Murcko scaffold
Ring system with 2 rings and 16 atoms
24 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 24
- With full pages
- 10
Scaffold SMILES
c1ccc(CCCCCC2CCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 24 of 24 chemicals
Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
CAS 155551-81-8C26H40O5
Latanoprost, (5E)-
CAS 913258-34-1C26H40O5
Latanoprost
CAS 130209-82-4C26H40O5
Latanoprost acid
CAS 41639-83-2C23H34O5
trans-Latanoprost Acid
CAS 903549-49-5C23H34O5
Xalacom
CAS 852336-82-4C39H64N4O8S
Latanoprost ethyl amide
CAS 607351-44-0C25H39NO4
![7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]cyclopentyl]heptanoic acid chemical structure, C24H35F3O5, CAS 1027401-98-4](/s/DSVAWVBHUBDAPY-AHJNKEMKSA-N.svg)
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]cyclopentyl]heptanoic acid
CAS 1027401-98-4C24H35F3O5
Latanoprost, (15S)-
CAS 145773-22-4C26H40O5
Latanoprostene bunod
CAS 860005-21-6C27H41NO8
(15S)-Latanoprost acid
CAS 41639-84-3C23H34O5
Latanoprost tris(triethylsilyl) ether
CAS 477884-78-9C44H82O5Si3
Latanoprost acid arginine
CAS 1224443-39-3C29H48N4O7
Propan-2-yl (E)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3S)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
CAS 1235141-39-5C26H40O5
17-Trifluoromethylphenyl-13,14-dihydro trinor prostaglandin F2alpha
CAS 294856-01-2C24H33F3O5
Latanoprost methyl ester
CAS 913258-31-8C24H36O5
RefChem:536080
CAS 1289580-06-8C35H62O5Si2
RefChem:536077
CAS 1240483-23-1C35H62O5Si2
1-(5-Phenylpentyl)cyclopentanecarboxylic acid
CAS 193550-40-2C17H24O2
1,2-Dinor latanoprost acid
CAS 55349-51-4C21H30O5
(E)-Latanoprostene bunod
CAS 2099033-66-4C27H41NO8
Latanoprost (free acid)-d4
CAS 1224443-47-3C23H34O5
![(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenamide chemical structure, C23H35NO4, CAS 919281-21-3](/s/UXOWZBKFWHSZFZ-NFVOFSAMSA-N.svg)
(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenamide
CAS 919281-21-3C23H35NO4
15(S)-latanoprostene bunod
CAS 2099033-64-2C27H41NO8
Related scaffolds
Same ring framework with different atoms or bond orders
C(=CC1CCCC1)CCOc1ccccc137 chemicals
O=C(NCCCn1ccnc1)c1ccccc122 chemicals
O=S(=O)(NCCCn1ccnc1)c1ccccc120 chemicals
O=C(COC(=O)c1ccccc1)NC1CCCC117 chemicals
O=C(COc1ccccc1)NCC1CCCO117 chemicals
S=C(NCCc1ccccc1)Nc1nccs116 chemicals
O=C(CCS(=O)(=O)c1ccccc1)Nc1cccs113 chemicals![Scaffold O=C(CSc1ncn[nH]1)NCc1ccccc1](/scaffold/ZBSYLOJDGBMFAD-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncn[nH]1)NCc1ccccc113 chemicals
O=C(Cn1cccn1)NN=Cc1ccccc112 chemicals
O=C(NCC1CCCO1)C(=O)Nc1ccccc112 chemicals![Scaffold O=C(Cc1ccc[nH]1)NN=Cc1ccccc1](/scaffold/XCXHYNVYLRCCIP-UHFFFAOYSA-N/structure.svg)
O=C(Cc1ccc[nH]1)NN=Cc1ccccc112 chemicals![Scaffold O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n1](/scaffold/GFTUZBZNWRQYBL-UHFFFAOYSA-N/structure.svg)
O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n111 chemicals