Murcko scaffold
N-Cyclopentyl-5-oxo-1-phenylpyrrolidine-3-carboxamide scaffold
13 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 13
- With full pages
- 3
Scaffold SMILES
O=C(NC1CCCC1)C1CC(=O)N(c2ccccc2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 13 of 13 chemicals
N-Cyclopentyl-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 878441-89-5C16H20N2O2
N-Cyclopentyl-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 768291-60-7C17H22N2O2
N-Cyclopentyl-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide
CAS 878730-34-8C16H19FN2O2
N-Cyclopentyl-1-(4-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 879581-79-0C18H24N2O3
N-Cyclopentyl-1-(2,4-dimethoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 924980-45-0C18H24N2O4
N-Cyclopentyl-1-(2,5-dimethoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 924965-97-9C18H24N2O4
N-Cyclopentyl-1-(2-ethylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 905184-71-6C18H24N2O2
1-(3-Chloro-4-methoxyphenyl)-N-cyclopentyl-5-oxopyrrolidine-3-carboxamide
CAS 954844-71-4C17H21ClN2O3
N-[3-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-oxo-1-phenylpyrrolidine-3-carboxamide
CAS 1421445-44-4C17H22N2O4
N-(3-Hydroxy-4-(hydroxymethyl)cyclopentyl)-5-oxo-1-(p-tolyl)pyrrolidine-3-carboxamide
CAS 1421498-21-6C18H24N2O4
N-(3-Hydroxy-4-(hydroxymethyl)cyclopentyl)-1-(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 1421515-15-2C18H24N2O5
1-(4-Chlorophenyl)-N-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]-5-oxopyrrolidine-3-carboxamide
CAS 1421496-99-2C17H21ClN2O4
N-(1-Cyanocyclopentyl)-5-oxo-1-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide
CAS 1423778-02-2C18H18F3N3O2