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Murcko scaffold

Ring system with 2 rings and 12 atoms

103 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
103
With full pages
22
Scaffold SMILES

c1ccc(Cc2nncs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2nncs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 103 chemicals

5-(3-Methylbenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C10H11N3S, CAS 39181-46-9
5-(3-Methylbenzyl)-1,3,4-thiadiazol-2-amine
CAS 39181-46-9C10H11N3S
5-(3,4-Dichlorobenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C9H7Cl2N3S, CAS 39181-51-6
5-(3,4-Dichlorobenzyl)-1,3,4-thiadiazol-2-amine
CAS 39181-51-6C9H7Cl2N3S
5-(4-Bromobenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C9H8BrN3S, CAS 329921-62-2
5-(4-Bromobenzyl)-1,3,4-thiadiazol-2-amine
CAS 329921-62-2C9H8BrN3S
5-(2,4-Dichlorobenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C9H7Cl2N3S, CAS 39181-52-7
5-(2,4-Dichlorobenzyl)-1,3,4-thiadiazol-2-amine
CAS 39181-52-7C9H7Cl2N3S
5-(4-Nitrobenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C9H8N4O2S, CAS 247225-84-9
5-(4-Nitrobenzyl)-1,3,4-thiadiazol-2-amine
CAS 247225-84-9C9H8N4O2S
N-[5-(4-Chlorobenzyl)-1,3,4-thiadiazol-2-yl]methanesulfonamide chemical structure, C10H10ClN3O2S2, CAS 590398-64-4
N-[5-(4-Chlorobenzyl)-1,3,4-thiadiazol-2-yl]methanesulfonamide
CAS 590398-64-4C10H10ClN3O2S2
2,2-Dichloro-N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H11Cl2N3O2S, CAS 581780-14-5
2,2-Dichloro-N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 581780-14-5C12H11Cl2N3O2S
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-3,3-dimethylbutanamide chemical structure, C16H21N3O2S, CAS 510736-62-6
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-3,3-dimethylbutanamide
CAS 510736-62-6C16H21N3O2S
5-(4-Chlorobenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C9H8ClN3S, CAS 39181-43-6
5-(4-Chlorobenzyl)-1,3,4-thiadiazol-2-amine
CAS 39181-43-6C9H8ClN3S
5-(3,4-Dimethoxybenzyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3O2S, CAS 313957-85-6
5-(3,4-Dimethoxybenzyl)-1,3,4-thiadiazol-2-amine
CAS 313957-85-6C11H13N3O2S
5-[(2-Fluorophenyl)methyl]-1,3,4-thiadiazol-2-amine chemical structure, C9H8FN3S, CAS 39181-53-8
5-[(2-Fluorophenyl)methyl]-1,3,4-thiadiazol-2-amine
CAS 39181-53-8C9H8FN3S
5-[(4-Fluorophenyl)methyl]-1,3,4-thiadiazol-2-amine chemical structure, C9H8FN3S, CAS 39181-55-0
5-[(4-Fluorophenyl)methyl]-1,3,4-thiadiazol-2-amine
CAS 39181-55-0C9H8FN3S
5-[(3-Bromophenyl)methyl]-1,3,4-thiadiazol-2-amine chemical structure, C9H8BrN3S, CAS 299936-23-5
5-[(3-Bromophenyl)methyl]-1,3,4-thiadiazol-2-amine
CAS 299936-23-5C9H8BrN3S
5-Benzyl-1,3,4-thiadiazol-2-amine chemical structure, C9H9N3S, CAS 16502-08-2
5-Benzyl-1,3,4-thiadiazol-2-amine
CAS 16502-08-2C9H9N3S
2-Methoxy-N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C13H15N3O3S, CAS 510737-11-8
2-Methoxy-N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]acetamide
CAS 510737-11-8C13H15N3O3S
5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-amine chemical structure, C10H11N3OS, CAS 63617-18-5
5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-amine
CAS 63617-18-5C10H11N3OS
N-[5-(2,4-Dichlorobenzyl)-1,3,4-thiadiazol-2-yl]-3-methylbutanamide chemical structure, C14H15Cl2N3OS, CAS 332407-83-7
N-[5-(2,4-Dichlorobenzyl)-1,3,4-thiadiazol-2-yl]-3-methylbutanamide
CAS 332407-83-7C14H15Cl2N3OS
Ethyl (5-benzyl-1,3,4-thiadiazol-2-yl)carbamate chemical structure, C12H13N3O2S, CAS 62441-45-6
Ethyl (5-benzyl-1,3,4-thiadiazol-2-yl)carbamate
CAS 62441-45-6C12H13N3O2S
2-Ethyl-N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]butanamide chemical structure, C16H21N3O2S, CAS 587844-48-2
2-Ethyl-N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]butanamide
CAS 587844-48-2C16H21N3O2S
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]butanamide chemical structure, C14H17N3O2S, CAS 701218-45-3
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]butanamide
CAS 701218-45-3C14H17N3O2S
N-[5-(3-Bromobenzyl)-1,3,4-thiadiazol-2-yl]-2-methylpropanamide chemical structure, C13H14BrN3OS, CAS 310418-62-3
N-[5-(3-Bromobenzyl)-1,3,4-thiadiazol-2-yl]-2-methylpropanamide
CAS 310418-62-3C13H14BrN3OS
N-[5-[(4-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methoxyacetamide chemical structure, C12H12ClN3O2S, CAS 636994-53-1
N-[5-[(4-Chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methoxyacetamide
CAS 636994-53-1C12H12ClN3O2S
2,2,2-Trichloro-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H7Cl4N3OS, CAS 590399-36-3
2,2,2-Trichloro-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]acetamide
CAS 590399-36-3C11H7Cl4N3OS
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methylpropanamide chemical structure, C14H17N3O2S, CAS 713092-32-1
N-[5-[(4-Methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methylpropanamide
CAS 713092-32-1C14H17N3O2S