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Murcko scaffold

2-Phenoxypyrimidine scaffold

351 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
351
With full pages
55
Scaffold SMILES

c1ccc(Oc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenoxypyrimidine page
Murcko scaffold c1ccc(Oc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 351 chemicals

2-((4,6-Dimethoxypyrimidin-2-yl)oxy)benzoic acid chemical structure, C13H12N2O5, CAS 110284-78-1
2-((4,6-Dimethoxypyrimidin-2-yl)oxy)benzoic acid
CAS 110284-78-1C13H12N2O5
2-(4-Chlorophenoxy)pyrimidin-4-amine chemical structure, C10H8ClN3O, CAS 60722-64-7
2-(4-Chlorophenoxy)pyrimidin-4-amine
CAS 60722-64-7C10H8ClN3O
2-(2,4-Difluorophenoxy)pyrimidine chemical structure, C10H6F2N2O, CAS 353258-93-2
2-(2,4-Difluorophenoxy)pyrimidine
CAS 353258-93-2C10H6F2N2O
5-Bromo-2-phenoxypyrimidine chemical structure, C10H7BrN2O, CAS 257280-25-4
5-Bromo-2-phenoxypyrimidine
CAS 257280-25-4C10H7BrN2O
N-{4-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]phenyl}acetamide chemical structure, C14H15N3O4, CAS 329699-64-1
N-{4-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]phenyl}acetamide
CAS 329699-64-1C14H15N3O4
N-{4-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]phenyl}-N-ethylacetamide chemical structure, C16H19N3O4, CAS 294849-01-7
N-{4-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]phenyl}-N-ethylacetamide
CAS 294849-01-7C16H19N3O4
4-((4,6-Dimethylpyrimidin-2-yl)oxy)aniline chemical structure, C12H13N3O, CAS 55749-90-1
4-((4,6-Dimethylpyrimidin-2-yl)oxy)aniline
CAS 55749-90-1C12H13N3O
Methyl 4-(4-methoxy-6-methylpyrimidin-2-yl)oxybenzoate chemical structure, C14H14N2O4, CAS 383895-10-1
Methyl 4-(4-methoxy-6-methylpyrimidin-2-yl)oxybenzoate
CAS 383895-10-1C14H14N2O4
3-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]benzaldehyde chemical structure, C13H12N2O4, CAS 491871-35-3
3-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]benzaldehyde
CAS 491871-35-3C13H12N2O4
4-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]benzaldehyde chemical structure, C13H12N2O4, CAS 491871-36-4
4-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]benzaldehyde
CAS 491871-36-4C13H12N2O4
Benzaldehyde, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]- chemical structure, C13H12N2O4, CAS 110284-76-9
Benzaldehyde, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-
CAS 110284-76-9C13H12N2O4
4-Methoxy-2-phenoxypyrimidine chemical structure, C11H10N2O2, CAS 380626-89-1
4-Methoxy-2-phenoxypyrimidine
CAS 380626-89-1C11H10N2O2
2-(4-Fluorophenoxy)pyrimidine chemical structure, C10H7FN2O, CAS 271793-71-6
2-(4-Fluorophenoxy)pyrimidine
CAS 271793-71-6C10H7FN2O
4-(Pyrimidin-2-yloxy)benzonitrile chemical structure, C11H7N3O, CAS 353259-03-7
4-(Pyrimidin-2-yloxy)benzonitrile
CAS 353259-03-7C11H7N3O
2-(4-Nitrophenoxy)pyrimidine chemical structure, C10H7N3O3, CAS 181801-29-6
2-(4-Nitrophenoxy)pyrimidine
CAS 181801-29-6C10H7N3O3
Benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-, methyl ester chemical structure, C14H14N2O5, CAS 110284-90-7
Benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-, methyl ester
CAS 110284-90-7C14H14N2O5
Methyl 5-chloro-2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]benzoate chemical structure, C14H13ClN2O5, CAS 113784-00-2
Methyl 5-chloro-2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]benzoate
CAS 113784-00-2C14H13ClN2O5
1-[4-Methyl-2-(2,4,5-trichlorophenoxy)-5-pyrimidinyl]-1-ethanone chemical structure, C13H9Cl3N2O2, CAS 478047-63-1
1-[4-Methyl-2-(2,4,5-trichlorophenoxy)-5-pyrimidinyl]-1-ethanone
CAS 478047-63-1C13H9Cl3N2O2
1-[2-(2,5-Dichlorophenoxy)-4-methyl-5-pyrimidinyl]-1-ethanone chemical structure, C13H10Cl2N2O2, CAS 478047-64-2
1-[2-(2,5-Dichlorophenoxy)-4-methyl-5-pyrimidinyl]-1-ethanone
CAS 478047-64-2C13H10Cl2N2O2
2-(2,5-Dichlorophenoxy)-4-methoxy-6-(trifluoromethyl)pyrimidine chemical structure, C12H7Cl2F3N2O2, CAS 478047-76-6
2-(2,5-Dichlorophenoxy)-4-methoxy-6-(trifluoromethyl)pyrimidine
CAS 478047-76-6C12H7Cl2F3N2O2
4-Methoxy-2-(2,4,5-trichlorophenoxy)-6-(trifluoromethyl)pyrimidine chemical structure, C12H6Cl3F3N2O2, CAS 478047-77-7
4-Methoxy-2-(2,4,5-trichlorophenoxy)-6-(trifluoromethyl)pyrimidine
CAS 478047-77-7C12H6Cl3F3N2O2
2-(4-Methoxyphenoxy)-5-pyrimidinecarbonitrile chemical structure, C12H9N3O2, CAS 400086-00-2
2-(4-Methoxyphenoxy)-5-pyrimidinecarbonitrile
CAS 400086-00-2C12H9N3O2
4-(Pyrimidin-2-yloxy)aniline chemical structure, C10H9N3O, CAS 105130-26-5
4-(Pyrimidin-2-yloxy)aniline
CAS 105130-26-5C10H9N3O
2-(4-Iodophenoxy)pyrimidine chemical structure, C10H7IN2O, CAS 330792-86-4
2-(4-Iodophenoxy)pyrimidine
CAS 330792-86-4C10H7IN2O