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Murcko scaffold

Ring system with 2 rings and 18 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
22
With full pages
12
Scaffold SMILES

O=C(CNS(=O)(=O)c1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNS(=O)(=O)c1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

1-[2-(4-Methylbenzenesulfonamido)acetyl]pyrrolidine-2-carboxylic acid chemical structure, C14H18N2O5S, CAS 849440-93-3
1-[2-(4-Methylbenzenesulfonamido)acetyl]pyrrolidine-2-carboxylic acid
CAS 849440-93-3C14H18N2O5S
N,4-dimethyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]benzene-1-sulfonamide chemical structure, C14H20N2O3S, CAS 136787-48-9
N,4-dimethyl-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]benzene-1-sulfonamide
CAS 136787-48-9C14H20N2O3S
4-Chloro-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C13H17ClN2O3S, CAS 510716-59-3
4-Chloro-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 510716-59-3C13H17ClN2O3S
2,5-Dimethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C14H20N2O3S, CAS 690246-04-9
2,5-Dimethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 690246-04-9C14H20N2O3S
3-Methoxy-N-[2-oxo-2-(1-pyrrolidinyl)ethyl]benzenesulfonamide chemical structure, C13H18N2O4S, CAS 690245-96-6
3-Methoxy-N-[2-oxo-2-(1-pyrrolidinyl)ethyl]benzenesulfonamide
CAS 690245-96-6C13H18N2O4S
2,6-Dichloro-N-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide chemical structure, C12H14Cl2N2O3S, CAS 690647-27-9
2,6-Dichloro-N-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide
CAS 690647-27-9C12H14Cl2N2O3S
3-Chloro-4-fluoro-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C12H14ClFN2O3S, CAS 690647-41-7
3-Chloro-4-fluoro-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 690647-41-7C12H14ClFN2O3S
4-Methyl-N-(2-oxo-2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide chemical structure, C13H18N2O3S, CAS 122081-13-4
4-Methyl-N-(2-oxo-2-pyrrolidin-1-yl-ethyl)-benzenesulfonamide
CAS 122081-13-4C13H18N2O3S
4-Fluoro-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C13H17FN2O3S, CAS 675861-61-7
4-Fluoro-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 675861-61-7C13H17FN2O3S
N,2,4,6-tetramethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C16H24N2O3S, CAS 665017-56-1
N,2,4,6-tetramethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 665017-56-1C16H24N2O3S
2,5-Dimethoxy-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C15H22N2O5S, CAS 823825-50-9
2,5-Dimethoxy-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 823825-50-9C15H22N2O5S
4-tert-Butyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C16H24N2O3S, CAS 690644-60-1
4-tert-Butyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 690644-60-1C16H24N2O3S
2-Methoxy-N,5-dimethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C15H22N2O4S, CAS 710978-28-2
2-Methoxy-N,5-dimethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 710978-28-2C15H22N2O4S
3-Chloro-4-methoxy-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C14H19ClN2O4S, CAS 712319-78-3
3-Chloro-4-methoxy-N-methyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 712319-78-3C14H19ClN2O4S
N-Ethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C14H20N2O3S, CAS 838870-25-0
N-Ethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 838870-25-0C14H20N2O3S
2,5-Dichloro-N-ethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C14H18Cl2N2O3S, CAS 838897-93-1
2,5-Dichloro-N-ethyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 838897-93-1C14H18Cl2N2O3S
N-Ethyl-4-methoxy-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide chemical structure, C15H22N2O4S, CAS 838898-20-7
N-Ethyl-4-methoxy-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide
CAS 838898-20-7C15H22N2O4S
(R)-1-[2-(4-Methylbenzenesulfonamido)acetyl]pyrrolidine-2-carboxylic acid chemical structure, C14H18N2O5S, CAS 2185819-61-6
(R)-1-[2-(4-Methylbenzenesulfonamido)acetyl]pyrrolidine-2-carboxylic acid
CAS 2185819-61-6C14H18N2O5S
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid chemical structure, C14H18N2O5S, CAS 100723-71-5
(S)-1-(2-(4-Methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxylic acid
CAS 100723-71-5C14H18N2O5S
(2S)-1-[(2S)-2-[(2-Carboxyphenyl)sulfonylamino]propanoyl]pyrrolidine-2-carboxylic acid chemical structure, C15H18N2O7S, CAS 115084-54-3
(2S)-1-[(2S)-2-[(2-Carboxyphenyl)sulfonylamino]propanoyl]pyrrolidine-2-carboxylic acid
CAS 115084-54-3C15H18N2O7S
{1-[N-(Benzenesulfonyl)glycyl]pyrrolidin-2-yl}boronic acid chemical structure, C12H17BN2O5S, CAS 915283-83-9
{1-[N-(Benzenesulfonyl)glycyl]pyrrolidin-2-yl}boronic acid
CAS 915283-83-9C12H17BN2O5S
N-Ethyl-5-fluoro-2-methoxy-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]benzenesulfonamide chemical structure, C15H21FN2O4S, CAS 931258-09-2
N-Ethyl-5-fluoro-2-methoxy-N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]benzenesulfonamide
CAS 931258-09-2C15H21FN2O4S