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Murcko scaffold

Ring system with 4 rings and 27 atoms

45 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
45
With full pages
1
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(c2ccc(-c3ccccc3)nn2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(c2ccc(-c3ccccc3)nn2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine chemical structure, C20H19FN4O2S, CAS 478077-49-5
3-{4-[(4-Fluorophenyl)sulfonyl]piperazino}-6-phenylpyridazine
CAS 478077-49-5C20H19FN4O2S
3-{4-[(3,5-Dichlorophenyl)sulfonyl]piperazino}-6-phenylpyridazine chemical structure, C20H18Cl2N4O2S, CAS 478077-50-8
3-{4-[(3,5-Dichlorophenyl)sulfonyl]piperazino}-6-phenylpyridazine
CAS 478077-50-8C20H18Cl2N4O2S
3-(4-((2,5-Difluorophenyl)sulfonyl)piperazin-1-yl)-6-(4-methoxyphenyl)pyridazine chemical structure, C21H20F2N4O3S, CAS 1040641-55-1
3-(4-((2,5-Difluorophenyl)sulfonyl)piperazin-1-yl)-6-(4-methoxyphenyl)pyridazine
CAS 1040641-55-1C21H20F2N4O3S
3-[4-(4-Fluoro-3-methylbenzenesulfonyl)piperazin-1-yl]-6-(4-methoxyphenyl)pyridazine chemical structure, C22H23FN4O3S, CAS 1040641-62-0
3-[4-(4-Fluoro-3-methylbenzenesulfonyl)piperazin-1-yl]-6-(4-methoxyphenyl)pyridazine
CAS 1040641-62-0C22H23FN4O3S
N-[4-({4-[6-(4-Ethoxyphenyl)pyridazin-3-yl]piperazin-1-yl}sulfonyl)phenyl]acetamide chemical structure, C24H27N5O4S, CAS 1049316-31-5
N-[4-({4-[6-(4-Ethoxyphenyl)pyridazin-3-yl]piperazin-1-yl}sulfonyl)phenyl]acetamide
CAS 1049316-31-5C24H27N5O4S
3-(4-Fluorophenyl)-6-(4-((4-methoxy-3-methylphenyl)sulfonyl)piperazin-1-yl)pyridazine chemical structure, C22H23FN4O3S, CAS 1021257-10-2
3-(4-Fluorophenyl)-6-(4-((4-methoxy-3-methylphenyl)sulfonyl)piperazin-1-yl)pyridazine
CAS 1021257-10-2C22H23FN4O3S
3-(4-((5-Fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-(4-fluorophenyl)pyridazine chemical structure, C21H20F2N4O3S, CAS 1021230-80-7
3-(4-((5-Fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-(4-fluorophenyl)pyridazine
CAS 1021230-80-7C21H20F2N4O3S
3-(4-((3-Fluorophenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine chemical structure, C21H21FN4O3S, CAS 1021257-40-8
3-(4-((3-Fluorophenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine
CAS 1021257-40-8C21H21FN4O3S
3-(4-((2,4-Difluorophenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine chemical structure, C21H20F2N4O3S, CAS 1021257-45-3
3-(4-((2,4-Difluorophenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine
CAS 1021257-45-3C21H20F2N4O3S
3-[4-(3-Chlorobenzenesulfonyl)piperazin-1-yl]-6-(2-methoxyphenyl)pyridazine chemical structure, C21H21ClN4O3S, CAS 1021218-86-9
3-[4-(3-Chlorobenzenesulfonyl)piperazin-1-yl]-6-(2-methoxyphenyl)pyridazine
CAS 1021218-86-9C21H21ClN4O3S
3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine chemical structure, C21H21ClN4O3S, CAS 1021257-48-6
3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine
CAS 1021257-48-6C21H21ClN4O3S
3-(4-((4-Fluoro-3-methylphenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine chemical structure, C22H23FN4O3S, CAS 1021257-51-1
3-(4-((4-Fluoro-3-methylphenyl)sulfonyl)piperazin-1-yl)-6-(2-methoxyphenyl)pyridazine
CAS 1021257-51-1C22H23FN4O3S
3-(4-((4-Methoxy-3-methylphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C23H26N4O3S, CAS 1021257-57-7
3-(4-((4-Methoxy-3-methylphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021257-57-7C23H26N4O3S
3-(4-((2-Methoxy-5-methylphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C23H26N4O3S, CAS 1021218-95-0
3-(4-((2-Methoxy-5-methylphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021218-95-0C23H26N4O3S
3-(4-((3-Fluoro-4-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C22H23FN4O3S, CAS 1021257-60-2
3-(4-((3-Fluoro-4-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021257-60-2C22H23FN4O3S
3-(4-((5-Fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C22H23FN4O3S, CAS 1021218-97-2
3-(4-((5-Fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021218-97-2C22H23FN4O3S
3-(4-((2-Fluorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C21H21FN4O2S, CAS 1021257-63-5
3-(4-((2-Fluorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021257-63-5C21H21FN4O2S
3-(4-((2,4-Difluorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C21H20F2N4O2S, CAS 1021257-69-1
3-(4-((2,4-Difluorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021257-69-1C21H20F2N4O2S
3-(4-((3-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C21H21ClN4O2S, CAS 1021219-05-5
3-(4-((3-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021219-05-5C21H21ClN4O2S
3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C21H21ClN4O2S, CAS 1021257-72-6
3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021257-72-6C21H21ClN4O2S
3-(4-((4-Fluoro-3-methylphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine chemical structure, C22H23FN4O2S, CAS 1021257-75-9
3-(4-((4-Fluoro-3-methylphenyl)sulfonyl)piperazin-1-yl)-6-(o-tolyl)pyridazine
CAS 1021257-75-9C22H23FN4O2S
3-(4-((2-Methoxy-5-methylphenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazine chemical structure, C22H24N4O3S, CAS 1021104-11-9
3-(4-((2-Methoxy-5-methylphenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazine
CAS 1021104-11-9C22H24N4O3S
3-(4-((3,4-Dimethoxyphenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazine chemical structure, C22H24N4O4S, CAS 1021035-83-5
3-(4-((3,4-Dimethoxyphenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazine
CAS 1021035-83-5C22H24N4O4S
3-(4-((5-Fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazine chemical structure, C21H21FN4O3S, CAS 1021131-23-6
3-(4-((5-Fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)-6-phenylpyridazine
CAS 1021131-23-6C21H21FN4O3S