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Murcko scaffold

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole scaffold

272 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
272
With full pages
23
Scaffold SMILES

c1n[nH]c2c1CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole page
Murcko scaffold c1n[nH]c2c1CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 272 of 272 chemicals

tert-Butyl 1,4-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carboxylate chemical structure, C12H19N3O2, CAS 2749956-17-8
tert-Butyl 1,4-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carboxylate
CAS 2749956-17-8C12H19N3O2
5-Acetyl-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C9H11N3O3, CAS 2913405-33-9
5-Acetyl-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2913405-33-9C9H11N3O3
2-Amino-1-{1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}ethan-1-one dihydrochloride chemical structure, C7H12Cl2N4O, CAS 2913280-69-8
2-Amino-1-{1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}ethan-1-one dihydrochloride
CAS 2913280-69-8C7H12Cl2N4O
2-Methyl-5-[(prop-2-en-1-yloxy)carbonyl]-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C11H13N3O4, CAS 2913414-62-5
2-Methyl-5-[(prop-2-en-1-yloxy)carbonyl]-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2913414-62-5C11H13N3O4
3-Iodo-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole chemical structure, C6H8IN3, CAS 2920161-74-4
3-Iodo-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole
CAS 2920161-74-4C6H8IN3
2-Methyl-5-(2,2,2-trifluoroacetyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C9H8F3N3O3, CAS 2913410-27-0
2-Methyl-5-(2,2,2-trifluoroacetyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2913410-27-0C9H8F3N3O3
5-[(Prop-2-en-1-yloxy)carbonyl]-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C10H11N3O4, CAS 2913415-56-0
5-[(Prop-2-en-1-yloxy)carbonyl]-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2913415-56-0C10H11N3O4
tert-Butyl 2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate chemical structure, C11H17N3O2, CAS 2818202-31-0
tert-Butyl 2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate
CAS 2818202-31-0C11H17N3O2
5-(tert-Butyl) 3-methyl 2-methyl-2,6-dihydropyrrolo[3,4-c]pyrazole-3,5(4H)-dicarboxylate chemical structure, C13H19N3O4, CAS 2110454-39-0
5-(tert-Butyl) 3-methyl 2-methyl-2,6-dihydropyrrolo[3,4-c]pyrazole-3,5(4H)-dicarboxylate
CAS 2110454-39-0C13H19N3O4
Ethyl (R)-1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole-4-carboxylate Hydrochloride chemical structure, C8H12ClN3O2, CAS 1827680-56-7
Ethyl (R)-1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole-4-carboxylate Hydrochloride
CAS 1827680-56-7C8H12ClN3O2
5-(1,1-Dimethylethyl) 4-methyl 2,6-dihydro-2-methylpyrrolo[3,4-c]pyrazole-4,5(4H)-dicarboxylate chemical structure, C13H19N3O4, CAS 2384816-47-9
5-(1,1-Dimethylethyl) 4-methyl 2,6-dihydro-2-methylpyrrolo[3,4-c]pyrazole-4,5(4H)-dicarboxylate
CAS 2384816-47-9C13H19N3O4
Pyrrolo[3,4-c]pyrazole-4-carboxylic acid, 2,4,5,6-tetrahydro-, hydrochloride chemical structure, C6H8ClN3O2, CAS 2978522-99-3
Pyrrolo[3,4-c]pyrazole-4-carboxylic acid, 2,4,5,6-tetrahydro-, hydrochloride
CAS 2978522-99-3C6H8ClN3O2
5-tert-Butoxycarbonyl-1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-6-carboxylic acid chemical structure, C12H17N3O4, CAS 2387240-75-5
5-tert-Butoxycarbonyl-1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-6-carboxylic acid
CAS 2387240-75-5C12H17N3O4
5-(tert-Butyl) 4-methyl 1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-4,5(1H)-dicarboxylate chemical structure, C13H19N3O4, CAS 1822542-86-8
5-(tert-Butyl) 4-methyl 1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-4,5(1H)-dicarboxylate
CAS 1822542-86-8C13H19N3O4
5-(tert-Butoxycarbonyl)-6-ethyl-1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C14H21N3O4, CAS 2792143-86-1
5-(tert-Butoxycarbonyl)-6-ethyl-1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2792143-86-1C14H21N3O4
tert-Butyl 3-iodo-6-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate chemical structure, C11H16IN3O2, CAS 2792143-80-5
tert-Butyl 3-iodo-6-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate
CAS 2792143-80-5C11H16IN3O2
5-(tert-Butoxycarbonyl)-6-(((tert-butyldimethylsilyl)oxy)methyl)-1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C19H33N3O5Si, CAS 2792143-93-0
5-(tert-Butoxycarbonyl)-6-(((tert-butyldimethylsilyl)oxy)methyl)-1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2792143-93-0C19H33N3O5Si
(S)-5-(tert-Butoxycarbonyl)-6-isopropyl-1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C15H23N3O4, CAS 2792143-75-8
(S)-5-(tert-Butoxycarbonyl)-6-isopropyl-1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2792143-75-8C15H23N3O4
(R)-5-(tert-Butoxycarbonyl)-1,4-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C13H19N3O4, CAS 2792144-07-9
(R)-5-(tert-Butoxycarbonyl)-1,4-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2792144-07-9C13H19N3O4
5-(tert-Butyl) 3-ethyl 1-methyl-4,6-dihydropyrrolo[3,4-C]pyrazole-3,5(1H)-dicarboxylate chemical structure, C14H21N3O4, CAS 2108115-63-3
5-(tert-Butyl) 3-ethyl 1-methyl-4,6-dihydropyrrolo[3,4-C]pyrazole-3,5(1H)-dicarboxylate
CAS 2108115-63-3C14H21N3O4
Ethyl 1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole-3-carboxylate hydrochloride chemical structure, C9H14ClN3O2, CAS 2792143-28-1
Ethyl 1-methyl-1,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole-3-carboxylate hydrochloride
CAS 2792143-28-1C9H14ClN3O2
Trimethyl-[2-[(3-methyl-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)methoxy]ethyl]silane chemical structure, C12H23N3OSi, CAS 2767197-48-6
Trimethyl-[2-[(3-methyl-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazol-2-yl)methoxy]ethyl]silane
CAS 2767197-48-6C12H23N3OSi
tert-Butyl (4R)-4-methyl-4,6-dihydro-2H-pyrrolo[3,4-c]pyrazole-5-carboxylate chemical structure, C11H17N3O2, CAS 2716884-49-8
tert-Butyl (4R)-4-methyl-4,6-dihydro-2H-pyrrolo[3,4-c]pyrazole-5-carboxylate
CAS 2716884-49-8C11H17N3O2
(4S)-4-Methyl-1,4,5,6-tetrahydropyrrolo[3,4-d]pyrazole chemical structure, C6H9N3
(4S)-4-Methyl-1,4,5,6-tetrahydropyrrolo[3,4-d]pyrazole
C6H9N3