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Murcko scaffold

2-Oxabicyclo[2.2.2]octane scaffold

275 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
8
Chemicals
275
With full pages
67
Scaffold SMILES

C1CC2CCC1CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxabicyclo[2.2.2]octane page
Murcko scaffold C1CC2CCC1CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 275 chemicals

Methyl 4-cyano-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C10H13NO3, CAS 2375195-10-9
Methyl 4-cyano-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2375195-10-9C10H13NO3
Methyl 4-bromo-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C9H13BrO3, CAS 2375194-01-5
Methyl 4-bromo-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2375194-01-5C9H13BrO3
4-Bromo-2-oxabicyclo[2.2.2]octane-1-carbonitrile chemical structure, C8H10BrNO, CAS 2375196-06-6
4-Bromo-2-oxabicyclo[2.2.2]octane-1-carbonitrile
CAS 2375196-06-6C8H10BrNO
4-[(tert-Butoxycarbonylamino)methyl]-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C14H23NO5, CAS 2375195-92-7
4-[(tert-Butoxycarbonylamino)methyl]-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2375195-92-7C14H23NO5
4-(Methoxycarbonyl)-2-oxabicyclo(2.2.2)octane-1-carboxylic acid chemical structure, C10H14O5, CAS 2375195-27-8
4-(Methoxycarbonyl)-2-oxabicyclo(2.2.2)octane-1-carboxylic acid
CAS 2375195-27-8C10H14O5
3-Methyl-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C9H14O3, CAS 2445784-32-5
3-Methyl-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2445784-32-5C9H14O3
1-(Methoxymethyl)-2-oxabicyclo(2.2.2)octane-4-carboxylic acid chemical structure, C10H16O4, CAS 2490430-33-4
1-(Methoxymethyl)-2-oxabicyclo(2.2.2)octane-4-carboxylic acid
CAS 2490430-33-4C10H16O4
1-(Methoxymethyl)-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride chemical structure, C9H18ClNO2, CAS 2490432-61-4
1-(Methoxymethyl)-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride
CAS 2490432-61-4C9H18ClNO2
1-(Methoxymethyl)-2-oxabicyclo[2.2.2]octan-4-amine chemical structure, C9H17NO2, CAS 2490404-56-1
1-(Methoxymethyl)-2-oxabicyclo[2.2.2]octan-4-amine
CAS 2490404-56-1C9H17NO2
1-Ethyl-2-oxabicyclo[2.2.2]octane-4-carboxylic acid chemical structure, C10H16O3, CAS 2460750-73-4
1-Ethyl-2-oxabicyclo[2.2.2]octane-4-carboxylic acid
CAS 2460750-73-4C10H16O3
(4-Amino-2-oxabicyclo[2.2.2]octan-1-yl)methanol hydrochloride chemical structure, C8H16ClNO2, CAS 2361122-53-2
(4-Amino-2-oxabicyclo[2.2.2]octan-1-yl)methanol hydrochloride
CAS 2361122-53-2C8H16ClNO2
2-Bromo-1-(1-methyl-2-oxabicyclo(2.2.2)octan-4-yl)ethan-1-one chemical structure, C10H15BrO2, CAS 2573214-04-5
2-Bromo-1-(1-methyl-2-oxabicyclo(2.2.2)octan-4-yl)ethan-1-one
CAS 2573214-04-5C10H15BrO2
1-Ethyl-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride chemical structure, C9H18ClNO, CAS 2470439-06-4
1-Ethyl-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride
CAS 2470439-06-4C9H18ClNO
1-Ethyl-2-oxabicyclo[2.2.2]octan-4-amine chemical structure, C9H17NO, CAS 2470436-99-6
1-Ethyl-2-oxabicyclo[2.2.2]octan-4-amine
CAS 2470436-99-6C9H17NO
4-Ethynyl-2-oxabicyclo[2.2.2]octane chemical structure, C9H12O, CAS 2460749-03-3
4-Ethynyl-2-oxabicyclo[2.2.2]octane
CAS 2460749-03-3C9H12O
1-(3,3-Dimethyl-2-oxabicyclo(2.2.2)octan-1-yl)methanamine hydrochloride chemical structure, C10H20ClNO, CAS 2503206-58-2
1-(3,3-Dimethyl-2-oxabicyclo(2.2.2)octan-1-yl)methanamine hydrochloride
CAS 2503206-58-2C10H20ClNO
1-{3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-1-yl}methanamine chemical structure, C10H19NO, CAS 2503206-51-5
1-{3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-1-yl}methanamine
CAS 2503206-51-5C10H19NO
Methyl 1-formyl-2-oxabicyclo[2.2.2]octane-4-carboxylate chemical structure, C10H14O4, CAS 2387596-68-9
Methyl 1-formyl-2-oxabicyclo[2.2.2]octane-4-carboxylate
CAS 2387596-68-9C10H14O4
[3-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octan-3-yl]methanol chemical structure, C9H13F3O2, CAS 2613382-52-6
[3-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octan-3-yl]methanol
CAS 2613382-52-6C9H13F3O2
3-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octane-3-carboxylicacid chemical structure, C9H11F3O3, CAS 2613384-02-2
3-(Trifluoromethyl)-2-oxabicyclo[2.2.2]octane-3-carboxylicacid
CAS 2613384-02-2C9H11F3O3
tert-Butyl 4-amino-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C12H21NO3, CAS 2580252-21-5
tert-Butyl 4-amino-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2580252-21-5C12H21NO3
2-Bromo-1-(4-methyl-2-oxabicyclo[2.2.2]octan-1-yl)ethanone chemical structure, C10H15BrO2, CAS 2648410-64-2
2-Bromo-1-(4-methyl-2-oxabicyclo[2.2.2]octan-1-yl)ethanone
CAS 2648410-64-2C10H15BrO2
4-Methyl-2-oxabicyclo[2.2.2]octan-1-amine chemical structure, C8H15NO, CAS 2940945-02-6
4-Methyl-2-oxabicyclo[2.2.2]octan-1-amine
CAS 2940945-02-6C8H15NO
{1-Methyl-2-oxabicyclo[2.2.2]octan-4-yl}methanesulfonamide chemical structure, C9H17NO3S, CAS 2137101-39-2
{1-Methyl-2-oxabicyclo[2.2.2]octan-4-yl}methanesulfonamide
CAS 2137101-39-2C9H17NO3S