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Murcko scaffold

Ring system with 3 rings and 22 atoms

436 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
436
With full pages
20
Scaffold SMILES

O=C(CSc1nccn1-c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nccn1-c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 436 chemicals

N-(4-Methoxyphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C18H17N3O2S, CAS 688335-23-1
N-(4-Methoxyphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-23-1C18H17N3O2S
N-(4-Fluorophenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide chemical structure, C17H14FN3OS, CAS 688335-24-2
N-(4-Fluorophenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide
CAS 688335-24-2C17H14FN3OS
N-(2-Fluorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C17H14FN3OS, CAS 688335-25-3
N-(2-Fluorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-25-3C17H14FN3OS
2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(p-tolyl)acetamide chemical structure, C18H17N3OS, CAS 688335-27-5
2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(p-tolyl)acetamide
CAS 688335-27-5C18H17N3OS
N-(3-Methylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide chemical structure, C18H17N3OS, CAS 688335-28-6
N-(3-Methylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide
CAS 688335-28-6C18H17N3OS
N-(2,3-Dimethylphenyl)-2-[(1-phenyl-1H-imidazol-2-yl)sulfanyl]acetamide chemical structure, C19H19N3OS, CAS 6242-76-8
N-(2,3-Dimethylphenyl)-2-[(1-phenyl-1H-imidazol-2-yl)sulfanyl]acetamide
CAS 6242-76-8C19H19N3OS
N-(2,5-Dimethylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide chemical structure, C19H19N3OS, CAS 688335-31-1
N-(2,5-Dimethylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide
CAS 688335-31-1C19H19N3OS
N-(2,4-Dimethylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide chemical structure, C19H19N3OS, CAS 688335-32-2
N-(2,4-Dimethylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide
CAS 688335-32-2C19H19N3OS
N-(3,5-Dimethylphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C19H19N3OS, CAS 688335-33-3
N-(3,5-Dimethylphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-33-3C19H19N3OS
N-(2,4-Difluorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C17H13F2N3OS, CAS 688335-37-7
N-(2,4-Difluorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-37-7C17H13F2N3OS
N-(3-Chlorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C17H14ClN3OS, CAS 688335-45-7
N-(3-Chlorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-45-7C17H14ClN3OS
N-(3-Fluorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C17H14FN3OS, CAS 688335-46-8
N-(3-Fluorophenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-46-8C17H14FN3OS
N-(4-Ethylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide chemical structure, C19H19N3OS, CAS 688335-47-9
N-(4-Ethylphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide
CAS 688335-47-9C19H19N3OS
N-(3-Methoxyphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C18H17N3O2S, CAS 688335-52-6
N-(3-Methoxyphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide
CAS 688335-52-6C18H17N3O2S
N-Phenyl-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C18H17N3OS, CAS 851130-98-8
N-Phenyl-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851130-98-8C18H17N3OS
N-(4-Fluorophenyl)-2-[1-(3-methylphenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C18H16FN3OS, CAS 851131-01-6
N-(4-Fluorophenyl)-2-[1-(3-methylphenyl)imidazol-2-yl]sulfanylacetamide
CAS 851131-01-6C18H16FN3OS
N-(2-Fluorophenyl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C18H16FN3OS, CAS 851131-02-7
N-(2-Fluorophenyl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851131-02-7C18H16FN3OS
N-(p-Tolyl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C19H19N3OS, CAS 851131-04-9
N-(p-Tolyl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851131-04-9C19H19N3OS
N-(3-Fluorophenyl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C18H16FN3OS, CAS 851131-25-4
N-(3-Fluorophenyl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 851131-25-4C18H16FN3OS
2-[1-(2,3-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-phenylacetamide chemical structure, C19H19N3OS, CAS 851131-45-8
2-[1-(2,3-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-phenylacetamide
CAS 851131-45-8C19H19N3OS
2-((1-(3,5-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-phenylacetamide chemical structure, C19H19N3OS, CAS 851131-86-7
2-((1-(3,5-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-phenylacetamide
CAS 851131-86-7C19H19N3OS
2-((1-(3-Methoxyphenyl)-1H-imidazol-2-yl)thio)-N-phenylacetamide chemical structure, C18H17N3O2S, CAS 688335-61-7
2-((1-(3-Methoxyphenyl)-1H-imidazol-2-yl)thio)-N-phenylacetamide
CAS 688335-61-7C18H17N3O2S
2-[1-(4-Methoxyphenyl)imidazol-2-yl]sulfanyl-N-phenylacetamide chemical structure, C18H17N3O2S, CAS 688335-83-3
2-[1-(4-Methoxyphenyl)imidazol-2-yl]sulfanyl-N-phenylacetamide
CAS 688335-83-3C18H17N3O2S
2-[1-(4-Fluorophenyl)imidazol-2-yl]sulfanyl-N-phenylacetamide chemical structure, C17H14FN3OS, CAS 688336-68-7
2-[1-(4-Fluorophenyl)imidazol-2-yl]sulfanyl-N-phenylacetamide
CAS 688336-68-7C17H14FN3OS