CompoundList
Sign in
Murcko scaffold

1-[3-(2-Oxopyrrolidin-1-yl)propyl]-3-phenylthiourea scaffold

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
12
With full pages
7
Scaffold SMILES

O=C1CCCN1CCCNC(=S)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[3-(2-Oxopyrrolidin-1-yl)propyl]-3-phenylthiourea page
Murcko scaffold O=C1CCCN1CCCNC(=S)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Ethyl 4-({[3-(2-oxopyrrolidin-1-yl)propyl]carbamothioyl}amino)benzoate chemical structure, C17H23N3O3S, CAS 333758-54-6
Ethyl 4-({[3-(2-oxopyrrolidin-1-yl)propyl]carbamothioyl}amino)benzoate
CAS 333758-54-6C17H23N3O3S
1-(4-Chloro-2-methylphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C15H20ClN3OS, CAS 525581-83-3
1-(4-Chloro-2-methylphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 525581-83-3C15H20ClN3OS
4-[({[3-(2-Oxopyrrolidinyl)propyl]amino}thioxomethyl)amino]benzenesulfonamide chemical structure, C14H20N4O3S2, CAS 525581-86-6
4-[({[3-(2-Oxopyrrolidinyl)propyl]amino}thioxomethyl)amino]benzenesulfonamide
CAS 525581-86-6C14H20N4O3S2
1-(2,4-Dimethoxyphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C16H23N3O3S, CAS 525581-84-4
1-(2,4-Dimethoxyphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 525581-84-4C16H23N3O3S
1-(3,5-Dimethylphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C16H23N3OS, CAS 481697-42-1
1-(3,5-Dimethylphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 481697-42-1C16H23N3OS
1-[3-(2-Oxopyrrolidin-1-yl)propyl]-3-phenylthiourea chemical structure, C14H19N3OS, CAS 332032-86-7
1-[3-(2-Oxopyrrolidin-1-yl)propyl]-3-phenylthiourea
CAS 332032-86-7C14H19N3OS
1-(4-Fluorophenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C14H18FN3OS, CAS 455309-46-3
1-(4-Fluorophenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 455309-46-3C14H18FN3OS
Methyl 4-[[[[3-(2-oxo-1-pyrrolidinyl)propyl]amino]thioxomethyl]amino]benzoate chemical structure, C16H21N3O3S, CAS 774554-08-4
Methyl 4-[[[[3-(2-oxo-1-pyrrolidinyl)propyl]amino]thioxomethyl]amino]benzoate
CAS 774554-08-4C16H21N3O3S
1-(3-Chloro-4-fluorophenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C14H17ClFN3OS, CAS 724777-93-9
1-(3-Chloro-4-fluorophenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 724777-93-9C14H17ClFN3OS
1-(2,4-Dichlorophenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C14H17Cl2N3OS, CAS 473238-27-6
1-(2,4-Dichlorophenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 473238-27-6C14H17Cl2N3OS
1-(2-Methoxyphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C15H21N3O2S, CAS 774187-50-7
1-(2-Methoxyphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 774187-50-7C15H21N3O2S
1-(2,4-Dimethylphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea chemical structure, C16H23N3OS, CAS 525582-61-0
1-(2,4-Dimethylphenyl)-3-[3-(2-oxopyrrolidin-1-yl)propyl]thiourea
CAS 525582-61-0C16H23N3OS