Murcko scaffold
Ring system with 2 rings and 19 atoms
85 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 19
- Chemicals
- 85
- With full pages
- 7
Scaffold SMILES
O=C(CCc1ccccc1)NCC(=O)N1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 85 chemicals
Proctolin
CAS 57966-42-4C30H48N8O8
Somatotropin (32-38)
CAS 97305-48-1C39H60N8O13
Malantide
CAS 86555-35-3C72H124N22O21
Gliadin peptide A (206-217)
CAS 115288-29-4C55H87N19O19
Cyclo(prolyl-alanyl-phenylalanyl-leucyl)
CAS 151545-20-9C23H32N4O4
Sperm-activating peptide 1
CAS 140653-60-7C44H71N11O12S2
pTyr751-Val-Pro-Met-Leu
CAS 145525-99-1C30H48N5O10PS
Cyclo(atsptpal)
CAS 135329-52-1C41H64N12O12
H-Mel-Lys-Pro-Val-NH2
CAS 112983-69-4C29H47Cl2N7O4
Crabrolin
CAS 93207-22-8C74H130N18O14
L-Phenylalanyl-L-seryl-L-proline
CAS 21658-46-8C17H23N3O5
(2S)-1-((2S)-2-(((2S)-2-Amino-3-phenylpropanoyl)amino)propanoyl)pyrrolidine-2-carboxylic acid
CAS 72460-59-4C17H23N3O4
Glycine, L-phenylalanylglycyl-L-prolyl-
CAS 165745-00-6C18H24N4O5
Temporin A
CAS 188713-69-1C68H117N17O14
EE epitope
CAS 221216-83-7C34H50N6O12S2
H-Arg-Tyr(3-OH)-Leu-Pro-Thr-OH
CAS 123413-05-8C30H48N8O9
H-Arg-Phe(4-NH2)-Leu-Pro-Thr-OH
CAS 102430-57-9C30H49N9O7
Ac-hMCH(6-16)-NH2
CAS 1053601-50-5C58H99N21O13S3
Glutamyl-glutamyl-glutamyl-glutamyl-tyrosyl-methionyl-prolyl-methionyl-glutamic acid
CAS 82123-81-7C49H71N9O21S2
![L-Threonine, N-[1-[N-(N-L-lysyl-L-tyrosyl)-L-leucyl]-L-prolyl]- chemical structure, C30H48N6O8, CAS 83162-97-4](/s/YLQIMNRBDJAQKF-LZFDFFMTSA-N.svg)
L-Threonine, N-[1-[N-(N-L-lysyl-L-tyrosyl)-L-leucyl]-L-prolyl]-
CAS 83162-97-4C30H48N6O8
IL-1R Antagonist
CAS 566914-00-9C18H26N2O2
![(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-(4-phosphonooxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoic acid chemical structure, C24H37N4O9PS, CAS 184649-36-3](/s/MCOQGYPLWXQRDE-MUGJNUQGSA-N.svg)
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-Amino-3-(4-phosphonooxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoic acid
CAS 184649-36-3C24H37N4O9PS
O-Phosphono-L-tyrosyl-L-valyl-L-prolyl-L-methionyl-L-leucinamide
CAS 171292-23-2C30H49N6O9PS
![(2S)-1-[2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid chemical structure, C16H21N3O4, CAS 74075-24-4](/s/NPLGQVKZFGJWAI-STQMWFEESA-N.svg)
(2S)-1-[2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid
CAS 74075-24-4C16H21N3O4
- Arg-tyr-leu-pro-thr acetate salt100930-02-7C30H48N8O8
- L-Alanyl-L-tyrosyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-seryl-L-seryl-L-leucine922518-95-4C43H69N9O13
- 1 suppliersPhe-Thr-Pro-Arg-Leu-NH2104191-78-8C30H49N9O6
- l-Tyrosyl-l-valyl-l-prolyl-l-leucine129250-69-7C25H38N4O6
- Elpamotide673478-49-4C47H76N16O13
- Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2157382-69-9C36H56N7O13PS
- Temporin F188713-77-1C68H117N15O14
- Spumigin I1492920-12-3C26H42N6O6
- Keap1-nrf2-IN-161362661-40-2C73H114N16O26
- 1 suppliersMast Cell Degranulating (MCD) Peptide HR-280388-04-1C77H135N17O14
- L-Tyrosyl-L-leucyl-L-prolyl-L-glutamine196085-81-1C25H37N5O7
- L-Lysyl-L-phenylalanyl-O-phosphono-L-threonyl-L-prolyl-L-lysine189827-01-8C30H50N7O10P
- Boc-Phe-Val-Pro-OH101854-25-5C24H35N3O6
- H-Phe-Ser-Pro-Arg-Leu-NH2133082-04-9C29H47N9O6
- Glycyl-L-tyrosyl-L-methionyl-L-prolyl-L-valyl-L-aspartic acid289467-81-8C30H44N6O10S
- Glycyl-L-phenylalanyl-L-seryl-L-proline23827-99-8C19H26N4O6
- N~5~-(Diaminomethylidene)-L-ornithyl-L-glutaminylglycyl-L-tyrosyl-L-seryl-L-prolyl-L-leucine200200-56-2C36H57N11O11
- L-Alanylglycyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-prolyl-L-isoleucine683747-34-4C34H53N7O9
- Ac-Ala-Tyr(3-OH)-Thr-Pro-NH2675154-03-7C23H33N5O8
- L-Leucyl-L-alanyl-L-tyrosyl-L-threonyl-L-prolyl-L-asparaginyl-L-serine649560-79-2C34H52N8O12
- L-Tyrosyl-L-methionyl-L-prolyl-L-valyl-L-cysteinyl-N~5~-(diaminomethylidene)-L-ornithine630104-44-8C33H53N9O8S2
- L-Tyrosyl-L-valyl-L-prolyl-L-valyl-L-threonyl-L-valyl-L-methionyl-L-cysteine628715-90-2C41H66N8O11S2
- L-Tyrosyl-L-leucyl-L-prolyl-L-threonine72273-95-1C24H36N4O7
- N~5~-(Diaminomethylidene)-L-ornithyl-L-phenylalanyl-L-leucyl-L-prolyl-L-threonine72273-89-3C30H48N8O7
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCNC(=S)Nc1ccccc1)c1ccco120 chemicals![Scaffold O=C(CCc1cn[nH]c1)NN=Cc1ccccc1](/scaffold/CJESFXAZXMEJBY-UHFFFAOYSA-N/structure.svg)
O=C(CCc1cn[nH]c1)NN=Cc1ccccc114 chemicals
O=C(CNCCCc1ccccc1)N1CCCC114 chemicals
O=C(COc1ccccc1)NN=Cc1ccco110 chemicals
S=C(NCCCn1ccnc1)Nc1ccccc110 chemicals
O=C(COC(=O)c1cccs1)NCc1ccccc19 chemicals
O=C(CCC(=O)Nc1nncs1)Nc1ccccc18 chemicals
O=C(COC(=O)CC1CCCC1)Nc1ccccc18 chemicals
O=C(CCNC(=O)c1ccco1)Nc1ccccc18 chemicals
O=C(NNC(=S)NCc1ccccc1)c1ccsc17 chemicals
O=C1CCCN1CCCNC(=S)Nc1ccccc17 chemicals
O=C(C=Cc1ccco1)NC(=S)Nc1ccccc17 chemicals