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Murcko scaffold

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole scaffold

272 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
272
With full pages
23
Scaffold SMILES

c1n[nH]c2c1CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole page
Murcko scaffold c1n[nH]c2c1CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 272 chemicals

tert-Butyl 2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate chemical structure, C10H15N3O2, CAS 2171796-71-5
tert-Butyl 2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate
CAS 2171796-71-5C10H15N3O2
2-{1H,4H,5H,6H-Pyrrolo[3,4-c]pyrazol-1-yl}ethan-1-ol dihydrochloride chemical structure, C7H13Cl2N3O, CAS 2728156-67-8
2-{1H,4H,5H,6H-Pyrrolo[3,4-c]pyrazol-1-yl}ethan-1-ol dihydrochloride
CAS 2728156-67-8C7H13Cl2N3O
Ethyl 2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate chemical structure, C8H11N3O2, CAS 2171649-53-7
Ethyl 2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate
CAS 2171649-53-7C8H11N3O2
tert-Butyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate chemical structure, C11H17N3O2, CAS 2803834-02-6
tert-Butyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate
CAS 2803834-02-6C11H17N3O2
3-Iodo-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole hydrochloride chemical structure, C5H7ClIN3, CAS 2751620-43-4
3-Iodo-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole hydrochloride
CAS 2751620-43-4C5H7ClIN3
2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazole-3-carboxylic acid hydrochloride chemical structure, C6H8ClN3O2, CAS 2751610-77-0
2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazole-3-carboxylic acid hydrochloride
CAS 2751610-77-0C6H8ClN3O2
1-Methyl-5-(2,2,2-trifluoroacetyl)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C9H8F3N3O3, CAS 2803852-55-1
1-Methyl-5-(2,2,2-trifluoroacetyl)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2803852-55-1C9H8F3N3O3
1-Methyl-5-[(prop-2-en-1-yloxy)carbonyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C11H13N3O4, CAS 2803847-11-0
1-Methyl-5-[(prop-2-en-1-yloxy)carbonyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2803847-11-0C11H13N3O4
Ethyl1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylatehydrochloride chemical structure, C8H12ClN3O2, CAS 2731008-09-4
Ethyl1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylatehydrochloride
CAS 2731008-09-4C8H12ClN3O2
5-Acetyl-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C9H11N3O3, CAS 2803861-02-9
5-Acetyl-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2803861-02-9C9H11N3O3
2-{5-[(tert-Butoxy)carbonyl]-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetic acid chemical structure, C12H17N3O4, CAS 2172523-69-0
2-{5-[(tert-Butoxy)carbonyl]-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetic acid
CAS 2172523-69-0C12H17N3O4
3-Iodo-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole chemical structure, C6H8IN3, CAS 2803835-14-3
3-Iodo-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole
CAS 2803835-14-3C6H8IN3
Methyl 2-{2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetate chemical structure, C8H11N3O2, CAS 2172488-86-5
Methyl 2-{2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetate
CAS 2172488-86-5C8H11N3O2
Methyl1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylatehydrochloride chemical structure, C7H10ClN3O2, CAS 2803861-44-9
Methyl1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylatehydrochloride
CAS 2803861-44-9C7H10ClN3O2
tert-Butyl 4-(hydroxymethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate chemical structure, C11H17N3O3, CAS 2413899-68-8
tert-Butyl 4-(hydroxymethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate
CAS 2413899-68-8C11H17N3O3
2-Methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C7H9N3O2, CAS 2287266-52-6
2-Methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2287266-52-6C7H9N3O2
6,6-Dimethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C8H11N3O2, CAS 2287331-80-8
6,6-Dimethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2287331-80-8C8H11N3O2
tert-Butyl 3-(ethylamino)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate chemical structure, C12H20N4O2, CAS 2138027-74-2
tert-Butyl 3-(ethylamino)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate
CAS 2138027-74-2C12H20N4O2
5-[(tert-Butoxy)carbonyl]-2-(propan-2-yl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C14H21N3O4, CAS 2137503-24-1
5-[(tert-Butoxy)carbonyl]-2-(propan-2-yl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137503-24-1C14H21N3O4
5-[(tert-Butoxy)carbonyl]-2-ethyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C13H19N3O4, CAS 2137472-17-2
5-[(tert-Butoxy)carbonyl]-2-ethyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137472-17-2C13H19N3O4
5-[(tert-Butoxy)carbonyl]-2-propyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C14H21N3O4, CAS 2137448-27-0
5-[(tert-Butoxy)carbonyl]-2-propyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137448-27-0C14H21N3O4
tert-Butyl 2-(2,2,2-trifluoroethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate chemical structure, C12H16F3N3O2, CAS 2137489-54-2
tert-Butyl 2-(2,2,2-trifluoroethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylate
CAS 2137489-54-2C12H16F3N3O2
Ethyl 2-{2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetate chemical structure, C9H13N3O2, CAS 2172094-69-6
Ethyl 2-{2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetate
CAS 2172094-69-6C9H13N3O2
tert-Butyl 2-{2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetate chemical structure, C11H17N3O2, CAS 2171990-00-2
tert-Butyl 2-{2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl}acetate
CAS 2171990-00-2C11H17N3O2