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Murcko scaffold

Ring system with 2 rings and 19 atoms

55 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
55
With full pages
9
Scaffold SMILES

O=C(COC(=O)c1cccs1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1cccs1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

{[(2-Chlorophenyl)methyl]carbamoyl}methyl 5-methylthiophene-2-carboxylate chemical structure, C15H14ClNO3S, CAS 387855-28-9
{[(2-Chlorophenyl)methyl]carbamoyl}methyl 5-methylthiophene-2-carboxylate
CAS 387855-28-9C15H14ClNO3S
[2-[(4-Methoxycarbonylphenyl)methylamino]-2-oxoethyl] thiophene-2-carboxylate chemical structure, C16H15NO5S, CAS 378226-00-7
[2-[(4-Methoxycarbonylphenyl)methylamino]-2-oxoethyl] thiophene-2-carboxylate
CAS 378226-00-7C16H15NO5S
[2-[(2-Methoxyphenyl)methylamino]-2-oxoethyl] thiophene-2-carboxylate chemical structure, C15H15NO4S, CAS 391263-63-1
[2-[(2-Methoxyphenyl)methylamino]-2-oxoethyl] thiophene-2-carboxylate
CAS 391263-63-1C15H15NO4S
[2-[Benzyl(propan-2-yl)amino]-2-oxoethyl] 3-methylthiophene-2-carboxylate chemical structure, C18H21NO3S, CAS 730254-32-7
[2-[Benzyl(propan-2-yl)amino]-2-oxoethyl] 3-methylthiophene-2-carboxylate
CAS 730254-32-7C18H21NO3S
[2-[(4-Chlorophenyl)methylamino]-2-oxoethyl] 3-methylthiophene-2-carboxylate chemical structure, C15H14ClNO3S, CAS 387853-49-8
[2-[(4-Chlorophenyl)methylamino]-2-oxoethyl] 3-methylthiophene-2-carboxylate
CAS 387853-49-8C15H14ClNO3S
2-((4-Methylbenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 733013-19-9
2-((4-Methylbenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate
CAS 733013-19-9C16H17NO3S
[2-[(3,4-Dimethoxyphenyl)methylamino]-2-oxoethyl] 3-methylthiophene-2-carboxylate chemical structure, C17H19NO5S, CAS 735338-32-6
[2-[(3,4-Dimethoxyphenyl)methylamino]-2-oxoethyl] 3-methylthiophene-2-carboxylate
CAS 735338-32-6C17H19NO5S
2-((4-Fluorobenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate chemical structure, C15H14FNO3S, CAS 478824-60-1
2-((4-Fluorobenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate
CAS 478824-60-1C15H14FNO3S
2-((2-Chlorobenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate chemical structure, C15H14ClNO3S, CAS 387853-77-2
2-((2-Chlorobenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate
CAS 387853-77-2C15H14ClNO3S
[2-[(4-Fluorophenyl)methylamino]-2-oxoethyl] 5-methylthiophene-2-carboxylate chemical structure, C15H14FNO3S, CAS 479360-29-7
[2-[(4-Fluorophenyl)methylamino]-2-oxoethyl] 5-methylthiophene-2-carboxylate
CAS 479360-29-7C15H14FNO3S
{[(4-Methylphenyl)methyl]carbamoyl}methyl 5-methylthiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 1795032-77-7
{[(4-Methylphenyl)methyl]carbamoyl}methyl 5-methylthiophene-2-carboxylate
CAS 1795032-77-7C16H17NO3S
(Benzylcarbamoyl)methyl 5-methylthiophene-2-carboxylate chemical structure, C15H15NO3S, CAS 848584-99-6
(Benzylcarbamoyl)methyl 5-methylthiophene-2-carboxylate
CAS 848584-99-6C15H15NO3S
2-(Benzylamino)-2-oxoethyl 3-methylthiophene-2-carboxylate chemical structure, C15H15NO3S, CAS 438032-74-7
2-(Benzylamino)-2-oxoethyl 3-methylthiophene-2-carboxylate
CAS 438032-74-7C15H15NO3S
2-Oxo-2-((1-phenylethyl)amino)ethyl 3-methylthiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 479030-74-5
2-Oxo-2-((1-phenylethyl)amino)ethyl 3-methylthiophene-2-carboxylate
CAS 479030-74-5C16H17NO3S
[(1-Phenylethyl)carbamoyl]methyl 5-methylthiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 488754-75-2
[(1-Phenylethyl)carbamoyl]methyl 5-methylthiophene-2-carboxylate
CAS 488754-75-2C16H17NO3S
2-(Methyl(4-methylbenzyl)amino)-2-oxoethyl 4,5-dibromothiophene-2-carboxylate chemical structure, C16H15Br2NO3S, CAS 852934-82-8
2-(Methyl(4-methylbenzyl)amino)-2-oxoethyl 4,5-dibromothiophene-2-carboxylate
CAS 852934-82-8C16H15Br2NO3S
[2-[(3-Methoxyphenyl)methylamino]-2-oxoethyl] 5-chlorothiophene-2-carboxylate chemical structure, C15H14ClNO4S, CAS 877832-44-5
[2-[(3-Methoxyphenyl)methylamino]-2-oxoethyl] 5-chlorothiophene-2-carboxylate
CAS 877832-44-5C15H14ClNO4S
2-((3-Chlorobenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate chemical structure, C15H14ClNO3S, CAS 876152-89-5
2-((3-Chlorobenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate
CAS 876152-89-5C15H14ClNO3S
[2-[(3-Chlorophenyl)methylamino]-2-oxoethyl] 5-methylthiophene-2-carboxylate chemical structure, C15H14ClNO3S, CAS 876152-90-8
[2-[(3-Chlorophenyl)methylamino]-2-oxoethyl] 5-methylthiophene-2-carboxylate
CAS 876152-90-8C15H14ClNO3S
[2-[(3-Methoxyphenyl)methylamino]-2-oxoethyl] thiophene-2-carboxylate chemical structure, C15H15NO4S, CAS 1004458-53-0
[2-[(3-Methoxyphenyl)methylamino]-2-oxoethyl] thiophene-2-carboxylate
CAS 1004458-53-0C15H15NO4S
2-((3-Methoxybenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate chemical structure, C16H17NO4S, CAS 1004159-06-1
2-((3-Methoxybenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate
CAS 1004159-06-1C16H17NO4S
{[(3-Chlorophenyl)methyl]carbamoyl}methyl thiophene-2-carboxylate chemical structure, C14H12ClNO3S, CAS 876153-19-4
{[(3-Chlorophenyl)methyl]carbamoyl}methyl thiophene-2-carboxylate
CAS 876153-19-4C14H12ClNO3S
{[(2-Fluorophenyl)methyl]carbamoyl}methyl 3-methylthiophene-2-carboxylate chemical structure, C15H14FNO3S, CAS 1291853-77-4
{[(2-Fluorophenyl)methyl]carbamoyl}methyl 3-methylthiophene-2-carboxylate
CAS 1291853-77-4C15H14FNO3S
[2-[(2-Methylphenyl)methylamino]-2-oxoethyl] 5-methylthiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 1794897-59-8
[2-[(2-Methylphenyl)methylamino]-2-oxoethyl] 5-methylthiophene-2-carboxylate
CAS 1794897-59-8C16H17NO3S