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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 913 to 960 of 19,000 chemicals

4-(Bromomethyl)pyrimidine chemical structure, C5H5BrN2, CAS 54198-78-6
4-(Bromomethyl)pyrimidine
CAS 54198-78-6C5H5BrN2
4-Chloropyrimidine chemical structure, C4H3ClN2, CAS 17180-93-7
4-Chloropyrimidine
CAS 17180-93-7C4H3ClN2
5,6-Dimethylpyrimidin-4-amine chemical structure, C6H9N3, CAS 54568-12-6
5,6-Dimethylpyrimidin-4-amine
CAS 54568-12-6C6H9N3
4-(2,6-Dimethyl-pyrimidin-4-ylcarbamoyl)-butyric acid chemical structure, C11H15N3O3, CAS 797807-64-8
4-(2,6-Dimethyl-pyrimidin-4-ylcarbamoyl)-butyric acid
CAS 797807-64-8C11H15N3O3
(4-Amino-5-cyano-pyrimidin-2-ylsulfanyl)-acetic acid methyl ester chemical structure, C8H8N4O2S, CAS 483321-21-7
(4-Amino-5-cyano-pyrimidin-2-ylsulfanyl)-acetic acid methyl ester
CAS 483321-21-7C8H8N4O2S
2-(2-Ethanesulfonyl-ethylsulfanyl)-4,6-dimethyl-pyrimidine chemical structure, C10H16N2O2S2, CAS 348138-16-9
2-(2-Ethanesulfonyl-ethylsulfanyl)-4,6-dimethyl-pyrimidine
CAS 348138-16-9C10H16N2O2S2
4-Pyrimidinamine, 2-((1-methylethyl)thio)-N,N,6-trimethyl- chemical structure, C10H17N3S, CAS 154496-63-6
4-Pyrimidinamine, 2-((1-methylethyl)thio)-N,N,6-trimethyl-
CAS 154496-63-6C10H17N3S
2-[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]acetohydrazide chemical structure, C8H12N4OS, CAS 60458-71-1
2-[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]acetohydrazide
CAS 60458-71-1C8H12N4OS
2-(2-Carboxyethyl)thio-4,6-dimethylpyrimidine chemical structure, C9H12N2O2S, CAS 247225-29-2
2-(2-Carboxyethyl)thio-4,6-dimethylpyrimidine
CAS 247225-29-2C9H12N2O2S
4,6-Difluoro-N-methylpyrimidin-2-amine chemical structure, C5H5F2N3, CAS 165258-57-1
4,6-Difluoro-N-methylpyrimidin-2-amine
CAS 165258-57-1C5H5F2N3
5-Chloro-2-methylpyrimidine-4-carboxylic acid chemical structure, C6H5ClN2O2, CAS 74840-47-4
5-Chloro-2-methylpyrimidine-4-carboxylic acid
CAS 74840-47-4C6H5ClN2O2
N-Ethyl-4,6-difluoropyrimidin-2-amine chemical structure, C6H7F2N3, CAS 165258-59-3
N-Ethyl-4,6-difluoropyrimidin-2-amine
CAS 165258-59-3C6H7F2N3
4-Chloro-5-ethyl-6-methylpyrimidin-2-amine chemical structure, C7H10ClN3, CAS 162272-59-5
4-Chloro-5-ethyl-6-methylpyrimidin-2-amine
CAS 162272-59-5C7H10ClN3
4,6-Dimethoxy-N-methylpyrimidin-2-amine chemical structure, C7H11N3O2, CAS 85346-72-1
4,6-Dimethoxy-N-methylpyrimidin-2-amine
CAS 85346-72-1C7H11N3O2
2-Chloro-N-(4,6-dimethylpyrimidin-2-yl)acetamide chemical structure, C8H10ClN3O, CAS 53456-49-8
2-Chloro-N-(4,6-dimethylpyrimidin-2-yl)acetamide
CAS 53456-49-8C8H10ClN3O
N-Ethyl-4,6-dimethoxypyrimidin-2-amine chemical structure, C8H13N3O2, CAS 298219-61-1
N-Ethyl-4,6-dimethoxypyrimidin-2-amine
CAS 298219-61-1C8H13N3O2
2-Chloro-N-(pyrimidin-2-yl)acetamide chemical structure, C6H6ClN3O, CAS 52687-97-5
2-Chloro-N-(pyrimidin-2-yl)acetamide
CAS 52687-97-5C6H6ClN3O
5-Bromopyrimidine-2-carbonitrile chemical structure, C5H2BrN3, CAS 38275-57-9
5-Bromopyrimidine-2-carbonitrile
CAS 38275-57-9C5H2BrN3
(E)-5-(2-Carboxyvinyl)-2,4-dimethoxypyrimidine chemical structure, C9H10N2O4, CAS 119923-27-2
(E)-5-(2-Carboxyvinyl)-2,4-dimethoxypyrimidine
CAS 119923-27-2C9H10N2O4
4-(1,1-Dimethylethyl)-6-(trifluoromethyl)-2-pyrimidinamine chemical structure, C9H12F3N3, CAS 238742-83-1
4-(1,1-Dimethylethyl)-6-(trifluoromethyl)-2-pyrimidinamine
CAS 238742-83-1C9H12F3N3
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N,N-diethylacetamide chemical structure, C12H19N3OS, CAS 202745-93-5
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N,N-diethylacetamide
CAS 202745-93-5C12H19N3OS
Methyl 2-((2-acetamido-5-bromo-6-methylpyrimidin-4-yl)thio)acetate chemical structure, C10H12BrN3O3S, CAS 312597-83-4
Methyl 2-((2-acetamido-5-bromo-6-methylpyrimidin-4-yl)thio)acetate
CAS 312597-83-4C10H12BrN3O3S
4-((2,6-Dimethoxypyrimidin-4-yl)amino)-4-oxobutanoic acid chemical structure, C10H13N3O5, CAS 303134-31-8
4-((2,6-Dimethoxypyrimidin-4-yl)amino)-4-oxobutanoic acid
CAS 303134-31-8C10H13N3O5
Acetic acid, [[6-methyl-2-(methylthio)-4-pyrimidinyl]oxy]-, methyl ester chemical structure, C9H12N2O3S, CAS 54069-06-6
Acetic acid, [[6-methyl-2-(methylthio)-4-pyrimidinyl]oxy]-, methyl ester
CAS 54069-06-6C9H12N2O3S