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Murcko scaffold

Ring system with 2 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
12
With full pages
5
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1ccsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1ccsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N-[(E)-1-[4-(Methanesulfonamido)phenyl]ethylideneamino]-5-propylthiophene-3-carboxamide chemical structure, C17H21N3O3S2, CAS 522620-81-1
N-[(E)-1-[4-(Methanesulfonamido)phenyl]ethylideneamino]-5-propylthiophene-3-carboxamide
CAS 522620-81-1C17H21N3O3S2
N-[(E)-(4-tert-Butylphenyl)methylideneamino]-4,5-dimethylthiophene-3-carboxamide chemical structure, C18H22N2OS, CAS 445244-98-4
N-[(E)-(4-tert-Butylphenyl)methylideneamino]-4,5-dimethylthiophene-3-carboxamide
CAS 445244-98-4C18H22N2OS
N'-(2,4-Diethoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide chemical structure, C18H22N2O3S, CAS 492439-22-2
N'-(2,4-Diethoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide
CAS 492439-22-2C18H22N2O3S
N'-(4-Butoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide chemical structure, C18H22N2O2S, CAS 445245-03-4
N'-(4-Butoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide
CAS 445245-03-4C18H22N2O2S
N-[(E)-(2-Chlorophenyl)methylideneamino]-4,5-dimethylthiophene-3-carboxamide chemical structure, C14H13ClN2OS, CAS 445245-06-7
N-[(E)-(2-Chlorophenyl)methylideneamino]-4,5-dimethylthiophene-3-carboxamide
CAS 445245-06-7C14H13ClN2OS
N'-(3-Butoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide chemical structure, C18H22N2O2S, CAS 445245-07-8
N'-(3-Butoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide
CAS 445245-07-8C18H22N2O2S
N'-(4-Isobutoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide chemical structure, C18H22N2O2S, CAS 445245-10-3
N'-(4-Isobutoxybenzylidene)-4,5-dimethyl-3-thiophenecarbohydrazide
CAS 445245-10-3C18H22N2O2S
4,5-Dimethyl-N'-(3-propoxybenzylidene)-3-thiophenecarbohydrazide chemical structure, C17H20N2O2S, CAS 445247-01-8
4,5-Dimethyl-N'-(3-propoxybenzylidene)-3-thiophenecarbohydrazide
CAS 445247-01-8C17H20N2O2S
N'-{(E)-[5-chloro-2-(3-methylbutoxy)phenyl]methylidene}-5-propylthiophene-3-carbohydrazide chemical structure, C20H25ClN2O2S, CAS 777875-77-1
N'-{(E)-[5-chloro-2-(3-methylbutoxy)phenyl]methylidene}-5-propylthiophene-3-carbohydrazide
CAS 777875-77-1C20H25ClN2O2S
N'-{(E)-[5-bromo-2-(3-methylbutoxy)phenyl]methylidene}-5-propylthiophene-3-carbohydrazide chemical structure, C20H25BrN2O2S, CAS 777875-79-3
N'-{(E)-[5-bromo-2-(3-methylbutoxy)phenyl]methylidene}-5-propylthiophene-3-carbohydrazide
CAS 777875-79-3C20H25BrN2O2S
5-(Propan-2-yl)-N'-{(E)-[2-(trifluoromethyl)phenyl]methylidene}thiophene-3-carbohydrazide chemical structure, C16H15F3N2OS, CAS 777876-17-2
5-(Propan-2-yl)-N'-{(E)-[2-(trifluoromethyl)phenyl]methylidene}thiophene-3-carbohydrazide
CAS 777876-17-2C16H15F3N2OS
N'-[(E)-(4-Hydroxyphenyl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide chemical structure, C15H16N2O2S, CAS 777876-14-9
N'-[(E)-(4-Hydroxyphenyl)methylidene]-5-(propan-2-yl)thiophene-3-carbohydrazide
CAS 777876-14-9C15H16N2O2S