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Murcko scaffold

Ring system with 2 rings and 18 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
22
With full pages
14
Scaffold SMILES

O=C(CCc1cn[nH]c1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1cn[nH]c1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

N-[(4-Diethylaminophenyl)methylideneamino]-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanamide chemical structure, C19H27N5O, CAS 5788-62-5
N-[(4-Diethylaminophenyl)methylideneamino]-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanamide
CAS 5788-62-5C19H27N5O
3,5-Dimethyl-1H-pyrazole-4-propanoic acid 2-[(3-bromophenyl)methylene]hydrazide chemical structure, C15H17BrN4O, CAS 634884-73-4
3,5-Dimethyl-1H-pyrazole-4-propanoic acid 2-[(3-bromophenyl)methylene]hydrazide
CAS 634884-73-4C15H17BrN4O
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(E)-(3-hydroxy-4-methoxyphenyl)methylideneamino]propanamide chemical structure, C16H20N4O3, CAS 307321-11-5
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(E)-(3-hydroxy-4-methoxyphenyl)methylideneamino]propanamide
CAS 307321-11-5C16H20N4O3
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanamide chemical structure, C15H16Cl2N4O, CAS 307321-07-9
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanamide
CAS 307321-07-9C15H16Cl2N4O
(E)-Methyl 4-((2-(3-(3,5-dimethyl-1H-pyrazol-4-yl)propanoyl)hydrazono)methyl)benzoate chemical structure, C17H20N4O3, CAS 307321-25-1
(E)-Methyl 4-((2-(3-(3,5-dimethyl-1H-pyrazol-4-yl)propanoyl)hydrazono)methyl)benzoate
CAS 307321-25-1C17H20N4O3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(E)-(3-methoxyphenyl)methylideneamino]propanamide chemical structure, C16H20N4O2, CAS 307321-22-8
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(E)-(3-methoxyphenyl)methylideneamino]propanamide
CAS 307321-22-8C16H20N4O2
N-[(Z)-1-(3,4-Dimethoxyphenyl)ethylideneamino]-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanamide chemical structure, C18H24N4O3, CAS 307321-76-2
N-[(Z)-1-(3,4-Dimethoxyphenyl)ethylideneamino]-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanamide
CAS 307321-76-2C18H24N4O3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(E)-(2-methoxyphenyl)methylideneamino]propanamide chemical structure, C16H20N4O2, CAS 307321-20-6
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(E)-(2-methoxyphenyl)methylideneamino]propanamide
CAS 307321-20-6C16H20N4O2
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(2,4,5-trimethoxybenzylidene)propanehydrazide chemical structure, C18H24N4O4, CAS 5791-74-2
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(2,4,5-trimethoxybenzylidene)propanehydrazide
CAS 5791-74-2C18H24N4O4
(E)-N'-(2,6-Dichlorobenzylidene)-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanehydrazide chemical structure, C15H16Cl2N4O, CAS 307321-26-2
(E)-N'-(2,6-Dichlorobenzylidene)-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanehydrazide
CAS 307321-26-2C15H16Cl2N4O
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(1E)-1-(4-nitrophenyl)ethylidene]propanehydrazide chemical structure, C16H19N5O3, CAS 307321-70-6
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(1E)-1-(4-nitrophenyl)ethylidene]propanehydrazide
CAS 307321-70-6C16H19N5O3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(Z)-1-(3-nitrophenyl)ethylideneamino]propanamide chemical structure, C16H19N5O3, CAS 307321-69-3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-[(Z)-1-(3-nitrophenyl)ethylideneamino]propanamide
CAS 307321-69-3C16H19N5O3
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(3-hydroxybenzylidene)propanehydrazide chemical structure, C15H18N4O2, CAS 307321-12-6
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(3-hydroxybenzylidene)propanehydrazide
CAS 307321-12-6C15H18N4O2
(E)-N'-(3,4-Dimethoxybenzylidene)-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanehydrazide chemical structure, C17H22N4O3, CAS 307321-16-0
(E)-N'-(3,4-Dimethoxybenzylidene)-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanehydrazide
CAS 307321-16-0C17H22N4O3
(E)-N'-(2,5-Dimethoxybenzylidene)-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanehydrazide chemical structure, C17H22N4O3, CAS 634884-78-9
(E)-N'-(2,5-Dimethoxybenzylidene)-3-(3,5-dimethyl-1H-pyrazol-4-yl)propanehydrazide
CAS 634884-78-9C17H22N4O3
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(3,4,5-trimethoxybenzylidene)propanehydrazide chemical structure, C18H24N4O4, CAS 634884-79-0
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(3,4,5-trimethoxybenzylidene)propanehydrazide
CAS 634884-79-0C18H24N4O4
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(4-hydroxybenzylidene)propanehydrazide chemical structure, C15H18N4O2, CAS 307321-03-5
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(4-hydroxybenzylidene)propanehydrazide
CAS 307321-03-5C15H18N4O2
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(4-hydroxy-3-methoxybenzylidene)propanehydrazide chemical structure, C16H20N4O3, CAS 307321-17-1
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(4-hydroxy-3-methoxybenzylidene)propanehydrazide
CAS 307321-17-1C16H20N4O3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(E)-(2-hydroxyphenyl)methylidene]propanehydrazide chemical structure, C15H18N4O2, CAS 307321-04-6
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(E)-(2-hydroxyphenyl)methylidene]propanehydrazide
CAS 307321-04-6C15H18N4O2
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(E)-(3-ethoxy-4-hydroxyphenyl)methylidene]propanehydrazide chemical structure, C17H22N4O3, CAS 307321-19-3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(E)-(3-ethoxy-4-hydroxyphenyl)methylidene]propanehydrazide
CAS 307321-19-3C17H22N4O3
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(3-ethoxy-2-hydroxybenzylidene)propanehydrazide chemical structure, C17H22N4O3, CAS 634884-75-6
(E)-3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-(3-ethoxy-2-hydroxybenzylidene)propanehydrazide
CAS 634884-75-6C17H22N4O3
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]propanehydrazide chemical structure, C16H20N4O3, CAS 634884-76-7
3-(3,5-Dimethyl-1H-pyrazol-4-yl)-N'-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]propanehydrazide
CAS 634884-76-7C16H20N4O3