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Murcko scaffold

5-(1H-Pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol scaffold

32 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 32
With full pages: 3

Scaffold SMILES

S=c1[nH]nc(-c2cc[nH]n2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-(1H-Pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol page

Murcko scaffold S=c1[nH]nc(-c2cc[nH]n2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C8H11N5S, CAS 957299-16-0

5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol

CAS 957299-16-0C₈H₁₁N₅S

3-(4-Chloro-1,5-dimethylpyrazol-3-yl)-4-methyl-1H-1,2,4-triazole-5-thione chemical structure, C8H10ClN5S, CAS 512816-38-5

3-(4-Chloro-1,5-dimethylpyrazol-3-yl)-4-methyl-1H-1,2,4-triazole-5-thione

CAS 512816-38-5C₈H₁₀ClN₅S

5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol chemical structure, C9H13N5S, CAS 494747-28-3

5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol

CAS 494747-28-3C₉H₁₃N₅S

5-(4-Chloro-1,3-dimethyl-1H-pyrazol-5-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol chemical structure, C9H12ClN5S, CAS 512811-35-7

5-(4-Chloro-1,3-dimethyl-1H-pyrazol-5-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol

CAS 512811-35-7C₉H₁₂ClN₅S

3-(4-Chloro-2,5-dimethylpyrazol-3-yl)-4-methyl-1H-1,2,4-triazole-5-thione chemical structure, C8H10ClN5S, CAS 512817-43-5

3-(4-Chloro-2,5-dimethylpyrazol-3-yl)-4-methyl-1H-1,2,4-triazole-5-thione

CAS 512817-43-5C₈H₁₀ClN₅S

5-(3-Ethyl-1-methyl-1H-pyrazol-5-yl)-1H-1,2,4-triazole-3(2H)-thione chemical structure, C8H11N5S, CAS 294846-24-5

5-(3-Ethyl-1-methyl-1H-pyrazol-5-yl)-1H-1,2,4-triazole-3(2H)-thione

CAS 294846-24-5C₈H₁₁N₅S

4-Butyl-3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-1H-1,2,4-triazole-5-thione chemical structure, C11H16ClN5S, CAS 494747-27-2

4-Butyl-3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-1H-1,2,4-triazole-5-thione

CAS 494747-27-2C₁₁H₁₆ClN₅S

5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-isobutyl-4H-1,2,4-triazole-3-thiol chemical structure, C11H17N5S, CAS 512810-96-7

5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-isobutyl-4H-1,2,4-triazole-3-thiol

CAS 512810-96-7C₁₁H₁₇N₅S

5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol chemical structure, C9H13N5S, CAS 512811-93-7

5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol

CAS 512811-93-7C₉H₁₃N₅S

3-(4-Chloro-1-methylpyrazol-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione chemical structure, C10H14ClN5S, CAS 494791-07-0

3-(4-Chloro-1-methylpyrazol-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione

CAS 494791-07-0C₁₀H₁₄ClN₅S

3-(4-Chloro-1,5-dimethylpyrazol-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione chemical structure, C11H16ClN5S, CAS 494747-53-4

3-(4-Chloro-1,5-dimethylpyrazol-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione

CAS 494747-53-4C₁₁H₁₆ClN₅S

4-Butyl-3-(2,5-dimethylpyrazol-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C11H17N5S, CAS 512810-70-7

4-Butyl-3-(2,5-dimethylpyrazol-3-yl)-1H-1,2,4-triazole-5-thione

CAS 512810-70-7C₁₁H₁₇N₅S

3-(4-Chloro-2,5-dimethylpyrazol-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione chemical structure, C11H16ClN5S, CAS 494790-81-7

3-(4-Chloro-2,5-dimethylpyrazol-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione

CAS 494790-81-7C₁₁H₁₆ClN₅S

4-Methyl-5-(1-methyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C7H9N5S, CAS 914096-56-3

4-Methyl-5-(1-methyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol

CAS 914096-56-3C₇H₉N₅S

4-Methyl-5-(1-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C7H9N5S, CAS 1004020-58-9

4-Methyl-5-(1-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 1004020-58-9C₇H₉N₅S

5-(5-Mercapto-4-methyl-4H-1,2,4-triazol-3-yl)-1-methyl-1H-pyrazole-3-carboxylic acid chemical structure, C8H9N5O2S, CAS 1005580-13-1

5-(5-Mercapto-4-methyl-4H-1,2,4-triazol-3-yl)-1-methyl-1H-pyrazole-3-carboxylic acid

CAS 1005580-13-1C₈H₉N₅O₂S

2-[3-(1H-Pyrazol-5-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]propanoic acid chemical structure, C8H9N5O2S, CAS 879449-62-4

2-[3-(1H-Pyrazol-5-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]propanoic acid

CAS 879449-62-4C₈H₉N₅O₂S

4-Butyl-5-(4-chloro-1-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C10H14ClN5S, CAS 512813-82-0

4-Butyl-5-(4-chloro-1-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 512813-82-0C₁₀H₁₄ClN₅S

4-Butyl-5-(4-chloro-1,3-dimethyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H16ClN5S, CAS 494790-66-8

4-Butyl-5-(4-chloro-1,3-dimethyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol

CAS 494790-66-8C₁₁H₁₆ClN₅S

5-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)-4-isobutyl-4H-1,2,4-triazole-3-thiol chemical structure, C11H16BrN5S, CAS 494747-71-6

5-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)-4-isobutyl-4H-1,2,4-triazole-3-thiol

CAS 494747-71-6C₁₁H₁₆BrN₅S

4-Methyl-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C8H8F3N5S, CAS 1001567-71-0

4-Methyl-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol

CAS 1001567-71-0C₈H₈F₃N₅S

4-Ethyl-5-(1-ethyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C9H13N5S, CAS 1001559-22-3

4-Ethyl-5-(1-ethyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 1001559-22-3C₉H₁₃N₅S

4-Ethyl-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C9H10F3N5S, CAS 1001559-40-5

4-Ethyl-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol

CAS 1001559-40-5C₉H₁₀F₃N₅S

4-Ethyl-5-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C9H10F3N5S, CAS 1001756-37-1

4-Ethyl-5-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 1001756-37-1C₉H₁₀F₃N₅S