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Murcko scaffold

Ring system with 2 rings and 10 atoms

33 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
33
With full pages
3
Scaffold SMILES

c1noc(-c2ccsc2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1noc(-c2ccsc2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

3-(Chloromethyl)-5-(thiophen-3-yl)-1,2,4-oxadiazole chemical structure, C7H5ClN2OS, CAS 184970-24-9
3-(Chloromethyl)-5-(thiophen-3-yl)-1,2,4-oxadiazole
CAS 184970-24-9C7H5ClN2OS
5-(Thiophen-3-yl)-1,2,4-oxadiazol-3-amine chemical structure, C6H5N3OS, CAS 73631-20-6
5-(Thiophen-3-yl)-1,2,4-oxadiazol-3-amine
CAS 73631-20-6C6H5N3OS
3-Methyl-5-(thiophen-3-yl)-1,2,4-oxadiazole chemical structure, C7H6N2OS, CAS 1283108-58-6
3-Methyl-5-(thiophen-3-yl)-1,2,4-oxadiazole
CAS 1283108-58-6C7H6N2OS
3-(3-Methyl-1,2,4-oxadiazol-5-yl)thiophen-2-amine chemical structure, C7H7N3OS, CAS 1036614-40-0
3-(3-Methyl-1,2,4-oxadiazol-5-yl)thiophen-2-amine
CAS 1036614-40-0C7H7N3OS
(5-(Thiophen-3-yl)-1,2,4-oxadiazol-3-yl)methanamine chemical structure, C7H7N3OS, CAS 1221726-06-2
(5-(Thiophen-3-yl)-1,2,4-oxadiazol-3-yl)methanamine
CAS 1221726-06-2C7H7N3OS
5-(2,5-Dibromo-3-thienyl)-3-octyl-1,2,4-oxadiazole chemical structure, C14H18Br2N2OS, CAS 1260722-56-2
5-(2,5-Dibromo-3-thienyl)-3-octyl-1,2,4-oxadiazole
CAS 1260722-56-2C14H18Br2N2OS
Ethyl 5-(thiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate chemical structure, C9H8N2O3S, CAS 1339783-57-1
Ethyl 5-(thiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate
CAS 1339783-57-1C9H8N2O3S
5-(Thiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H4N2O3S, CAS 1339442-62-4
5-(Thiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1339442-62-4C7H4N2O3S
3-Chloro-5-(thiophen-3-yl)-1,2,4-oxadiazole chemical structure, C6H3ClN2OS, CAS 1443981-98-3
3-Chloro-5-(thiophen-3-yl)-1,2,4-oxadiazole
CAS 1443981-98-3C6H3ClN2OS
5-(2-Bromothiophen-3-yl)-3-methyl-1,2,4-oxadiazole chemical structure, C7H5BrN2OS, CAS 1379344-42-9
5-(2-Bromothiophen-3-yl)-3-methyl-1,2,4-oxadiazole
CAS 1379344-42-9C7H5BrN2OS
Ethyl 5-(5-iodothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate chemical structure, C9H7IN2O3S, CAS 1505115-27-4
Ethyl 5-(5-iodothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate
CAS 1505115-27-4C9H7IN2O3S
5-(5-Iodothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H3IN2O3S, CAS 1508347-42-9
5-(5-Iodothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1508347-42-9C7H3IN2O3S
Ethyl 5-(4-methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate chemical structure, C10H10N2O3S, CAS 1537413-77-6
Ethyl 5-(4-methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate
CAS 1537413-77-6C10H10N2O3S
5-(4-Methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C8H6N2O3S, CAS 1526585-35-2
5-(4-Methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1526585-35-2C8H6N2O3S
2-Ethoxy-N-[3-(3-methyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]acetamide chemical structure, C11H13N3O3S, CAS 2034243-48-4
2-Ethoxy-N-[3-(3-methyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]acetamide
CAS 2034243-48-4C11H13N3O3S
Ethyl 5-(5-bromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate chemical structure, C9H7BrN2O3S, CAS 1698631-07-0
Ethyl 5-(5-bromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylate
CAS 1698631-07-0C9H7BrN2O3S
5-(5-Bromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H3BrN2O3S, CAS 1694552-42-5
5-(5-Bromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1694552-42-5C7H3BrN2O3S
5-(2,5-Dibromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H2Br2N2O3S, CAS 1694532-60-9
5-(2,5-Dibromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1694532-60-9C7H2Br2N2O3S
5-(2,5-Dichlorothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H2Cl2N2O3S, CAS 1699654-28-8
5-(2,5-Dichlorothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1699654-28-8C7H2Cl2N2O3S
3-Methyl-5-(4-methylthiophen-3-yl)-1,2,4-oxadiazole chemical structure, C8H8N2OS, CAS 1871809-74-3
3-Methyl-5-(4-methylthiophen-3-yl)-1,2,4-oxadiazole
CAS 1871809-74-3C8H8N2OS
5-(4,5-Dimethylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C9H8N2O3S, CAS 1934495-25-6
5-(4,5-Dimethylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1934495-25-6C9H8N2O3S
5-(5-Methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C8H6N2O3S, CAS 1856593-51-5
5-(5-Methylthiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1856593-51-5C8H6N2O3S
5-(5-Chlorothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H3ClN2O3S, CAS 1880387-66-5
5-(5-Chlorothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1880387-66-5C7H3ClN2O3S
5-(2-Bromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C7H3BrN2O3S, CAS 2110996-72-8
5-(2-Bromothiophen-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 2110996-72-8C7H3BrN2O3S