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Murcko scaffold

Ring system with 2 rings and 13 atoms

71 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
71
With full pages
10
Scaffold SMILES

O=c1ccn(C2C=CCO2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2C=CCO2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 71 chemicals

1-[5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C10H12N2O4, CAS 26638-87-9
1-[5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 26638-87-9C10H12N2O4
Stavudine chemical structure, C10H12N2O4, CAS 3056-17-5
Stavudine
CAS 3056-17-5C10H12N2O4
2',3'-Didehydro-2',3'-dideoxyuridine chemical structure, C9H10N2O4, CAS 5974-93-6
2',3'-Didehydro-2',3'-dideoxyuridine
CAS 5974-93-6C9H10N2O4
2',3'-Dideoxy-2',3'-dehydrothymidine 5'-triphosphate chemical structure, C10H15N2O13P3, CAS 26194-89-8
2',3'-Dideoxy-2',3'-dehydrothymidine 5'-triphosphate
CAS 26194-89-8C10H15N2O13P3
3'-Deoxy-2',3'-didehydro-2'fluorothymidine chemical structure, C10H11FN2O4, CAS 122757-54-4
3'-Deoxy-2',3'-didehydro-2'fluorothymidine
CAS 122757-54-4C10H11FN2O4
Thymidine, 2',3'-didehydro- chemical structure, C10H12N2O5, CAS 64295-01-8
Thymidine, 2',3'-didehydro-
CAS 64295-01-8C10H12N2O5
Thymidine, 2',3'-didehydro-alpha,alpha,alpha-trifluoro- chemical structure, C10H9F3N2O5, CAS 64381-92-6
Thymidine, 2',3'-didehydro-alpha,alpha,alpha-trifluoro-
CAS 64381-92-6C10H9F3N2O5
2'-Chloro-2',3'-dideoxyuridinene chemical structure, C9H9ClN2O4, CAS 115259-92-2
2'-Chloro-2',3'-dideoxyuridinene
CAS 115259-92-2C9H9ClN2O4
2',3'-Didehydro-2',3'-dideoxy-5-hydroxymethyluridine chemical structure, C10H12N2O5, CAS 158532-72-0
2',3'-Didehydro-2',3'-dideoxy-5-hydroxymethyluridine
CAS 158532-72-0C10H12N2O5
Uridine, 2',3'-didehydro-2',3'-dideoxy-5-ethyl- chemical structure, C11H14N2O4, CAS 117723-56-5
Uridine, 2',3'-didehydro-2',3'-dideoxy-5-ethyl-
CAS 117723-56-5C11H14N2O4
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-acetate chemical structure, C12H14N2O5, CAS 77421-68-2
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-acetate
CAS 77421-68-2C12H14N2O5
5-Chloro-2',3'-didehydro-2',3'-dideoxyuridine chemical structure, C9H9ClN2O4, CAS 120815-05-6
5-Chloro-2',3'-didehydro-2',3'-dideoxyuridine
CAS 120815-05-6C9H9ClN2O4
Thymidine, 2',3'-didehydro-3'-deoxy-3'-fluoro- chemical structure, C10H11FN2O4, CAS 121354-03-8
Thymidine, 2',3'-didehydro-3'-deoxy-3'-fluoro-
CAS 121354-03-8C10H11FN2O4
Thymidine, 3'-deoxy-2',3'-didehydro-3'-methyl- chemical structure, C11H14N2O4, CAS 118744-88-0
Thymidine, 3'-deoxy-2',3'-didehydro-3'-methyl-
CAS 118744-88-0C11H14N2O4
3-Furancarbonitrile, 5-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-2,5-dihydro-2-(hydroxymethyl)-, (2S,5R)- chemical structure, C11H11N3O4, CAS 118222-08-5
3-Furancarbonitrile, 5-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-2,5-dihydro-2-(hydroxymethyl)-, (2S,5R)-
CAS 118222-08-5C11H11N3O4
Uridine, 2',3'-didehydro-2'-fluoro- chemical structure, C9H9FN2O4, CAS 122757-52-2
Uridine, 2',3'-didehydro-2'-fluoro-
CAS 122757-52-2C9H9FN2O4
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-octanoate chemical structure, C18H26N2O5, CAS 134767-53-6
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-octanoate
CAS 134767-53-6C18H26N2O5
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(2,2-dimethylpropanoate) chemical structure, C15H20N2O5, CAS 126209-27-6
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(2,2-dimethylpropanoate)
CAS 126209-27-6C15H20N2O5
Thymidine, 2',3'-didehydro-3'-deoxy-alpha,alpha,alpha-trifluoro- chemical structure, C10H9F3N2O4, CAS 21618-68-8
Thymidine, 2',3'-didehydro-3'-deoxy-alpha,alpha,alpha-trifluoro-
CAS 21618-68-8C10H9F3N2O4
Uridine, 2',3'-didehydro-2',3'-dideoxy-5-iodo- chemical structure, C9H9IN2O4, CAS 144989-72-0
Uridine, 2',3'-didehydro-2',3'-dideoxy-5-iodo-
CAS 144989-72-0C9H9IN2O4
Thymidine, 4'-azido-2',3'-didehydro-3'-deoxy- chemical structure, C10H11N5O4, CAS 140226-08-0
Thymidine, 4'-azido-2',3'-didehydro-3'-deoxy-
CAS 140226-08-0C10H11N5O4
Stavudine monophosphate chemical structure, C10H13N2O7P, CAS 27646-59-9
Stavudine monophosphate
CAS 27646-59-9C10H13N2O7P
Lamivudine, stavudine chemical structure, C18H23N5O7S, CAS 880256-72-4
Lamivudine, stavudine
CAS 880256-72-4C18H23N5O7S
1-[(2R,5R)-4-Fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione chemical structure, C9H9FN2O4, CAS 144433-82-9
1-[(2R,5R)-4-Fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione
CAS 144433-82-9C9H9FN2O4