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Murcko scaffold

5-Benzylidenebarbituric acid scaffold

133 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
133
With full pages
22
Scaffold SMILES

O=C1NC(=O)C(=Cc2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Benzylidenebarbituric acid page
Murcko scaffold O=C1NC(=O)C(=Cc2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 133 chemicals

5-(4-Methoxybenzylidene)barbituric acid chemical structure, C12H10N2O4, CAS 49546-71-6
5-(4-Methoxybenzylidene)barbituric acid
CAS 49546-71-6C12H10N2O4
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-((4-(dimethylamino)phenyl)methylene)- chemical structure, C13H13N3O3, CAS 1753-47-5
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-((4-(dimethylamino)phenyl)methylene)-
CAS 1753-47-5C13H13N3O3
5-((4-(Dimethylamino)phenyl)methylene)-1,3-dimethylbarbituric acid chemical structure, C15H17N3O3, CAS 57270-81-2
5-((4-(Dimethylamino)phenyl)methylene)-1,3-dimethylbarbituric acid
CAS 57270-81-2C15H17N3O3
5-{4-[Bis(2-chloroethyl)amino]benzylidene}pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C15H15Cl2N3O3, CAS 68961-21-7
5-{4-[Bis(2-chloroethyl)amino]benzylidene}pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 68961-21-7C15H15Cl2N3O3
5-Benzylidenebarbituric acid chemical structure, C11H8N2O3, CAS 27402-47-7
5-Benzylidenebarbituric acid
CAS 27402-47-7C11H8N2O3
5-({4-[Bis(2-chloroethyl)amino]-2-methylphenyl}methylidene)pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C16H17Cl2N3O3, CAS 84188-63-6
5-({4-[Bis(2-chloroethyl)amino]-2-methylphenyl}methylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 84188-63-6C16H17Cl2N3O3
5-(3-Bromo-benzylidene)-pyrimidine-2,4,6-trione chemical structure, C11H7BrN2O3, CAS 56504-53-1
5-(3-Bromo-benzylidene)-pyrimidine-2,4,6-trione
CAS 56504-53-1C11H7BrN2O3
5-(2-Bromobenzylidene)-2,4,6(1H,3H,5H)-pyrimidinetrione chemical structure, C11H7BrN2O3, CAS 57270-77-6
5-(2-Bromobenzylidene)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS 57270-77-6C11H7BrN2O3
5-(4-Bromobenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C11H7BrN2O3, CAS 49546-72-7
5-(4-Bromobenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 49546-72-7C11H7BrN2O3
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2-chlorophenyl)methylene]- chemical structure, C11H7ClN2O3, CAS 57270-78-7
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2-chlorophenyl)methylene]-
CAS 57270-78-7C11H7ClN2O3
5-[(3-Chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione chemical structure, C11H7ClN2O3, CAS 71732-11-1
5-[(3-Chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione
CAS 71732-11-1C11H7ClN2O3
5-(3-Nitrobenzylidene)hexahydropyrimidine-2,4,6-trione chemical structure, C11H7N3O5, CAS 27402-32-0
5-(3-Nitrobenzylidene)hexahydropyrimidine-2,4,6-trione
CAS 27402-32-0C11H7N3O5
5-(3-Methylbenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C12H10N2O3, CAS 93289-22-6
5-(3-Methylbenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 93289-22-6C12H10N2O3
5-[(2,3-Dimethoxyphenyl)methylidene]-1,3-diazinane-2,4,6-trione chemical structure, C13H12N2O5, CAS 93289-23-7
5-[(2,3-Dimethoxyphenyl)methylidene]-1,3-diazinane-2,4,6-trione
CAS 93289-23-7C13H12N2O5
RefChem:381799 chemical structure, C11H6Cl2N2O3, CAS 148119-31-7
RefChem:381799
CAS 148119-31-7C11H6Cl2N2O3
5-(5-Bromo-2-nitrobenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C11H6BrN3O5, CAS 26908-36-1
5-(5-Bromo-2-nitrobenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 26908-36-1C11H6BrN3O5
RefChem:357228 chemical structure, C11H7N3O5, CAS 26908-37-2
RefChem:357228
CAS 26908-37-2C11H7N3O5
5-(3,4-Dimethoxy-benzylidene)-pyrimidine-2,4,6-trione chemical structure, C13H12N2O5, CAS 66386-22-9
5-(3,4-Dimethoxy-benzylidene)-pyrimidine-2,4,6-trione
CAS 66386-22-9C13H12N2O5
5-[(4-Methoxyphenyl)methylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H14N2O4, CAS 57270-82-3
5-[(4-Methoxyphenyl)methylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 57270-82-3C14H14N2O4
1,3-Dimethyl-5-[(3-nitrophenyl)methylidene]-1,3-diazinane-2,4,6-trione chemical structure, C13H11N3O5, CAS 57270-90-3
1,3-Dimethyl-5-[(3-nitrophenyl)methylidene]-1,3-diazinane-2,4,6-trione
CAS 57270-90-3C13H11N3O5
1,3-Dimethyl-5-[[4-(methylamino)-3-nitrophenyl]methylidene]-1,3-diazinane-2,4,6-trione chemical structure, C14H14N4O5, CAS 62347-95-9
1,3-Dimethyl-5-[[4-(methylamino)-3-nitrophenyl]methylidene]-1,3-diazinane-2,4,6-trione
CAS 62347-95-9C14H14N4O5
5-(4-Chloro-benzylidene)-pyrimidine-2,4,6-trione chemical structure, C11H7ClN2O3, CAS 27402-31-9
5-(4-Chloro-benzylidene)-pyrimidine-2,4,6-trione
CAS 27402-31-9C11H7ClN2O3
5-(4-Nitrobenzylidene)barbituric acid chemical structure, C11H7N3O5, CAS 23536-26-7
5-(4-Nitrobenzylidene)barbituric acid
CAS 23536-26-7C11H7N3O5
5-[(4-Methylphenyl)methylidene]-1,3-diazinane-2,4,6-trione chemical structure, C12H10N2O3, CAS 56504-51-9
5-[(4-Methylphenyl)methylidene]-1,3-diazinane-2,4,6-trione
CAS 56504-51-9C12H10N2O3