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Murcko scaffold

Isoxazole scaffold

5,682 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
5,682
With full pages
801
Scaffold SMILES

c1cnoc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isoxazole page
Murcko scaffold c1cnoc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 5,682 chemicals

Ethyl 5-amino-3-(2-hydroxyethoxy)-4-isoxazolecarboxylate chemical structure, C8H12N2O5, CAS 446276-12-6
Ethyl 5-amino-3-(2-hydroxyethoxy)-4-isoxazolecarboxylate
CAS 446276-12-6C8H12N2O5
Dimethyl 2-(5-isoxazolyl)succinate chemical structure, C9H11NO5, CAS 477858-68-7
Dimethyl 2-(5-isoxazolyl)succinate
CAS 477858-68-7C9H11NO5
Ethyl 3-[2-(acetyloxy)ethoxy]-5-amino-4-isoxazolecarboxylate chemical structure, C10H14N2O6, CAS 303997-34-4
Ethyl 3-[2-(acetyloxy)ethoxy]-5-amino-4-isoxazolecarboxylate
CAS 303997-34-4C10H14N2O6
(5-Methyl-1,2-oxazol-3-yl)thiourea chemical structure, C5H7N3OS, CAS 943116-90-3
(5-Methyl-1,2-oxazol-3-yl)thiourea
CAS 943116-90-3C5H7N3OS
4-Bromo-5-methyl-1,2-oxazol-3-amine chemical structure, C4H5BrN2O, CAS 5819-40-9
4-Bromo-5-methyl-1,2-oxazol-3-amine
CAS 5819-40-9C4H5BrN2O
3-Methyl-5-(trifluoromethyl)isoxazole-4-carbonyl chloride chemical structure, C6H3ClF3NO2, CAS 517920-77-3
3-Methyl-5-(trifluoromethyl)isoxazole-4-carbonyl chloride
CAS 517920-77-3C6H3ClF3NO2
3-Methyl-5-(trifluoromethyl)-1,2-oxazole-4-carboxylic acid chemical structure, C6H4F3NO3, CAS 193952-09-9
3-Methyl-5-(trifluoromethyl)-1,2-oxazole-4-carboxylic acid
CAS 193952-09-9C6H4F3NO3
3,5-Dimethylisoxazole-4-carbonitrile chemical structure, C6H6N2O, CAS 31301-46-9
3,5-Dimethylisoxazole-4-carbonitrile
CAS 31301-46-9C6H6N2O
5-Methyl-1,2-oxazole-4-sulfonyl chloride chemical structure, C4H4ClNO3S, CAS 321309-26-6
5-Methyl-1,2-oxazole-4-sulfonyl chloride
CAS 321309-26-6C4H4ClNO3S
3,5-Dimethyl-4-isoxazolyl isothiocyanate chemical structure, C6H6N2OS, CAS 321309-27-7
3,5-Dimethyl-4-isoxazolyl isothiocyanate
CAS 321309-27-7C6H6N2OS
3-Isothiocyanato-5-methyl-1,2-oxazole chemical structure, C5H4N2OS, CAS 321309-33-5
3-Isothiocyanato-5-methyl-1,2-oxazole
CAS 321309-33-5C5H4N2OS
3-(Bromomethyl)-5-methylisoxazole chemical structure, C5H6BrNO, CAS 130628-75-0
3-(Bromomethyl)-5-methylisoxazole
CAS 130628-75-0C5H6BrNO
1-(5-Methyl-1,2-oxazol-3-yl)methanamine chemical structure, C5H8N2O, CAS 154016-48-5
1-(5-Methyl-1,2-oxazol-3-yl)methanamine
CAS 154016-48-5C5H8N2O
6-Chloro-N-(5-methyl-1,2-oxazol-3-yl)hexanamide chemical structure, C10H15ClN2O2, CAS 647825-17-0
6-Chloro-N-(5-methyl-1,2-oxazol-3-yl)hexanamide
CAS 647825-17-0C10H15ClN2O2
3-Bromo-N-(5-methylisoxazol-3-yl)propanamide chemical structure, C7H9BrN2O2, CAS 349442-99-5
3-Bromo-N-(5-methylisoxazol-3-yl)propanamide
CAS 349442-99-5C7H9BrN2O2
2-Chloro-N-(3-methyl-1,2-oxazol-5-yl)acetamide chemical structure, C6H7ClN2O2, CAS 69000-39-1
2-Chloro-N-(3-methyl-1,2-oxazol-5-yl)acetamide
CAS 69000-39-1C6H7ClN2O2
N-(4-Bromo-3-methyl-1,2-oxazol-5-yl)-2-chloroacetamide chemical structure, C6H6BrClN2O2, CAS 649701-21-3
N-(4-Bromo-3-methyl-1,2-oxazol-5-yl)-2-chloroacetamide
CAS 649701-21-3C6H6BrClN2O2
2-Chloro-N-(3-methyl-4-nitro-1,2-oxazol-5-yl)acetamide chemical structure, C6H6ClN3O4, CAS 649701-59-7
2-Chloro-N-(3-methyl-4-nitro-1,2-oxazol-5-yl)acetamide
CAS 649701-59-7C6H6ClN3O4
Ethyl 3-methyl-5-(trifluoromethyl)-1,2-oxazole-4-carboxylate chemical structure, C8H8F3NO3, CAS 256471-34-8
Ethyl 3-methyl-5-(trifluoromethyl)-1,2-oxazole-4-carboxylate
CAS 256471-34-8C8H8F3NO3
5-Methyl-1,2-oxazole-3-carbaldehyde chemical structure, C5H5NO2, CAS 62254-74-4
5-Methyl-1,2-oxazole-3-carbaldehyde
CAS 62254-74-4C5H5NO2
4-Iodo-5-methylisoxazole chemical structure, C4H4INO, CAS 7064-38-2
4-Iodo-5-methylisoxazole
CAS 7064-38-2C4H4INO
3-Aminoisoxazole-4-carbonitrile chemical structure, C4H3N3O, CAS 258518-65-9
3-Aminoisoxazole-4-carbonitrile
CAS 258518-65-9C4H3N3O
N,N-Dimethyl-N'-(5-methyl-1,2-oxazol-3-yl)methanimidamide chemical structure, C7H11N3O, CAS 134540-15-1
N,N-Dimethyl-N'-(5-methyl-1,2-oxazol-3-yl)methanimidamide
CAS 134540-15-1C7H11N3O
Methyl 4-acetyl-5-methyl-1,2-oxazole-3-carboxylate chemical structure, C8H9NO4, CAS 104149-61-3
Methyl 4-acetyl-5-methyl-1,2-oxazole-3-carboxylate
CAS 104149-61-3C8H9NO4