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Murcko scaffold

N-Phenyl-2,3-dihydro-1,4-benzodioxine-2-carboxamide scaffold

95 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
95
With full pages
47
Scaffold SMILES

O=C(Nc1ccccc1)C1COc2ccccc2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2,3-dihydro-1,4-benzodioxine-2-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)C1COc2ccccc2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 95 chemicals

N-(4-Chloro-2,5-dimethoxyphenyl)-2,3-dihydro-1,4-benzodioxine-3-carboxamide chemical structure, C17H16ClNO5, CAS 304888-25-3
N-(4-Chloro-2,5-dimethoxyphenyl)-2,3-dihydro-1,4-benzodioxine-3-carboxamide
CAS 304888-25-3C17H16ClNO5
Methyl 2-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoate chemical structure, C17H15NO5, CAS 304888-63-9
Methyl 2-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoate
CAS 304888-63-9C17H15NO5
2-Methoxyethyl 4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoate chemical structure, C19H19NO6, CAS 301689-34-9
2-Methoxyethyl 4-[(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)amino]benzoate
CAS 301689-34-9C19H19NO6
2,3-Dihydro-benzo[1,4]dioxine-2-carboxylic acid (4-carbamoyl-phenyl)-amide chemical structure, C16H14N2O4, CAS 5856-51-9
2,3-Dihydro-benzo[1,4]dioxine-2-carboxylic acid (4-carbamoyl-phenyl)-amide
CAS 5856-51-9C16H14N2O4
N-(2-Carbamoylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H14N2O4, CAS 302550-45-4
N-(2-Carbamoylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 302550-45-4C16H14N2O4
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H11ClF3NO3, CAS 6110-68-5
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 6110-68-5C16H11ClF3NO3
N-(4-Sulfamoylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide chemical structure, C15H14N2O5S, CAS 300818-20-6
N-(4-Sulfamoylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
CAS 300818-20-6C15H14N2O5S
N-(4-Fluorophenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C15H12FNO3, CAS 294853-27-3
N-(4-Fluorophenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 294853-27-3C15H12FNO3
N-(2-Fluorophenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C15H12FNO3, CAS 304888-20-8
N-(2-Fluorophenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-20-8C15H12FNO3
N-(4-Butylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C19H21NO3, CAS 304888-21-9
N-(4-Butylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-21-9C19H21NO3
N-(2-Ethyl-6-methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C18H19NO3, CAS 304888-22-0
N-(2-Ethyl-6-methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-22-0C18H19NO3
2H,3H-Benzo[e]1,4-dioxan-2-yl-N-[2-(methylethyl)phenyl]carboxamide chemical structure, C18H19NO3, CAS 304888-24-2
2H,3H-Benzo[e]1,4-dioxan-2-yl-N-[2-(methylethyl)phenyl]carboxamide
CAS 304888-24-2C18H19NO3
N-(2,5-Dimethoxyphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C17H17NO5, CAS 6049-07-6
N-(2,5-Dimethoxyphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 6049-07-6C17H17NO5
N-(2,4-Dimethoxyphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C17H17NO5, CAS 304888-27-5
N-(2,4-Dimethoxyphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-27-5C17H17NO5
N-(3-Methoxyphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H15NO4, CAS 5931-46-4
N-(3-Methoxyphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 5931-46-4C16H15NO4
N-[2-(Trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H12F3NO3, CAS 304888-42-4
N-[2-(Trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-42-4C16H12F3NO3
N-[3-(Trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H12F3NO3, CAS 294853-44-4
N-[3-(Trifluoromethyl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 294853-44-4C16H12F3NO3
N-(2-Bromo-4-methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H14BrNO3, CAS 304888-43-5
N-(2-Bromo-4-methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-43-5C16H14BrNO3
2,3-Dihydro-N-(2-methylphenyl)-1,4-benzodioxin-2-carboxamide chemical structure, C16H15NO3, CAS 304888-45-7
2,3-Dihydro-N-(2-methylphenyl)-1,4-benzodioxin-2-carboxamide
CAS 304888-45-7C16H15NO3
N-(3-Methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H15NO3, CAS 294853-48-8
N-(3-Methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 294853-48-8C16H15NO3
N-(4-Methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C16H15NO3, CAS 304888-46-8
N-(4-Methylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-46-8C16H15NO3
N-(2,4-Dimethylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C17H17NO3, CAS 304888-47-9
N-(2,4-Dimethylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-47-9C17H17NO3
N-(3,4-Dimethylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C17H17NO3, CAS 6049-30-5
N-(3,4-Dimethylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 6049-30-5C17H17NO3
N-(2,5-Dimethylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide chemical structure, C17H17NO3, CAS 304888-49-1
N-(2,5-Dimethylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
CAS 304888-49-1C17H17NO3