CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
5
With full pages
2
Scaffold SMILES

O=C(Nc1cccnc1)c1ccc(COc2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccnc1)c1ccc(COc2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

5-((4-Isopropylphenoxy)methyl)-N-(pyridin-3-yl)furan-2-carboxamide chemical structure, C20H20N2O3, CAS 693231-81-1
5-((4-Isopropylphenoxy)methyl)-N-(pyridin-3-yl)furan-2-carboxamide
CAS 693231-81-1C20H20N2O3
5-[(4-Ethoxyphenoxy)methyl]-N-(3-pyridinyl)-2-furancarboxamide chemical structure, C19H18N2O4, CAS 438472-27-6
5-[(4-Ethoxyphenoxy)methyl]-N-(3-pyridinyl)-2-furancarboxamide
CAS 438472-27-6C19H18N2O4
N-(2-Chloropyridin-3-yl)-5-[(2,4-dichlorophenoxy)methyl]furan-2-carboxamide chemical structure, C17H11Cl3N2O3, CAS 444935-21-1
N-(2-Chloropyridin-3-yl)-5-[(2,4-dichlorophenoxy)methyl]furan-2-carboxamide
CAS 444935-21-1C17H11Cl3N2O3
5-[(4-Methyl-2-nitrophenoxy)methyl]-N-pyridin-3-ylfuran-2-carboxamide chemical structure, C18H15N3O5, CAS 495386-27-1
5-[(4-Methyl-2-nitrophenoxy)methyl]-N-pyridin-3-ylfuran-2-carboxamide
CAS 495386-27-1C18H15N3O5
5-((4-(tert-Butyl)phenoxy)methyl)-N-(pyridin-3-yl)furan-2-carboxamide chemical structure, C21H22N2O3, CAS 834913-12-1
5-((4-(tert-Butyl)phenoxy)methyl)-N-(pyridin-3-yl)furan-2-carboxamide
CAS 834913-12-1C21H22N2O3