3S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methoxy-4-methylsulfanylbenzamide chemical structure, C17H17NO4S, CAS 299921-61-2
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methoxy-4-methylsulfanylbenzamide
CAS 299921-61-2C17H17NO4S