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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,009 to 1,056 of 19,000 chemicals

5-Chloropyrimidine-2-carbonitrile chemical structure, C5H2ClN3, CAS 38275-56-8
5-Chloropyrimidine-2-carbonitrile
CAS 38275-56-8C5H2ClN3
4-Chloro-6-ethyl-5-methylpyrimidin-2-amine chemical structure, C7H10ClN3, CAS 162272-58-4
4-Chloro-6-ethyl-5-methylpyrimidin-2-amine
CAS 162272-58-4C7H10ClN3
4-Chloro-6-methyl-5-propyl-pyrimidin-2-ylamine chemical structure, C8H12ClN3, CAS 13208-02-1
4-Chloro-6-methyl-5-propyl-pyrimidin-2-ylamine
CAS 13208-02-1C8H12ClN3
4,6-Bis[(3-methyl-2-butenyl)sulfanyl]-5-pyrimidinecarbaldehyde chemical structure, C15H20N2OS2, CAS 251989-04-5
4,6-Bis[(3-methyl-2-butenyl)sulfanyl]-5-pyrimidinecarbaldehyde
CAS 251989-04-5C15H20N2OS2
5-Pyrimidinecarbonitrile, 4-amino-2,6-bis(methylthio)- chemical structure, C7H8N4S2, CAS 98277-53-3
5-Pyrimidinecarbonitrile, 4-amino-2,6-bis(methylthio)-
CAS 98277-53-3C7H8N4S2
4-Methyl-2-(methylsulfanyl)pyrimidine chemical structure, C6H8N2S, CAS 14001-63-9
4-Methyl-2-(methylsulfanyl)pyrimidine
CAS 14001-63-9C6H8N2S
5-Bromo-N-methylpyrimidin-4-amine chemical structure, C5H6BrN3, CAS 56181-38-5
5-Bromo-N-methylpyrimidin-4-amine
CAS 56181-38-5C5H6BrN3
2-tert-Butylpyrimidine-4,5,6-triamine chemical structure, C8H15N5, CAS 663194-12-5
2-tert-Butylpyrimidine-4,5,6-triamine
CAS 663194-12-5C8H15N5
2-tert-Butyl-4,6-dichloro-5-methylpyrimidine chemical structure, C9H12Cl2N2, CAS 663194-13-6
2-tert-Butyl-4,6-dichloro-5-methylpyrimidine
CAS 663194-13-6C9H12Cl2N2
2-tert-Butylpyrimidine-5-carboxylic acid chemical structure, C9H12N2O2, CAS 126230-73-7
2-tert-Butylpyrimidine-5-carboxylic acid
CAS 126230-73-7C9H12N2O2
2-(Dimethylamino)-4-methylpyrimidine-5-carboxylic acid chemical structure, C8H11N3O2, CAS 180283-68-5
2-(Dimethylamino)-4-methylpyrimidine-5-carboxylic acid
CAS 180283-68-5C8H11N3O2
N'-(2-Amino-6-methylpyrimidin-4-yl)acetohydrazide chemical structure, C7H11N5O, CAS 371228-24-9
N'-(2-Amino-6-methylpyrimidin-4-yl)acetohydrazide
CAS 371228-24-9C7H11N5O
4,6-Dimethoxy-2-(methylsulfonyl)pyrimidine chemical structure, C7H10N2O4S, CAS 113583-35-0
4,6-Dimethoxy-2-(methylsulfonyl)pyrimidine
CAS 113583-35-0C7H10N2O4S
2-Dimethylamino-4,6-dimethoxypyrimidine chemical structure, C8H13N3O2, CAS 56873-65-5
2-Dimethylamino-4,6-dimethoxypyrimidine
CAS 56873-65-5C8H13N3O2
Ethenamine, 2-(2,6-dimethoxy-5-nitro-4-pyrimidinyl)-N,N-dimethyl- chemical structure, C10H14N4O4, CAS 83256-18-2
Ethenamine, 2-(2,6-dimethoxy-5-nitro-4-pyrimidinyl)-N,N-dimethyl-
CAS 83256-18-2C10H14N4O4
6-Aminopyrimidine-4-carboxamide chemical structure, C5H6N4O, CAS 81333-07-5
6-Aminopyrimidine-4-carboxamide
CAS 81333-07-5C5H6N4O
2-Chloro-N-(2,6-dimethoxypyrimidin-4-yl)acetamide chemical structure, C8H10ClN3O3, CAS 330579-48-1
2-Chloro-N-(2,6-dimethoxypyrimidin-4-yl)acetamide
CAS 330579-48-1C8H10ClN3O3
2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide chemical structure, C8H11N3OS, CAS 74537-77-2
2-(4,6-Dimethylpyrimidin-2-yl)sulfanylacetamide
CAS 74537-77-2C8H11N3OS
N-(2,6-Dimethyl-pyrimidin-4-yl)-succinamic acid chemical structure, C10H13N3O3, CAS 342021-35-6
N-(2,6-Dimethyl-pyrimidin-4-yl)-succinamic acid
CAS 342021-35-6C10H13N3O3
1-Cyano-1-(4,6-dimethylpyrimidin-2-yl)-3,3-dimethylthiourea chemical structure, C10H13N5S, CAS 332373-66-7
1-Cyano-1-(4,6-dimethylpyrimidin-2-yl)-3,3-dimethylthiourea
CAS 332373-66-7C10H13N5S
2-(4,6-Dimethyl-2-pyrimidinyl)-N,2-dimethylhydrazinecarbothioamide chemical structure, C9H15N5S, CAS 115852-30-7
2-(4,6-Dimethyl-2-pyrimidinyl)-N,2-dimethylhydrazinecarbothioamide
CAS 115852-30-7C9H15N5S
Ethyl 5-chloro-2-methylsulfonylpyrimidine-4-carboxylate chemical structure, C8H9ClN2O4S, CAS 325723-07-7
Ethyl 5-chloro-2-methylsulfonylpyrimidine-4-carboxylate
CAS 325723-07-7C8H9ClN2O4S
N-(tert-Butyl)-2-((4,6-diaminopyrimidin-2-yl)thio)acetamide chemical structure, C10H17N5OS, CAS 486398-93-0
N-(tert-Butyl)-2-((4,6-diaminopyrimidin-2-yl)thio)acetamide
CAS 486398-93-0C10H17N5OS
2-((4-Methylpyrimidin-2-yl)thio)acetamide chemical structure, C7H9N3OS, CAS 74537-76-1
2-((4-Methylpyrimidin-2-yl)thio)acetamide
CAS 74537-76-1C7H9N3OS