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Murcko scaffold

Saccharin scaffold

264 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
264
With full pages
67
Scaffold SMILES

O=C1NS(=O)(=O)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Saccharin page
Murcko scaffold O=C1NS(=O)(=O)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 264 chemicals

Saccharin chemical structure, C7H5NO3S, CAS 81-07-2
Saccharin
CAS 81-07-2C7H5NO3S
2-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide chemical structure, C8H7NO3S, CAS 15448-99-4
2-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide
CAS 15448-99-4C8H7NO3S
5-Aminosaccharin chemical structure, C7H6N2O3S, CAS 22094-61-7
5-Aminosaccharin
CAS 22094-61-7C7H6N2O3S
6-Aminosaccharin chemical structure, C7H6N2O3S, CAS 22094-62-8
6-Aminosaccharin
CAS 22094-62-8C7H6N2O3S
5-Chlorosaccharin chemical structure, C7H4ClNO3S, CAS 29083-16-7
5-Chlorosaccharin
CAS 29083-16-7C7H4ClNO3S
N-Bromosaccharin chemical structure, C7H4BrNO3S, CAS 35812-01-2
N-Bromosaccharin
CAS 35812-01-2C7H4BrNO3S
2-(Hydroxymethyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide chemical structure, C8H7NO4S, CAS 13947-20-1
2-(Hydroxymethyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide
CAS 13947-20-1C8H7NO4S
2-(2-Hydroxyethyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide chemical structure, C9H9NO4S, CAS 6343-81-3
2-(2-Hydroxyethyl)-1,2-benzisothiazol-3(2H)-one 1,1-dioxide
CAS 6343-81-3C9H9NO4S
Saccharin N-(2-acetic acid methyl ester) chemical structure, C10H9NO5S, CAS 6639-62-9
Saccharin N-(2-acetic acid methyl ester)
CAS 6639-62-9C10H9NO5S
2-Allyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide chemical structure, C10H9NO3S, CAS 41335-56-2
2-Allyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide
CAS 41335-56-2C10H9NO3S
6-Nitrosaccharin chemical structure, C7H4N2O5S, CAS 22952-24-5
6-Nitrosaccharin
CAS 22952-24-5C7H4N2O5S
6-Chlorosaccharin chemical structure, C7H4ClNO3S, CAS 46149-10-4
6-Chlorosaccharin
CAS 46149-10-4C7H4ClNO3S
1,2-Benzisothiazole-4-sulfonic acid, 2,3-dihydro-3-oxo-, 1,1-dioxide chemical structure, C7H5NO6S2, CAS 68334-66-7
1,2-Benzisothiazole-4-sulfonic acid, 2,3-dihydro-3-oxo-, 1,1-dioxide
CAS 68334-66-7C7H5NO6S2
2-(2-Methylsulfanylethyl)-1,1-dioxo-1,2-benzothiazol-3-one chemical structure, C10H11NO3S2, CAS 125698-32-0
2-(2-Methylsulfanylethyl)-1,1-dioxo-1,2-benzothiazol-3-one
CAS 125698-32-0C10H11NO3S2
Ethyl 3-oxo-1,2-benzothiazole-2(3H)-carboxylate 1,1-dioxide chemical structure, C10H9NO5S, CAS 6971-09-1
Ethyl 3-oxo-1,2-benzothiazole-2(3H)-carboxylate 1,1-dioxide
CAS 6971-09-1C10H9NO5S
N,N-Diethyl-1,1,3-trioxo-1,3-dihydro-2H-1lambda~6~,2-benzothiazole-2-carboxamide chemical structure, C12H14N2O4S, CAS 5443-42-5
N,N-Diethyl-1,1,3-trioxo-1,3-dihydro-2H-1lambda~6~,2-benzothiazole-2-carboxamide
CAS 5443-42-5C12H14N2O4S
1,2-Benzisothiazol-3(2H)-one, 2-ethyl-, 1,1-dioxide chemical structure, C9H9NO3S, CAS 18712-20-4
1,2-Benzisothiazol-3(2H)-one, 2-ethyl-, 1,1-dioxide
CAS 18712-20-4C9H9NO3S
1,1-Dioxo-2-propan-2-yl-1,2-benzothiazol-3-one chemical structure, C10H11NO3S, CAS 91950-12-8
1,1-Dioxo-2-propan-2-yl-1,2-benzothiazol-3-one
CAS 91950-12-8C10H11NO3S
2-Dodecyl-1H-1lambda~6~,2-benzothiazole-1,1,3(2H)-trione chemical structure, C19H29NO3S, CAS 90012-37-6
2-Dodecyl-1H-1lambda~6~,2-benzothiazole-1,1,3(2H)-trione
CAS 90012-37-6C19H29NO3S
(1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetonitrile chemical structure, C9H6N2O3S, CAS 52188-12-2
(1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetonitrile
CAS 52188-12-2C9H6N2O3S
4-(1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)butanenitrile chemical structure, C11H10N2O3S, CAS 10313-98-1
4-(1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)butanenitrile
CAS 10313-98-1C11H10N2O3S
2-Hexyl-1H-1lambda~6~,2-benzothiazole-1,1,3(2H)-trione chemical structure, C13H17NO3S, CAS 90012-36-5
2-Hexyl-1H-1lambda~6~,2-benzothiazole-1,1,3(2H)-trione
CAS 90012-36-5C13H17NO3S
2-Octyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide chemical structure, C15H21NO3S, CAS 40523-10-2
2-Octyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide
CAS 40523-10-2C15H21NO3S
Ethyl 2-(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)butanoate chemical structure, C13H15NO5S, CAS 6639-65-2
Ethyl 2-(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)butanoate
CAS 6639-65-2C13H15NO5S