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Murcko scaffold

Ring system with 2 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
10
With full pages
7
Scaffold SMILES

O=C(Cc1ccccc1)NCC(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NCC(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(2-Oxo-2-((4-sulfamoylphenyl)amino)ethyl)-2-phenylacetamide chemical structure, C16H17N3O4S, CAS 795282-95-0
N-(2-Oxo-2-((4-sulfamoylphenyl)amino)ethyl)-2-phenylacetamide
CAS 795282-95-0C16H17N3O4S
2-(2-Fluorophenyl)-N-[2-(2-methoxyanilino)-2-oxoethyl]-N-propylacetamide chemical structure, C20H23FN2O3, CAS 851869-95-9
2-(2-Fluorophenyl)-N-[2-(2-methoxyanilino)-2-oxoethyl]-N-propylacetamide
CAS 851869-95-9C20H23FN2O3
N-[2-(2,5-Dichloroanilino)-2-oxoethyl]-2-(2-fluorophenyl)acetamide chemical structure, C16H13Cl2FN2O2, CAS 851871-92-6
N-[2-(2,5-Dichloroanilino)-2-oxoethyl]-2-(2-fluorophenyl)acetamide
CAS 851871-92-6C16H13Cl2FN2O2
N-[2-(3-Chloroanilino)-2-oxoethyl]-2-phenylacetamide chemical structure, C16H15ClN2O2, CAS 791129-04-9
N-[2-(3-Chloroanilino)-2-oxoethyl]-2-phenylacetamide
CAS 791129-04-9C16H15ClN2O2
N-[2-(2,6-Dimethylanilino)-2-oxoethyl]-2-(2-nitrophenyl)acetamide chemical structure, C18H19N3O4, CAS 852822-76-5
N-[2-(2,6-Dimethylanilino)-2-oxoethyl]-2-(2-nitrophenyl)acetamide
CAS 852822-76-5C18H19N3O4
N-[2-(3-Cyanoanilino)-2-oxoethyl]-2-phenylacetamide chemical structure, C17H15N3O2, CAS 853593-60-9
N-[2-(3-Cyanoanilino)-2-oxoethyl]-2-phenylacetamide
CAS 853593-60-9C17H15N3O2
N-[2-(3-Acetylanilino)-2-oxoethyl]-2-phenylacetamide chemical structure, C18H18N2O3, CAS 854033-58-2
N-[2-(3-Acetylanilino)-2-oxoethyl]-2-phenylacetamide
CAS 854033-58-2C18H18N2O3
N-[2-(2-Bromoanilino)-2-oxoethyl]-2-phenylacetamide chemical structure, C16H15BrN2O2, CAS 878966-67-7
N-[2-(2-Bromoanilino)-2-oxoethyl]-2-phenylacetamide
CAS 878966-67-7C16H15BrN2O2
N-Methyl-N-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-3-(trifluoromethyl)benzeneacetamide chemical structure, C18H14F6N2O2, CAS 875446-05-2
N-Methyl-N-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-3-(trifluoromethyl)benzeneacetamide
CAS 875446-05-2C18H14F6N2O2
N-Phenylacetyl-glycin-p-anisidid chemical structure, C17H18N2O3, CAS 107523-61-5
N-Phenylacetyl-glycin-p-anisidid
CAS 107523-61-5C17H18N2O3