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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 385 to 432 of 19,000 chemicals

2-Chloropyrimidine-4-carbonitrile chemical structure, C5H2ClN3, CAS 75833-38-4
2-Chloropyrimidine-4-carbonitrile
CAS 75833-38-4C5H2ClN3
2-Amino-4,6-dichloro-5-methylpyrimidine chemical structure, C5H5Cl2N3, CAS 7153-13-1
2-Amino-4,6-dichloro-5-methylpyrimidine
CAS 7153-13-1C5H5Cl2N3
Ethyl 2-(ethylthio)-4-thiocyanatopyrimidine-5-carboxylate chemical structure, C10H11N3O2S2, CAS 6628-05-3
Ethyl 2-(ethylthio)-4-thiocyanatopyrimidine-5-carboxylate
CAS 6628-05-3C10H11N3O2S2
2-Chloropyrimidine-4-carboxamide chemical structure, C5H4ClN3O, CAS 22536-66-9
2-Chloropyrimidine-4-carboxamide
CAS 22536-66-9C5H4ClN3O
2-Aminopyrimidine-4-carboxylic acid chemical structure, C5H5N3O2, CAS 2164-65-0
2-Aminopyrimidine-4-carboxylic acid
CAS 2164-65-0C5H5N3O2
4-Chloro-2,6-dihydrazinylpyrimidine chemical structure, C4H7ClN6, CAS 6972-15-2
4-Chloro-2,6-dihydrazinylpyrimidine
CAS 6972-15-2C4H7ClN6
4-Chloro-6-hydrazinylpyrimidine chemical structure, C4H5ClN4, CAS 5767-35-1
4-Chloro-6-hydrazinylpyrimidine
CAS 5767-35-1C4H5ClN4
5-Bromo-4,6-dihydrazinopyrimidine chemical structure, C4H7BrN6, CAS 825-49-0
5-Bromo-4,6-dihydrazinopyrimidine
CAS 825-49-0C4H7BrN6
6-Aminopyrimidine-4-carboxylic acid chemical structure, C5H5N3O2, CAS 38214-46-9
6-Aminopyrimidine-4-carboxylic acid
CAS 38214-46-9C5H5N3O2
N-(6-Amino-5-nitropyrimidin-4-yl)aspartic acid chemical structure, C8H9N5O6, CAS 6972-83-4
N-(6-Amino-5-nitropyrimidin-4-yl)aspartic acid
CAS 6972-83-4C8H9N5O6
2-Chloropyrimidine-4,6-dicarbonitrile chemical structure, C6HClN4, CAS 29872-58-0
2-Chloropyrimidine-4,6-dicarbonitrile
CAS 29872-58-0C6HClN4
2-Chloro-4-N-ethyl-6-(trifluoromethyl)pyrimidine-4,5-diamine chemical structure, C7H8ClF3N4, CAS 1646-07-7
2-Chloro-4-N-ethyl-6-(trifluoromethyl)pyrimidine-4,5-diamine
CAS 1646-07-7C7H8ClF3N4
2-Chloro-N-methyl-6-(trifluoromethyl)pyrimidine-4,5-diamine chemical structure, C6H6ClF3N4, CAS 1993-05-1
2-Chloro-N-methyl-6-(trifluoromethyl)pyrimidine-4,5-diamine
CAS 1993-05-1C6H6ClF3N4
6-Chloro-4-N-methyl-2-(trifluoromethyl)pyrimidine-4,5-diamine chemical structure, C6H6ClF3N4, CAS 1993-06-2
6-Chloro-4-N-methyl-2-(trifluoromethyl)pyrimidine-4,5-diamine
CAS 1993-06-2C6H6ClF3N4
6-Chloro-n4-ethyl-2-(trifluoromethyl)pyrimidine-4,5-diamine chemical structure, C7H8ClF3N4, CAS 1810-35-1
6-Chloro-n4-ethyl-2-(trifluoromethyl)pyrimidine-4,5-diamine
CAS 1810-35-1C7H8ClF3N4
6-(Methylsulfanyl)pyrimidine-4,5-diamine chemical structure, C5H8N4S, CAS 6965-92-0
6-(Methylsulfanyl)pyrimidine-4,5-diamine
CAS 6965-92-0C5H8N4S
N-(2-Acetamido-6-chloropyrimidin-4-yl)acetamide chemical structure, C8H9ClN4O2, CAS 7148-63-2
N-(2-Acetamido-6-chloropyrimidin-4-yl)acetamide
CAS 7148-63-2C8H9ClN4O2
Methyl 2,5,6-trichloropyrimidine-4-carboxylate chemical structure, C6H3Cl3N2O2, CAS 89284-85-5
Methyl 2,5,6-trichloropyrimidine-4-carboxylate
CAS 89284-85-5C6H3Cl3N2O2
4-Chloro-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine chemical structure, C6H4ClF3N2S, CAS 16097-63-5
4-Chloro-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine
CAS 16097-63-5C6H4ClF3N2S
4-Methoxy-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine chemical structure, C7H7F3N2OS, CAS 85730-33-2
4-Methoxy-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine
CAS 85730-33-2C7H7F3N2OS
2,6-Diethyl-5-methylpyrimidin-4-amine chemical structure, C9H15N3, CAS 2635-56-5
2,6-Diethyl-5-methylpyrimidin-4-amine
CAS 2635-56-5C9H15N3
Ethyl 4-amino-2-methoxypyrimidine-5-carboxylate chemical structure, C8H11N3O3, CAS 7356-61-8
Ethyl 4-amino-2-methoxypyrimidine-5-carboxylate
CAS 7356-61-8C8H11N3O3
Ethyl N-(4-amino-6-chloropyrimidin-5-yl)methanimidate chemical structure, C7H9ClN4O, CAS 91809-17-5
Ethyl N-(4-amino-6-chloropyrimidin-5-yl)methanimidate
CAS 91809-17-5C7H9ClN4O
4,6-Diaminopyrimidine-5-sulfonamide chemical structure, C4H7N5O2S, CAS 89125-21-3
4,6-Diaminopyrimidine-5-sulfonamide
CAS 89125-21-3C4H7N5O2S