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Murcko scaffold

2-Oxabicyclo[2.2.2]octane scaffold

275 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
8
Chemicals
275
With full pages
67
Scaffold SMILES

C1CC2CCC1CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxabicyclo[2.2.2]octane page
Murcko scaffold C1CC2CCC1CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 275 of 275 chemicals

2-Chloro-1-(1-methyl-2-oxabicyclo[2.2.2]octan-4-yl)ethan-1-one chemical structure, C10H15ClO2, CAS 2573212-78-7
2-Chloro-1-(1-methyl-2-oxabicyclo[2.2.2]octan-4-yl)ethan-1-one
CAS 2573212-78-7C10H15ClO2
Ethyl 1-(Acetoxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylate chemical structure, C13H20O5, CAS 2918988-54-0
Ethyl 1-(Acetoxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylate
CAS 2918988-54-0C13H20O5
Ethyl 1-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylate chemical structure, C11H18O4, CAS 2918988-55-1
Ethyl 1-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylate
CAS 2918988-55-1C11H18O4
tert-Butyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C13H23NO3, CAS 2920141-86-0
tert-Butyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2920141-86-0C13H23NO3
Methyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C10H17NO3, CAS 2913268-49-0
Methyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2913268-49-0C10H17NO3
Methyl 4-formyl-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C10H14O4, CAS 2919954-93-9
Methyl 4-formyl-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2919954-93-9C10H14O4
4-[(2,2,2-Trifluoroacetamido)methyl]-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C11H14F3NO4, CAS 2920128-20-5
4-[(2,2,2-Trifluoroacetamido)methyl]-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2920128-20-5C11H14F3NO4
1-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid chemical structure, C9H14O4, CAS 2913268-08-1
1-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid
CAS 2913268-08-1C9H14O4
Methyl 4-(bromomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C10H15BrO3, CAS 2913278-84-7
Methyl 4-(bromomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2913278-84-7C10H15BrO3
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride chemical structure, C10H20ClNO, CAS 2901096-43-1
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride
CAS 2901096-43-1C10H20ClNO
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-4-amine chemical structure, C10H19NO, CAS 2901096-42-0
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-4-amine
CAS 2901096-42-0C10H19NO
Sodium 1-(hydroxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylate chemical structure, C9H13NaO4, CAS 2913268-09-2
Sodium 1-(hydroxymethyl)-2-oxabicyclo[2.2.2]octane-4-carboxylate
CAS 2913268-09-2C9H13NaO4
Methyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate hydrochloride chemical structure, C10H18ClNO3, CAS 2913268-50-3
Methyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate hydrochloride
CAS 2913268-50-3C10H18ClNO3
4-(Acetamidomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C11H17NO4, CAS 2920133-23-7
4-(Acetamidomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2920133-23-7C11H17NO4
Ethyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C11H19NO3, CAS 2920155-45-7
Ethyl 4-(aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2920155-45-7C11H19NO3
4-({[(Prop-2-en-1-yloxy)carbonyl]amino}methyl)-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C13H19NO5, CAS 2920158-61-6
4-({[(Prop-2-en-1-yloxy)carbonyl]amino}methyl)-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2920158-61-6C13H19NO5
1-(Iodomethyl)-2-oxabicyclo[2.2.2]octan-4-amine chemical structure, C8H14INO, CAS 2913404-96-1
1-(Iodomethyl)-2-oxabicyclo[2.2.2]octan-4-amine
CAS 2913404-96-1C8H14INO
tert-Butyl N-[1-(aminomethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate hydrochloride chemical structure, C13H25ClN2O3, CAS 2913241-40-2
tert-Butyl N-[1-(aminomethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate hydrochloride
CAS 2913241-40-2C13H25ClN2O3
tert-Butyl (1-(hydrazinecarbonyl)-2-oxabicyclo[2.2.2]octan-4-yl)carbamate chemical structure, C13H23N3O4, CAS 2411631-43-9
tert-Butyl (1-(hydrazinecarbonyl)-2-oxabicyclo[2.2.2]octan-4-yl)carbamate
CAS 2411631-43-9C13H23N3O4
4-(Aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylic acid hydrochloride chemical structure, C9H16ClNO3, CAS 2995285-85-1
4-(Aminomethyl)-2-oxabicyclo[2.2.2]octane-1-carboxylic acid hydrochloride
CAS 2995285-85-1C9H16ClNO3
Dimethyl 2-oxabicyclo[2.2.2]octane-1,4-dicarboxylate chemical structure, C11H16O5, CAS 2940957-95-7
Dimethyl 2-oxabicyclo[2.2.2]octane-1,4-dicarboxylate
CAS 2940957-95-7C11H16O5
1-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride chemical structure, C8H13ClF3NO, CAS 3031792-00-1
1-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride
CAS 3031792-00-1C8H13ClF3NO
Methyl 4-carbamoyl-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C10H15NO4, CAS 3057544-36-9
Methyl 4-carbamoyl-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 3057544-36-9C10H15NO4
Methyl 2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C9H14O3, CAS 2932441-16-0
Methyl 2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2932441-16-0C9H14O3