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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 433 to 480 of 19,000 chemicals

4-Chloro-6-hydrazinyl-n-methylpyrimidin-5-amine chemical structure, C5H8ClN5, CAS 6959-81-5
4-Chloro-6-hydrazinyl-n-methylpyrimidin-5-amine
CAS 6959-81-5C5H8ClN5
4-Chloro-n-methyl-6-(1-methylhydrazinyl)pyrimidin-5-amine chemical structure, C6H10ClN5, CAS 6959-82-6
4-Chloro-n-methyl-6-(1-methylhydrazinyl)pyrimidin-5-amine
CAS 6959-82-6C6H10ClN5
Ethyl N-(4,6-dichloropyrimidin-5-yl)methanimidate chemical structure, C7H7Cl2N3O, CAS 6959-83-7
Ethyl N-(4,6-dichloropyrimidin-5-yl)methanimidate
CAS 6959-83-7C7H7Cl2N3O
4,6-Dichloro-N-methylpyrimidin-5-amine chemical structure, C5H5Cl2N3, CAS 6959-84-8
4,6-Dichloro-N-methylpyrimidin-5-amine
CAS 6959-84-8C5H5Cl2N3
N-(4,6-Dichloropyrimidin-5-yl)-2,2,2-trifluoroacetamide chemical structure, C6H2Cl2F3N3O, CAS 778-84-7
N-(4,6-Dichloropyrimidin-5-yl)-2,2,2-trifluoroacetamide
CAS 778-84-7C6H2Cl2F3N3O
4-Pyrimidinamine, 2,5-dimethoxy- chemical structure, C6H9N3O2, CAS 6960-17-4
4-Pyrimidinamine, 2,5-dimethoxy-
CAS 6960-17-4C6H9N3O2
6-Chloro-5-nitropyrimidine-2,4-diamine chemical structure, C4H4ClN5O2, CAS 6036-64-2
6-Chloro-5-nitropyrimidine-2,4-diamine
CAS 6036-64-2C4H4ClN5O2
2,4-Dichloro-5-fluoropyrimidine chemical structure, C4HCl2FN2, CAS 2927-71-1
2,4-Dichloro-5-fluoropyrimidine
CAS 2927-71-1C4HCl2FN2
N-{2-[(5-Amino-6-chloropyrimidin-4-yl)amino]ethyl}acetamide chemical structure, C8H12ClN5O, CAS 6952-99-4
N-{2-[(5-Amino-6-chloropyrimidin-4-yl)amino]ethyl}acetamide
CAS 6952-99-4C8H12ClN5O
Ethyl N-(4-amino-6-fluoropyrimidin-5-yl)methanimidate chemical structure, C7H9FN4O, CAS 708-32-7
Ethyl N-(4-amino-6-fluoropyrimidin-5-yl)methanimidate
CAS 708-32-7C7H9FN4O
2-Chloropyrimidine-4,6-dicarboxamide chemical structure, C6H5ClN4O2, CAS 7150-30-3
2-Chloropyrimidine-4,6-dicarboxamide
CAS 7150-30-3C6H5ClN4O2
2-Aminopyrimidine-4,6-dicarboxylic acid chemical structure, C6H5N3O4, CAS 500692-45-5
2-Aminopyrimidine-4,6-dicarboxylic acid
CAS 500692-45-5C6H5N3O4
2,4,6-Trichloro-5-cyanopyrimidine chemical structure, C5Cl3N3, CAS 3029-64-9
2,4,6-Trichloro-5-cyanopyrimidine
CAS 3029-64-9C5Cl3N3
Ethyl N-(6-aminopyrimidin-4-yl)carbamate chemical structure, C7H10N4O2, CAS 2852-12-2
Ethyl N-(6-aminopyrimidin-4-yl)carbamate
CAS 2852-12-2C7H10N4O2
Diethyl pyrimidine-4,6-diyldicarbamate chemical structure, C10H14N4O4, CAS 2852-13-3
Diethyl pyrimidine-4,6-diyldicarbamate
CAS 2852-13-3C10H14N4O4
6-Chloro-n4,n4-dimethylpyrimidine-2,4-diamine chemical structure, C6H9ClN4, CAS 1007-11-0
6-Chloro-n4,n4-dimethylpyrimidine-2,4-diamine
CAS 1007-11-0C6H9ClN4
5-Bromo-6-chloropyrimidine-2,4-diamine chemical structure, C4H4BrClN4, CAS 7150-68-7
5-Bromo-6-chloropyrimidine-2,4-diamine
CAS 7150-68-7C4H4BrClN4
4-Chloro-6-methyl-5-nitropyrimidin-2-amine chemical structure, C5H5ClN4O2, CAS 13162-24-8
4-Chloro-6-methyl-5-nitropyrimidin-2-amine
CAS 13162-24-8C5H5ClN4O2
4-Chloro-6-methoxy-5-nitropyrimidine chemical structure, C5H4ClN3O3, CAS 52854-14-5
4-Chloro-6-methoxy-5-nitropyrimidine
CAS 52854-14-5C5H4ClN3O3
2,4-Diamino-6-methyl-5-nitropyrimidine chemical structure, C5H7N5O2, CAS 2829-59-6
2,4-Diamino-6-methyl-5-nitropyrimidine
CAS 2829-59-6C5H7N5O2
4-Methyl-6-(methylsulfanyl)pyrimidine-2,5-diamine chemical structure, C6H10N4S, CAS 7144-21-0
4-Methyl-6-(methylsulfanyl)pyrimidine-2,5-diamine
CAS 7144-21-0C6H10N4S
N-(4,6-Dichloropyrimidin-5-yl)-N-methylnitrous amide chemical structure, C5H4Cl2N4O, CAS 7355-46-6
N-(4,6-Dichloropyrimidin-5-yl)-N-methylnitrous amide
CAS 7355-46-6C5H4Cl2N4O
6-Chloro-4-N-prop-2-enylpyrimidine-4,5-diamine chemical structure, C7H9ClN4, CAS 181304-94-9
6-Chloro-4-N-prop-2-enylpyrimidine-4,5-diamine
CAS 181304-94-9C7H9ClN4
N-[4-(2-Acetylhydrazinyl)-6-chloropyrimidin-5-yl]acetamide chemical structure, C8H10ClN5O2, CAS 90085-93-1
N-[4-(2-Acetylhydrazinyl)-6-chloropyrimidin-5-yl]acetamide
CAS 90085-93-1C8H10ClN5O2