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Murcko scaffold

Ring system with 3 rings and 19 atoms

119 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
119
With full pages
32
Scaffold SMILES

O=c1[nH]c(C=Cc2ccccc2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(C=Cc2ccccc2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 119 chemicals

3-Methyl-2-[2-(2-methylphenyl)ethenyl]quinazolin-4-one chemical structure, C18H16N2O, CAS 429621-53-4
3-Methyl-2-[2-(2-methylphenyl)ethenyl]quinazolin-4-one
CAS 429621-53-4C18H16N2O
2-(2-Chlorostyryl)-3-ethyl-6-iodoquinazolin-4(3H)-one chemical structure, C18H14ClIN2O
2-(2-Chlorostyryl)-3-ethyl-6-iodoquinazolin-4(3H)-one
C18H14ClIN2O
3-Ethyl-6-iodo-2-(4-methoxystyryl)quinazolin-4(3H)-one chemical structure, C19H17IN2O2
3-Ethyl-6-iodo-2-(4-methoxystyryl)quinazolin-4(3H)-one
C19H17IN2O2
3-Ethyl-6-iodo-2-(4-methylstyryl)quinazolin-4(3H)-one chemical structure, C19H17IN2O, CAS 500104-49-4
3-Ethyl-6-iodo-2-(4-methylstyryl)quinazolin-4(3H)-one
CAS 500104-49-4C19H17IN2O
3-Ethyl-2-(4-hydroxystyryl)-6-iodoquinazolin-4(3H)-one chemical structure, C18H15IN2O2, CAS 487014-81-3
3-Ethyl-2-(4-hydroxystyryl)-6-iodoquinazolin-4(3H)-one
CAS 487014-81-3C18H15IN2O2
6-Iodo-2-(4-methoxystyryl)-3-methylquinazolin-4(3H)-one chemical structure, C18H15IN2O2, CAS 799825-46-0
6-Iodo-2-(4-methoxystyryl)-3-methylquinazolin-4(3H)-one
CAS 799825-46-0C18H15IN2O2
4(3H)-Quinazolinone, 3-amino-2-(2-phenylethenyl)- chemical structure, C16H13N3O
4(3H)-Quinazolinone, 3-amino-2-(2-phenylethenyl)-
C16H13N3O
3-Ethyl-6-iodo-2-[(E)-2-(4-methoxyphenyl)ethenyl]quinazolin-4-one chemical structure, C19H17IN2O2, CAS 695220-14-5
3-Ethyl-6-iodo-2-[(E)-2-(4-methoxyphenyl)ethenyl]quinazolin-4-one
CAS 695220-14-5C19H17IN2O2
3-Ethyl-2-[(E)-2-(4-nitrophenyl)ethenyl]quinazolin-4-one chemical structure, C18H15N3O3, CAS 334505-43-0
3-Ethyl-2-[(E)-2-(4-nitrophenyl)ethenyl]quinazolin-4-one
CAS 334505-43-0C18H15N3O3
3-Methyl-2-[(E)-2-(2-nitrophenyl)ethenyl]quinazolin-4-one chemical structure, C17H13N3O3, CAS 56478-64-9
3-Methyl-2-[(E)-2-(2-nitrophenyl)ethenyl]quinazolin-4-one
CAS 56478-64-9C17H13N3O3
RefChem:388709 chemical structure, C17H13N3O3, CAS 5903-61-7
RefChem:388709
CAS 5903-61-7C17H13N3O3
2-[(E)-2-(3-Bromophenyl)ethenyl]-3-methylquinazolin-4-one chemical structure, C17H13BrN2O, CAS 337352-11-1
2-[(E)-2-(3-Bromophenyl)ethenyl]-3-methylquinazolin-4-one
CAS 337352-11-1C17H13BrN2O
3-Methyl-2-[(E)-2-phenylethenyl]quinazolin-4-one chemical structure, C17H14N2O, CAS 56478-61-6
3-Methyl-2-[(E)-2-phenylethenyl]quinazolin-4-one
CAS 56478-61-6C17H14N2O
2-(2-{3-Nitrophenyl}vinyl)-3-methyl-4(3H)-quinazolinone chemical structure, C17H13N3O3, CAS 56478-70-7
2-(2-{3-Nitrophenyl}vinyl)-3-methyl-4(3H)-quinazolinone
CAS 56478-70-7C17H13N3O3
3-Ethyl-2-[(E)-2-(3-nitrophenyl)ethenyl]quinazolin-4-one chemical structure, C18H15N3O3, CAS 72005-25-5
3-Ethyl-2-[(E)-2-(3-nitrophenyl)ethenyl]quinazolin-4-one
CAS 72005-25-5C18H15N3O3
3-Ethyl-2-[(E)-2-phenylethenyl]quinazolin-4-one chemical structure, C18H16N2O, CAS 1195615-34-9
3-Ethyl-2-[(E)-2-phenylethenyl]quinazolin-4-one
CAS 1195615-34-9C18H16N2O
3-Ethyl-2-[(E)-2-(2-fluorophenyl)ethenyl]quinazolin-4-one chemical structure, C18H15FN2O, CAS 1351482-96-6
3-Ethyl-2-[(E)-2-(2-fluorophenyl)ethenyl]quinazolin-4-one
CAS 1351482-96-6C18H15FN2O
3-Ethyl-2-[(E)-2-(2-nitrophenyl)ethenyl]quinazolin-4-one chemical structure, C18H15N3O3, CAS 50830-14-3
3-Ethyl-2-[(E)-2-(2-nitrophenyl)ethenyl]quinazolin-4-one
CAS 50830-14-3C18H15N3O3
3-Ethyl-2-[(E)-2-(4-methoxyphenyl)ethenyl]quinazolin-4-one chemical structure, C19H18N2O2, CAS 1447925-39-4
3-Ethyl-2-[(E)-2-(4-methoxyphenyl)ethenyl]quinazolin-4-one
CAS 1447925-39-4C19H18N2O2
2-[(E)-2-(3-Bromophenyl)ethenyl]-3-ethylquinazolin-4-one chemical structure, C18H15BrN2O, CAS 304880-70-4
2-[(E)-2-(3-Bromophenyl)ethenyl]-3-ethylquinazolin-4-one
CAS 304880-70-4C18H15BrN2O
2-[(E)-2-(4-Chlorophenyl)ethenyl]-3-ethylquinazolin-4-one chemical structure, C18H15ClN2O, CAS 37649-22-2
2-[(E)-2-(4-Chlorophenyl)ethenyl]-3-ethylquinazolin-4-one
CAS 37649-22-2C18H15ClN2O
2-[(E)-2-(4-Bromophenyl)ethenyl]-3-ethylquinazolin-4-one chemical structure, C18H15BrN2O, CAS 312585-75-4
2-[(E)-2-(4-Bromophenyl)ethenyl]-3-ethylquinazolin-4-one
CAS 312585-75-4C18H15BrN2O
2-[(E)-2-(3-Bromophenyl)ethenyl]-3-(2-hydroxyethyl)quinazolin-4-one chemical structure, C18H15BrN2O2, CAS 335203-73-1
2-[(E)-2-(3-Bromophenyl)ethenyl]-3-(2-hydroxyethyl)quinazolin-4-one
CAS 335203-73-1C18H15BrN2O2
2-[2-(4-Bromophenyl)vinyl]-3-(2-hydroxyethyl)-4(3H)-quinazolinone chemical structure, C18H15BrN2O2, CAS 335203-74-2
2-[2-(4-Bromophenyl)vinyl]-3-(2-hydroxyethyl)-4(3H)-quinazolinone
CAS 335203-74-2C18H15BrN2O2