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Murcko scaffold

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole scaffold

272 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
272
With full pages
23
Scaffold SMILES

c1n[nH]c2c1CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole page
Murcko scaffold c1n[nH]c2c1CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 272 chemicals

Methyl 6,6-dimethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate chemical structure, C9H13N3O2, CAS 2287310-18-1
Methyl 6,6-dimethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate
CAS 2287310-18-1C9H13N3O2
Ethyl 2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate chemical structure, C9H13N3O2, CAS 2287261-07-6
Ethyl 2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate
CAS 2287261-07-6C9H13N3O2
6,6-Dimethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-amine dihydrochloride chemical structure, C7H14Cl2N4, CAS 2225154-22-1
6,6-Dimethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-amine dihydrochloride
CAS 2225154-22-1C7H14Cl2N4
1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazol-3-amine dihydrochloride chemical structure, C5H10Cl2N4, CAS 2193067-04-6
1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazol-3-amine dihydrochloride
CAS 2193067-04-6C5H10Cl2N4
2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazole-4-carboxamide dihydrochloride chemical structure, C6H10Cl2N4O, CAS 2225142-27-6
2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazole-4-carboxamide dihydrochloride
CAS 2225142-27-6C6H10Cl2N4O
2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazole-4-carboxamide chemical structure, C6H8N4O, CAS 2225137-22-2
2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazole-4-carboxamide
CAS 2225137-22-2C6H8N4O
5-((tert-Butoxy)carbonyl)-6,6-dimethyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazole-3-carboxylic acid chemical structure, C13H19N3O4, CAS 2243511-99-9
5-((tert-Butoxy)carbonyl)-6,6-dimethyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazole-3-carboxylic acid
CAS 2243511-99-9C13H19N3O4
2-Chloro-1-{1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}ethan-1-one hydrochloride chemical structure, C7H9Cl2N3O, CAS 2249078-44-0
2-Chloro-1-{1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}ethan-1-one hydrochloride
CAS 2249078-44-0C7H9Cl2N3O
Methyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate dihydrochloride chemical structure, C8H13Cl2N3O2, CAS 2309447-75-2
Methyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate dihydrochloride
CAS 2309447-75-2C8H13Cl2N3O2
Methyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate chemical structure, C8H11N3O2, CAS 2309444-18-4
Methyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate
CAS 2309444-18-4C8H11N3O2
2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride chemical structure, C6H11Cl2N3, CAS 157327-48-5
2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride
CAS 157327-48-5C6H11Cl2N3
1-(Methylsulfonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole chemical structure, C6H9N3O2S, CAS 1616891-31-6
1-(Methylsulfonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole
CAS 1616891-31-6C6H9N3O2S
(S)-5-(tert-Butoxycarbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole-4-carboxylic acid chemical structure, C11H15N3O4, CAS 1827680-69-2
(S)-5-(tert-Butoxycarbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole-4-carboxylic acid
CAS 1827680-69-2C11H15N3O4
Ethyl (R)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-4-carboxylate chemical structure, C8H11N3O2, CAS 1827680-55-6
Ethyl (R)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-4-carboxylate
CAS 1827680-55-6C8H11N3O2
(R)-5-(tert-Butoxycarbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole-4-carboxylic acid chemical structure, C11H15N3O4, CAS 1827680-54-5
(R)-5-(tert-Butoxycarbonyl)-2,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole-4-carboxylic acid
CAS 1827680-54-5C11H15N3O4
2,6,6-Trimethyl-4,5-dihydropyrrolo[3,4-c]pyrazole chemical structure, C8H13N3, CAS 2749962-94-3
2,6,6-Trimethyl-4,5-dihydropyrrolo[3,4-c]pyrazole
CAS 2749962-94-3C8H13N3
2-Chloro-1-(1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)propan-1-one chemical structure, C9H12ClN3O, CAS 2411223-84-0
2-Chloro-1-(1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)propan-1-one
CAS 2411223-84-0C9H12ClN3O
2,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole-3-carbonitrile dihydrochloride chemical structure, C6H8Cl2N4, CAS 2489680-19-3
2,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole-3-carbonitrile dihydrochloride
CAS 2489680-19-3C6H8Cl2N4
5-(tert-Butyl) 4-ethyl (S)-2,6-dihydropyrrolo[3,4-C]pyrazole-4,5(4H)-dicarboxylate chemical structure, C13H19N3O4, CAS 1827680-31-8
5-(tert-Butyl) 4-ethyl (S)-2,6-dihydropyrrolo[3,4-C]pyrazole-4,5(4H)-dicarboxylate
CAS 1827680-31-8C13H19N3O4
tert-Butyl 2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate chemical structure, C10H15N3O2, CAS 2870652-71-2
tert-Butyl 2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate
CAS 2870652-71-2C10H15N3O2
2,6-Dimethyl-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazole chemical structure, C7H11N3, CAS 2749956-08-7
2,6-Dimethyl-5,6-dihydro-4H-pyrrolo[3,4-c]pyrazole
CAS 2749956-08-7C7H11N3
5-(tert-Butyl) 4-ethyl (R)-2,6-dihydropyrrolo[3,4-C]pyrazole-4,5(4H)-dicarboxylate chemical structure, C13H19N3O4, CAS 1827680-57-8
5-(tert-Butyl) 4-ethyl (R)-2,6-dihydropyrrolo[3,4-C]pyrazole-4,5(4H)-dicarboxylate
CAS 1827680-57-8C13H19N3O4
tert-Butyl 3-bromo-6,6-dimethyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(2H)-carboxylate chemical structure, C12H18BrN3O2, CAS 2567031-59-6
tert-Butyl 3-bromo-6,6-dimethyl-4,6-dihydropyrrolo[3,4-C]pyrazole-5(2H)-carboxylate
CAS 2567031-59-6C12H18BrN3O2
tert-Butyl 3-bromo-6-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate chemical structure, C11H16BrN3O2, CAS 2469600-30-2
tert-Butyl 3-bromo-6-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
CAS 2469600-30-2C11H16BrN3O2